STRINGSTRING
AP1S2 AP1S2 DNM2 DNM2 ARF1 ARF1 AP4M1 AP4M1 DNASE2B DNASE2B CHMP2A CHMP2A M6PR M6PR HGS HGS SULF1 SULF1 AP4S1 AP4S1 CLHC1 CLHC1 TXNDC5 TXNDC5 AP1G1 AP1G1 H0WJR3_OTOGA H0WJR3_OTOGA AP1S1 AP1S1 ZFYVE19 ZFYVE19 RSPH9 RSPH9 AP1S3 AP1S3 DNAJC6 DNAJC6 AP1M1 AP1M1 CLVS2 CLVS2 VAMP7 VAMP7 H0XM08_OTOGA H0XM08_OTOGA CLTA CLTA AP4E1 AP4E1 H0XPM2_OTOGA H0XPM2_OTOGA BLOC1S1 BLOC1S1 AP1G2 AP1G2 H0XQI6_OTOGA H0XQI6_OTOGA TBRG4 TBRG4 SULF2 SULF2 DNASE2 DNASE2 AP1B1 AP1B1 CLTB CLTB AP4B1 AP4B1 CLVS1 CLVS1 AP5M1 AP5M1 CTSZ CTSZ AP1M2 AP1M2 SH3GL2 SH3GL2 ZFYVE1 ZFYVE1 GNS GNS VAMP8 VAMP8 ARRB1 ARRB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (817 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
DNASE2BDeoxyribonuclease 2 beta. (360 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (278 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (773 aa)
SULF1Sulfatase 1. (864 aa)
AP4S1Adaptor related protein complex 4 subunit sigma 1. (138 aa)
CLHC1Clathrin heavy chain linker domain containing 1. (597 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (419 aa)
AP1G1AP-1 complex subunit gamma. (823 aa)
H0WJR3_OTOGAV-SNARE coiled-coil homology domain-containing protein. (115 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (400 aa)
RSPH9Radial spoke head 9 homolog. (282 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (907 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
CLVS2Clavesin 2. (327 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (144 aa)
H0XM08_OTOGAUncharacterized protein. (179 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa)
AP4E1AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1137 aa)
H0XPM2_OTOGAUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
BLOC1S1Biogenesis of lysosomal organelles complex 1 subunit 1. (160 aa)
AP1G2AP-1 complex subunit gamma. (785 aa)
H0XQI6_OTOGAAP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
TBRG4Transforming growth factor beta regulator 4. (632 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (883 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (356 aa)
AP1B1AP complex subunit beta. (947 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (263 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
CLVS1Clavesin 1. (354 aa)
AP5M1Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (493 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (300 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (777 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (548 aa)
VAMP8Vesicle associated membrane protein 8. (97 aa)
ARRB1Arrestin beta 1. (418 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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