STRINGSTRING
BTRC BTRC PSMA3 PSMA3 CNBD2 CNBD2 PTRHD1 PTRHD1 ADCY3 ADCY3 PSMA7 PSMA7 ADCY2 ADCY2 IFT140 IFT140 FOPNL FOPNL ADCY8 ADCY8 PSMB2 PSMB2 ADCY9 ADCY9 IFT57 IFT57 PSMD4 PSMD4 OFD1 OFD1 WDR35 WDR35 PTCH1 PTCH1 GPR161 GPR161 NUMBL NUMBL PSMD13 PSMD13 H0WME2_OTOGA H0WME2_OTOGA PSMB7 PSMB7 PSMB4 PSMB4 PSMD8 PSMD8 ADCY1 ADCY1 TTC21A TTC21A SUFU SUFU PSMD14 PSMD14 PSMB5 PSMB5 RPGRIP1L RPGRIP1L PSMC2 PSMC2 GLI1 GLI1 INTU INTU PRKACB PRKACB GSK3B GSK3B ADCY4 ADCY4 PSMD10 PSMD10 H0WUK3_OTOGA H0WUK3_OTOGA PRKAR1B PRKAR1B IFT88 IFT88 MKS1 MKS1 PRKAR2A PRKAR2A PSMC4 PSMC4 GLIS3 GLIS3 TULP2 TULP2 KXD1 KXD1 IFT52 IFT52 PSMC5 PSMC5 PSMA6 PSMA6 PSMB3 PSMB3 H0WZC1_OTOGA H0WZC1_OTOGA TULP3 TULP3 NUMB NUMB PSME3 PSME3 TUBA1A TUBA1A PSMB6 PSMB6 PSMD5 PSMD5 PSMC6 PSMC6 IFT122 IFT122 PSME4 PSME4 PSMA4 PSMA4 PSMD3 PSMD3 PSMA8 PSMA8 ADCY7 ADCY7 PSMB1 PSMB1 PSMD12 PSMD12 PSMA1 PSMA1 THAP6 THAP6 PRKACA PRKACA PSMD1 PSMD1 WDR19 WDR19 IFT172 IFT172 GLI3 GLI3 PRKAR2B PRKAR2B TUB TUB TUBB1 TUBB1 LOC100947302 LOC100947302 PSMA5 PSMA5 SMO SMO PSMB8 PSMB8 PSMB9 PSMB9 PDCD2 PDCD2 ADCY5 ADCY5 PSMF1 PSMF1 CUL1 CUL1 PSMD7 PSMD7 PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 KIF3A KIF3A PSMB10 PSMB10 PRKAR1A PRKAR1A TTC21B TTC21B LOC100963968 LOC100963968 ITCH ITCH PSMA2 PSMA2 ADCY6 ADCY6 RBX1 RBX1 H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 H0XJC9_OTOGA H0XJC9_OTOGA SKP1 SKP1 H0XJL7_OTOGA H0XJL7_OTOGA H0XK44_OTOGA H0XK44_OTOGA DYNC2H1 DYNC2H1 GLIS1 GLIS1 H0XLK2_OTOGA H0XLK2_OTOGA H0XN06_OTOGA H0XN06_OTOGA H0XN74_OTOGA H0XN74_OTOGA TUBB6 TUBB6 THAP7 THAP7 GNAS GNAS H0XRI3_OTOGA H0XRI3_OTOGA ENSOGAP00000018960 ENSOGAP00000018960 H0XU80_OTOGA H0XU80_OTOGA H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 TUBA4A TUBA4A H0XUT0_OTOGA H0XUT0_OTOGA H0XVD2_OTOGA H0XVD2_OTOGA LOC100944801 LOC100944801 LOC100963051 LOC100963051 H0XX44_OTOGA H0XX44_OTOGA H0XX75_OTOGA H0XX75_OTOGA PSME1 PSME1 FUZ FUZ H0XYI8_OTOGA H0XYI8_OTOGA ADCY10 ADCY10 PSME2 PSME2 TULP1 TULP1 GLI2 GLI2 PSMB11 PSMB11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (526 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (582 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
IFT140Intraflagellar transport 140. (1462 aa)
FOPNLFGFR1OP N-terminal like. (174 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1120 aa)
PSMB2Proteasome subunit beta. (202 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
IFT57Intraflagellar transport 57. (429 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1006 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1180 aa)
PTCH1Patched 1. (1447 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (546 aa)
NUMBLNUMB like endocytic adaptor protein. (600 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
H0WME2_OTOGAProtein kinase domain-containing protein. (236 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
TTC21ATetratricopeptide repeat domain 21A. (1321 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
PSMB5Proteasome subunit beta. (263 aa)
RPGRIP1LRPGRIP1 like. (1103 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
GLI1GLI family zinc finger 1. (1108 aa)
INTUInturned planar cell polarity protein. (938 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
GSK3BGlycogen synthase kinase 3 beta. (387 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
IFT88Intraflagellar transport 88. (827 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (396 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
GLIS3GLIS family zinc finger 3. (931 aa)
TULP2TUB like protein 2; Belongs to the TUB family. (494 aa)
KXD1KxDL motif containing 1. (123 aa)
IFT52Intraflagellar transport 52. (436 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB3Proteasome subunit beta. (210 aa)
H0WZC1_OTOGAPDCD2_C domain-containing protein. (358 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (414 aa)
NUMBNUMB endocytic adaptor protein. (615 aa)
PSME3Proteasome activator subunit 3. (254 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
IFT122Intraflagellar transport 122. (1292 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
THAP6THAP domain containing 6. (222 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
WDR19WD repeat domain 19. (1279 aa)
IFT172Intraflagellar transport 172. (1752 aa)
GLI3GLI family zinc finger 3. (1462 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (419 aa)
TUBTubby-like protein; Belongs to the TUB family. (506 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
LOC100947302Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
PDCD2Programmed cell death 2. (344 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD7MPN domain-containing protein. (324 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (696 aa)
PSMB10Proteasome subunit beta. (273 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
TTC21BTetratricopeptide repeat domain 21B. (1313 aa)
LOC100963968Uncharacterized protein. (244 aa)
ITCHE3 ubiquitin-protein ligase. (853 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
RBX1Ring-box 1. (108 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
H0XK44_OTOGAGuanylate cyclase domain-containing protein. (1490 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4314 aa)
GLIS1GLIS family zinc finger 1. (624 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
H0XN06_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (364 aa)
H0XN74_OTOGATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
THAP7THAP domain containing 7. (304 aa)
GNASGNAS complex locus. (1146 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
ENSOGAP00000018960annotation not available (189 aa)
H0XU80_OTOGATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
LOC100963051Protein kinase domain-containing protein. (327 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
PSME1Proteasome activator subunit 1. (249 aa)
FUZFuzzy planar cell polarity protein. (447 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
ADCY10Adenylate cyclase 10. (1608 aa)
PSME2Uncharacterized protein. (239 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (545 aa)
GLI2GLI family zinc finger 2. (1522 aa)
PSMB11Proteasome subunit beta. (300 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.