STRINGSTRING
JUN JUN H0XLK2_OTOGA H0XLK2_OTOGA DNAJB13 DNAJB13 H0XJL7_OTOGA H0XJL7_OTOGA H0XJC9_OTOGA H0XJC9_OTOGA BRSK2 BRSK2 H0XI83_OTOGA H0XI83_OTOGA H0XI75_OTOGA H0XI75_OTOGA PSMA2 PSMA2 MAPK4 MAPK4 LOC100963968 LOC100963968 ETV1 ETV1 PAK3 PAK3 PSMB10 PSMB10 PAK2 PAK2 PSMD14 PSMD14 TMEM232 TMEM232 EIF2C4 EIF2C4 IGF2BP1 IGF2BP1 PSMA7 PSMA7 PSMA3 PSMA3 XPO1 XPO1 PSMD8 PSMD8 PSMB4 PSMB4 BRSK1 BRSK1 PSMB7 PSMB7 PSMD13 PSMD13 PSMD4 PSMD4 PSMB2 PSMB2 PSMD1 PSMD1 MAPKAPK5 MAPKAPK5 RSPH4A RSPH4A PRKACA PRKACA PSMA1 PSMA1 PSMD12 PSMD12 PSMB1 PSMB1 PSMA8 PSMA8 TNRC6B TNRC6B PSMD3 PSMD3 DUSP23 DUSP23 PSMA4 PSMA4 PSME4 PSME4 AGO3 AGO3 AGO1 AGO1 PSMC6 PSMC6 CDK1 CDK1 PSMD5 PSMD5 CDKN3 CDKN3 CDC14A CDC14A PSMB6 PSMB6 PSME3 PSME3 PSMB3 PSMB3 DNAJB5 DNAJB5 PSMA6 PSMA6 PSMC5 PSMC5 PAK1 PAK1 AGO2 AGO2 CDC14B CDC14B ETV4 ETV4 HSPB1 HSPB1 KXD1 KXD1 NCOA3 NCOA3 PSMC4 PSMC4 H0WUK3_OTOGA H0WUK3_OTOGA PSMD10 PSMD10 PRKACB PRKACB MYC MYC PSMC2 PSMC2 PSMB5 PSMB5 RSPH6A RSPH6A PSMA5 PSMA5 PSMB8 PSMB8 PSMB9 PSMB9 DNAJB1 DNAJB1 MOV10 MOV10 DNAJB4 DNAJB4 CDC42 CDC42 PSMF1 PSMF1 PSMD7 PSMD7 KALRN KALRN PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 PSMB11 PSMB11 H0Y1Y3_OTOGA H0Y1Y3_OTOGA H0Y105_OTOGA H0Y105_OTOGA EIF2C4-2 EIF2C4-2 PSME2 PSME2 CDC42EP3 CDC42EP3 SEPTIN7 SEPTIN7 H0XYI8_OTOGA H0XYI8_OTOGA PSME1 PSME1 H0XX75_OTOGA H0XX75_OTOGA H0XX44_OTOGA H0XX44_OTOGA CCND3 CCND3 LOC100944801 LOC100944801 Q71BM6_OTOGA Q71BM6_OTOGA MAPK6 MAPK6 H0XVD2_OTOGA H0XVD2_OTOGA LOC100943441 LOC100943441 H0XUT0_OTOGA H0XUT0_OTOGA PSMD9 PSMD9 H0XUE4_OTOGA H0XUE4_OTOGA FOXO1 FOXO1 LOC100947706 LOC100947706 H0XRI3_OTOGA H0XRI3_OTOGA FOXO3 FOXO3 CDC42EP2 CDC42EP2 CDC42EP5 CDC42EP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (329 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
BRSK2BR serine/threonine kinase 2. (706 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
MAPK4Mitogen-activated protein kinase 4. (588 aa)
LOC100963968Uncharacterized protein. (244 aa)
ETV1ETS variant 1. (469 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PSMB10Proteasome subunit beta. (273 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
TMEM232Transmembrane protein 232. (524 aa)
EIF2C4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (789 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
XPO1Exportin 1. (1048 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
BRSK1BR serine/threonine kinase 1. (781 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
PSMB2Proteasome subunit beta. (202 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
MAPKAPK5MAPK activated protein kinase 5. (463 aa)
RSPH4ARadial spoke head component 4A. (718 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1837 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
DUSP23Dual specificity phosphatase 23. (155 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (859 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
PSMD5Uncharacterized protein. (504 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (209 aa)
CDC14ACell division cycle 14A. (622 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMB3Proteasome subunit beta. (210 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (348 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (853 aa)
CDC14BUncharacterized protein. (444 aa)
ETV4ETS variant 4. (487 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (198 aa)
KXD1KxDL motif containing 1. (123 aa)
NCOA3Nuclear receptor coactivator. (1423 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
PSMB5Proteasome subunit beta. (263 aa)
RSPH6ARadial spoke head 6 homolog A. (712 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
CDC42Uncharacterized protein. (191 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD7MPN domain-containing protein. (324 aa)
KALRNKalirin RhoGEF kinase. (2985 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
PSMB11Proteasome subunit beta. (300 aa)
H0Y1Y3_OTOGAProtein kinase domain-containing protein. (468 aa)
H0Y105_OTOGAV(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (271 aa)
EIF2C4-2Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
PSME2Uncharacterized protein. (239 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (427 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
PSME1Proteasome activator subunit 1. (249 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
Q71BM6_OTOGARAG2. (148 aa)
MAPK6Mitogen-activated protein kinase 6. (722 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100943441Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
FOXO1Forkhead box O1. (655 aa)
LOC100947706Uncharacterized protein. (191 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
FOXO3Forkhead box O3. (672 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
CDC42EP5CDC42 effector protein 5. (153 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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