STRINGSTRING
PAK1 PAK1 TAB1 TAB1 PSMA3 PSMA3 EP300 EP300 CLEC7A CLEC7A PSMA7 PSMA7 CLEC4E CLEC4E PSMB2 PSMB2 PPP3CB PPP3CB CREBBP CREBBP PSMD4 PSMD4 LYN LYN PSMD13 PSMD13 CLEC6A CLEC6A PSMB7 PSMB7 ITPR1 ITPR1 NFKBIA NFKBIA ICAM2 ICAM2 FYN FYN PRKCD PRKCD PSMB4 PSMB4 PSMD8 PSMD8 CLEC10A CLEC10A CDC34 CDC34 PSMD14 PSMD14 PAK2 PAK2 PSMB5 PSMB5 PDPK1 PDPK1 PSMC2 PSMC2 IL1B IL1B IKBKB IKBKB UBE2M UBE2M PRKACB PRKACB MAP3K7 MAP3K7 H0WTV7_OTOGA H0WTV7_OTOGA PSMD10 PSMD10 H0WUK3_OTOGA H0WUK3_OTOGA PSMC4 PSMC4 CARD11 CARD11 PLCG2 PLCG2 TRAF6 TRAF6 KXD1 KXD1 UBA3 UBA3 NFATC1 NFATC1 ERAS ERAS TAB3 TAB3 PSMC5 PSMC5 PSMA6 PSMA6 CD302 CD302 PSMB3 PSMB3 PYCARD PYCARD H0WZM7_OTOGA H0WZM7_OTOGA CLEC4D CLEC4D PSME3 PSME3 PSMB6 PSMB6 ITPR2 ITPR2 PSMD5 PSMD5 BCL10 BCL10 PSMC6 PSMC6 PSME4 PSME4 NFAT5 NFAT5 PSMA4 PSMA4 CASP8 CASP8 PSMD3 PSMD3 ICAM3 ICAM3 PSMA8 PSMA8 PSMB1 PSMB1 PPP3CA PPP3CA PSMD12 PSMD12 PSMA1 PSMA1 SYK SYK PRKACA PRKACA FBXW11 FBXW11 PSMD1 PSMD1 RELB RELB NFKB1 NFKB1 AHCYL1 AHCYL1 PSMA5 PSMA5 NFATC2 NFATC2 PSMB8 PSMB8 PSMB9 PSMB9 RPS6KA5 RPS6KA5 MAP3K20 MAP3K20 RELA RELA PSMF1 PSMF1 BTRC BTRC CUL1 CUL1 KRAS KRAS PSMD7 PSMD7 H0XCB7_OTOGA H0XCB7_OTOGA PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 SRC SRC PSMB10 PSMB10 MALT1 MALT1 PAK3 PAK3 NFKB2 NFKB2 LOC100963968 LOC100963968 WDR92 WDR92 PSMA2 PSMA2 H0XHN3_OTOGA H0XHN3_OTOGA H0XI44_OTOGA H0XI44_OTOGA H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA LOC100946771 LOC100946771 UBA52 UBA52 LOC100956330 LOC100956330 H0XJC9_OTOGA H0XJC9_OTOGA SKP1 SKP1 H0XJL7_OTOGA H0XJL7_OTOGA H0XLK2_OTOGA H0XLK2_OTOGA H0XMK6_OTOGA H0XMK6_OTOGA RAF1 RAF1 CHUK CHUK IKBKG IKBKG UBE2D1 UBE2D1 MAP3K14 MAP3K14 HRAS HRAS H0XQS4_OTOGA H0XQS4_OTOGA ITPR3 ITPR3 H0XRI3_OTOGA H0XRI3_OTOGA UBE2V1 UBE2V1 CCDC71L CCDC71L TAB2 TAB2 H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 H0XUL8_OTOGA H0XUL8_OTOGA H0XUT0_OTOGA H0XUT0_OTOGA NRAS NRAS H0XVD2_OTOGA H0XVD2_OTOGA LOC100944801 LOC100944801 H0XX44_OTOGA H0XX44_OTOGA H0XX75_OTOGA H0XX75_OTOGA CARD9 CARD9 PSME1 PSME1 H0XYI8_OTOGA H0XYI8_OTOGA PSME2 PSME2 H0XZZ5_OTOGA H0XZZ5_OTOGA NFATC3 NFATC3 PSMB11 PSMB11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAK1Non-specific serine/threonine protein kinase. (544 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (639 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
EP300E1A binding protein p300. (2420 aa)
CLEC7AC-type lectin domain containing 7A. (253 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CLEC4EC-type lectin domain family 4 member E. (211 aa)
PSMB2Proteasome subunit beta. (202 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
CREBBPCREB binding protein. (2443 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
LYNTyrosine-protein kinase. (514 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
CLEC6AC-type lectin domain containing 6A. (212 aa)
PSMB7Proteasome subunit beta. (277 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2754 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
ICAM2Intercellular adhesion molecule 2. (290 aa)
FYNTyrosine-protein kinase. (534 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
CLEC10AC-type lectin domain containing 10A. (308 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMB5Proteasome subunit beta. (263 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (559 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (729 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
H0WTV7_OTOGAUncharacterized protein. (1472 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PLCG2Phosphoinositide phospholipase C. (915 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (535 aa)
KXD1KxDL motif containing 1. (123 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
ERASES cell expressed Ras. (229 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CD302CD302 molecule. (240 aa)
PSMB3Proteasome subunit beta. (210 aa)
PYCARDPYD and CARD domain containing. (193 aa)
H0WZM7_OTOGAC-type lectin domain-containing protein. (372 aa)
CLEC4DC-type lectin domain family 4 member D. (219 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMB6Proteasome subunit beta. (239 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2647 aa)
PSMD5Uncharacterized protein. (504 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
NFAT5Nuclear factor of activated T cells 5. (1510 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (488 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
ICAM3Intercellular adhesion molecule 3. (549 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMB1Proteasome subunit beta. (235 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
SYKTyrosine-protein kinase. (629 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
FBXW11F-box and WD repeat domain containing 11. (580 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
RELBRELB proto-oncogene, NF-kB subunit. (577 aa)
NFKB1Nuclear factor kappa B subunit 1. (964 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
RPS6KA5Ribosomal protein S6 kinase. (760 aa)
MAP3K20Protein kinase domain-containing protein. (456 aa)
RELARELA proto-oncogene, NF-kB subunit. (429 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (526 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
KRASKRAS proto-oncogene, GTPase. (243 aa)
PSMD7MPN domain-containing protein. (324 aa)
H0XCB7_OTOGAEGF-like domain-containing protein. (473 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
SRCTyrosine-protein kinase. (542 aa)
PSMB10Proteasome subunit beta. (273 aa)
MALT1MALT1 paracaspase. (807 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
NFKB2Nuclear factor kappa B subunit 2. (901 aa)
LOC100963968Uncharacterized protein. (244 aa)
WDR92WD repeat domain 92. (358 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
H0XHN3_OTOGAUncharacterized protein. (499 aa)
H0XI44_OTOGAUncharacterized protein. (440 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
LOC100946771UBIQUITIN_CONJUGAT_2 domain-containing protein. (146 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC100956330UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
H0XMK6_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (708 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (747 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (420 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (948 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
H0XQS4_OTOGAMicrotubule-associated protein. (793 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2728 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
CCDC71LCoiled-coil domain containing 71 like. (234 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (698 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUL8_OTOGAC-type lectin domain-containing protein. (242 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
CARD9Caspase recruitment domain family member 9. (535 aa)
PSME1Proteasome activator subunit 1. (249 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
PSME2Uncharacterized protein. (239 aa)
H0XZZ5_OTOGAUncharacterized protein. (174 aa)
NFATC3Nuclear factor of activated T cells 3. (1036 aa)
PSMB11Proteasome subunit beta. (300 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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