111 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMC6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	PSMD4	Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
	PSMD13	Proteasome 26S subunit, non-ATPase 13. (376 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSMD8	Proteasome 26S subunit, non-ATPase 8. (351 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (308 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
	TNFRSF8	TNF receptor superfamily member 8. (512 aa)
	TNFRSF1B	TNF receptor superfamily member 1B. (463 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
	UBE2M	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (563 aa)
	BIRC3	Baculoviral IAP repeat containing 3. (605 aa)
	PSMD10	ANK_REP_REGION domain-containing protein. (223 aa)
	H0WUK3_OTOGA	AAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	KXD1	KxDL motif containing 1. (123 aa)
	TNFSF8	TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
	UBA3	Ubiquitin like modifier activating enzyme 3. (463 aa)
	H0WXR8_OTOGA	TNFSF12-TNFSF13 readthrough; Belongs to the tumor necrosis factor family. (412 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	TNFRSF12A	TNF receptor superfamily member 12A. (129 aa)
	PSMB3	Proteasome subunit beta. (210 aa)
	PSME3	Proteasome activator subunit 3. (254 aa)
	CD40	CD40 molecule. (281 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	PSMD5	Uncharacterized protein. (504 aa)
	LTA	Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
	LTB	Lymphotoxin beta; Belongs to the tumor necrosis factor family. (245 aa)
	PSME4	Proteasome activator subunit 4. (1840 aa)
	BIRC2	Uncharacterized protein. (618 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	PSMD3	Proteasome 26S subunit, non-ATPase 3. (536 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	PSMB1	Proteasome subunit beta. (235 aa)
	TNFRSF17	TNF receptor superfamily member 17. (182 aa)
	PSMD12	Proteasome 26S subunit, non-ATPase 12. (467 aa)
	EDA2R	Ectodysplasin A2 receptor. (265 aa)
	PSMA1	Proteasome subunit alpha type. (263 aa)
	TNFSF4	TNF superfamily member 4; Belongs to the tumor necrosis factor family. (184 aa)
	FBXW11	F-box and WD repeat domain containing 11. (580 aa)
	TNFSF15	TNF superfamily member 15. (250 aa)
	TNFRSF1A	TNF receptor superfamily member 1A. (465 aa)
	CD27	CD27 molecule. (254 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (577 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	H0X902_OTOGA	TNFR-Cys domain-containing protein. (239 aa)
	TNFRSF4	TNF receptor superfamily member 4. (280 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	EDAR	Ectodysplasin A receptor. (449 aa)
	PSMF1	Proteasome inhibitor subunit 1. (271 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (526 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	PSMD7	MPN domain-containing protein. (324 aa)
	PSMD6	Proteasome 26S subunit, non-ATPase 6. (442 aa)
	PSMD2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
	H0XCY9_OTOGA	AAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
	TNFSF9	TNF superfamily member 9; Belongs to the tumor necrosis factor family. (245 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (430 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (224 aa)
	NFKB2	Nuclear factor kappa B subunit 2. (901 aa)
	LOC100963968	Uncharacterized protein. (244 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	H0XI75_OTOGA	JAB_MPN domain-containing protein. (295 aa)
	H0XI83_OTOGA	Ubiquitin-like domain-containing protein. (155 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (613 aa)
	H0XJC9_OTOGA	Uncharacterized protein. (287 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	H0XJL7_OTOGA	Uncharacterized protein. (153 aa)
	LTBR	Lymphotoxin beta receptor. (431 aa)
	LOC100951719	Uncharacterized protein. (598 aa)
	H0XLK2_OTOGA	Uncharacterized protein. (247 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (747 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (948 aa)
	TNFRSF13C	TNF receptor superfamily member 13C. (185 aa)
	TNFRSF13B	TNF receptor superfamily member 13B. (292 aa)
	H0XRI3_OTOGA	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	TNFRSF25	TNF receptor superfamily member 25. (392 aa)
	TNFRSF14	TNF receptor superfamily member 14. (283 aa)
	H0XUE4_OTOGA	Ubiquitin-like domain-containing protein. (155 aa)
	PSMD9	PDZ domain-containing protein. (223 aa)
	H0XUT0_OTOGA	AAA domain-containing protein. (392 aa)
	H0XVD2_OTOGA	ANK_REP_REGION domain-containing protein. (226 aa)
	LOC100944801	AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
	BIRC7	Baculoviral IAP repeat containing 7. (296 aa)
	H0XX44_OTOGA	Ubiquitin-like domain-containing protein. (155 aa)
	H0XX75_OTOGA	PROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
	PSME1	Proteasome activator subunit 1. (249 aa)
	H0XYI8_OTOGA	Proteasome subunit alpha type. (234 aa)
	TNFSF11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (315 aa)
	PSME2	Uncharacterized protein. (239 aa)
	H0XZQ1_OTOGA	NACHT domain-containing protein. (1439 aa)
	TNFRSF9	TNF receptor superfamily member 9. (259 aa)
	PSMB11	Proteasome subunit beta. (300 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (283 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	TNFSF14	TNF superfamily member 14; Belongs to the tumor necrosis factor family. (241 aa)
	CD70	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (190 aa)
	TNFRSF11B	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
	PSMB2	Proteasome subunit beta. (202 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC2	BIRC7	ENSOGAP00000009285	ENSOGAP00000020355	Uncharacterized protein.	Baculoviral IAP repeat containing 7.	0.892
BIRC2	CD40	ENSOGAP00000009285	ENSOGAP00000008618	Uncharacterized protein.	CD40 molecule.	0.586
BIRC2	CD40LG	ENSOGAP00000009285	ENSOGAP00000004983	Uncharacterized protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.635
BIRC2	CHUK	ENSOGAP00000009285	ENSOGAP00000017551	Uncharacterized protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.662
BIRC2	CUL1	ENSOGAP00000009285	ENSOGAP00000013190	Uncharacterized protein.	Cullin 1; Belongs to the cullin family.	0.641
BIRC2	EDA	ENSOGAP00000009285	ENSOGAP00000014569	Uncharacterized protein.	Ectodysplasin A; Belongs to the tumor necrosis factor family.	0.499
BIRC2	H0WUK3_OTOGA	ENSOGAP00000009285	ENSOGAP00000005920	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.411
BIRC2	H0X902_OTOGA	ENSOGAP00000009285	ENSOGAP00000011999	Uncharacterized protein.	TNFR-Cys domain-containing protein.	0.473
BIRC2	H0XI75_OTOGA	ENSOGAP00000009285	ENSOGAP00000015815	Uncharacterized protein.	JAB_MPN domain-containing protein.	0.488
BIRC2	H0XI83_OTOGA	ENSOGAP00000009285	ENSOGAP00000015823	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.817
BIRC2	H0XJC9_OTOGA	ENSOGAP00000009285	ENSOGAP00000016219	Uncharacterized protein.	Uncharacterized protein.	0.419
BIRC2	H0XJL7_OTOGA	ENSOGAP00000009285	ENSOGAP00000016307	Uncharacterized protein.	Uncharacterized protein.	0.860
BIRC2	H0XRI3_OTOGA	ENSOGAP00000009285	ENSOGAP00000018725	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.411
BIRC2	H0XUE4_OTOGA	ENSOGAP00000009285	ENSOGAP00000019736	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.817
BIRC2	H0XVD2_OTOGA	ENSOGAP00000009285	ENSOGAP00000020074	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.456
BIRC2	H0XX44_OTOGA	ENSOGAP00000009285	ENSOGAP00000020687	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.817
BIRC2	H0XZQ1_OTOGA	ENSOGAP00000009285	ENSOGAP00000021594	Uncharacterized protein.	NACHT domain-containing protein.	0.776
BIRC2	LOC100944801	ENSOGAP00000009285	ENSOGAP00000020287	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.411
BIRC2	LOC100963968	ENSOGAP00000009285	ENSOGAP00000014845	Uncharacterized protein.	Uncharacterized protein.	0.416
BIRC2	LTA	ENSOGAP00000009285	ENSOGAP00000009162	Uncharacterized protein.	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	0.511