STRINGSTRING
GLI3 GLI3 PSMB11 PSMB11 GLI2 GLI2 DHH DHH PSME2 PSME2 H0XYI8_OTOGA H0XYI8_OTOGA PSME1 PSME1 H0XX75_OTOGA H0XX75_OTOGA H0XX44_OTOGA H0XX44_OTOGA LOC100963051 LOC100963051 LOC100944801 LOC100944801 H0XVD2_OTOGA H0XVD2_OTOGA H0XUT0_OTOGA H0XUT0_OTOGA PSMD9 PSMD9 H0XUE4_OTOGA H0XUE4_OTOGA H0XRI3_OTOGA H0XRI3_OTOGA IQCE IQCE H0XN06_OTOGA H0XN06_OTOGA DZIP1L DZIP1L H0XLK2_OTOGA H0XLK2_OTOGA GLIS1 GLIS1 Shh Shh ARR3 ARR3 H0XJC9_OTOGA H0XJC9_OTOGA ARRB2 ARRB2 UBA52 UBA52 H0XI83_OTOGA H0XI83_OTOGA H0XI75_OTOGA H0XI75_OTOGA GAS1 GAS1 RBX1 RBX1 PSMA2 PSMA2 ITCH ITCH LOC100963968 LOC100963968 PSMB10 PSMB10 PSMD11 PSMD11 SMURF2 SMURF2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD2 PSMD2 PSMD6 PSMD6 SPOPL SPOPL PSMD7 PSMD7 PSMF1 PSMF1 IHH IHH PSMB9 PSMB9 PSMB8 PSMB8 SMO SMO PSMA5 PSMA5 SPOP SPOP PSMD1 PSMD1 CUL3 CUL3 BOC BOC PSMA1 PSMA1 ARRB1 ARRB1 PSMD12 PSMD12 PSMB1 PSMB1 PSMA8 PSMA8 PSMD3 PSMD3 GRK2 GRK2 PSMA4 PSMA4 PSME4 PSME4 PSMC6 PSMC6 SMURF1 SMURF1 PSMD5 PSMD5 PSMB6 PSMB6 PSME3 PSME3 NUMB NUMB CDON CDON PSMB3 PSMB3 PSMA6 PSMA6 PSMC5 PSMC5 GLIS3 GLIS3 HHIP HHIP PSMC4 PSMC4 H0WUK3_OTOGA H0WUK3_OTOGA PSMD10 PSMD10 ULK3 ULK3 GAS8 GAS8 EFCAB7 EFCAB7 GLI1 GLI1 PSMC2 PSMC2 PSMB5 PSMB5 PSMD14 PSMD14 SUFU SUFU DZIP1 DZIP1 PSMD8 PSMD8 PSMB4 PSMB4 PSMB7 PSMB7 H0WME2_OTOGA H0WME2_OTOGA PSMD13 PSMD13 NUMBL NUMBL GPR161 GPR161 PTCH1 PTCH1 PSMD4 PSMD4 PSMB2 PSMB2 PSMA7 PSMA7 EVC EVC EVC2 EVC2 PSMA3 PSMA3 CDC73 CDC73
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLI3GLI family zinc finger 3. (1462 aa)
PSMB11Proteasome subunit beta. (300 aa)
GLI2GLI family zinc finger 2. (1522 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (397 aa)
PSME2Uncharacterized protein. (239 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
PSME1Proteasome activator subunit 1. (249 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
LOC100963051Protein kinase domain-containing protein. (327 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
IQCEIQ motif containing E. (697 aa)
H0XN06_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (364 aa)
DZIP1LDAZ interacting zinc finger protein 1 like. (769 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
GLIS1GLIS family zinc finger 1. (624 aa)
ShhSonic hedgehog. (249 aa)
ARR3Arrestin 3. (393 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
ARRB2Arrestin beta 2. (409 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
GAS1Growth arrest specific 1. (339 aa)
RBX1Ring-box 1. (108 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ITCHE3 ubiquitin-protein ligase. (853 aa)
LOC100963968Uncharacterized protein. (244 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
SMURF2E3 ubiquitin-protein ligase. (732 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
SPOPLSpeckle type BTB/POZ protein like. (374 aa)
PSMD7MPN domain-containing protein. (324 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (276 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SPOPSpeckle type BTB/POZ protein. (374 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
BOCBOC cell adhesion associated, oncogene regulated. (974 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
ARRB1Arrestin beta 1. (418 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSME3Proteasome activator subunit 3. (254 aa)
NUMBNUMB endocytic adaptor protein. (615 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
PSMB3Proteasome subunit beta. (210 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
GLIS3GLIS family zinc finger 3. (931 aa)
HHIPHedgehog interacting protein. (700 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (473 aa)
GAS8Growth arrest specific 8. (478 aa)
EFCAB7EF-hand calcium binding domain 7. (629 aa)
GLI1GLI family zinc finger 1. (1108 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
DZIP1DAZ interacting zinc finger protein 1. (854 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMB7Proteasome subunit beta. (277 aa)
H0WME2_OTOGAProtein kinase domain-containing protein. (236 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
NUMBLNUMB like endocytic adaptor protein. (600 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (546 aa)
PTCH1Patched 1. (1447 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
PSMB2Proteasome subunit beta. (202 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
EVCEvC ciliary complex subunit 1. (993 aa)
EVC2EvC ciliary complex subunit 2. (1197 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CDC73Cell division cycle 73. (531 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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