STRINGSTRING
CSDE1 CSDE1 FGF4 FGF4 FGF5 FGF5 ERAS ERAS FGF22 FGF22 FGF23 FGF23 KL KL FGF9 FGF9 FGF20 FGF20 FGF2 FGF2 FGF6 FGF6 NRAS NRAS FGF3 FGF3 HRAS HRAS FGF8 FGF8 H0XJC1_OTOGA H0XJC1_OTOGA KRAS KRAS SHC1 SHC1 FGF10 FGF10 SOS1 SOS1 GRB2 GRB2 FGF17 FGF17 FGF1 FGF1 FGFR1 FGFR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1Cold shock domain containing E1. (813 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa)
ERASES cell expressed Ras. (229 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (167 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa)
KLKlotho. (1016 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
H0XJC1_OTOGAPID domain-containing protein. (486 aa)
KRASKRAS proto-oncogene, GTPase. (243 aa)
SHC1Uncharacterized protein. (577 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGFR1Fibroblast growth factor receptor. (792 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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