STRINGSTRING
LOC100945989 LOC100945989 MCM4 MCM4 PSMA3 PSMA3 ORC6 ORC6 ANAPC5 ANAPC5 PSMA7 PSMA7 H0WHP7_OTOGA H0WHP7_OTOGA CDK3 CDK3 ANAPC4 ANAPC4 PSMB2 PSMB2 PSMD4 PSMD4 KPNA1 KPNA1 PSMD13 PSMD13 CDC23 CDC23 H2AZ1 H2AZ1 PSMB7 PSMB7 UBE2S UBE2S ORC4 ORC4 PSMB4 PSMB4 PSMD8 PSMD8 PSMD14 PSMD14 FAM89A FAM89A LOC100960730 LOC100960730 H0WR29_OTOGA H0WR29_OTOGA MCM9 MCM9 PSMB5 PSMB5 PSMC2 PSMC2 H0WSK8_OTOGA H0WSK8_OTOGA DBF4 DBF4 ANAPC2 ANAPC2 LOC100945040 LOC100945040 KPNB1 KPNB1 LOC100959075 LOC100959075 H2BC21 H2BC21 H2AC20 H2AC20 PSMD10 PSMD10 H0WUK3_OTOGA H0WUK3_OTOGA POLE POLE PSMC4 PSMC4 ANAPC10 ANAPC10 CDK2 CDK2 KXD1 KXD1 UBE2E1 UBE2E1 H0WXD6_OTOGA H0WXD6_OTOGA LOC105888222 LOC105888222 LOC100942503 LOC100942503 LOC100941637 LOC100941637 H2BC5 H2BC5 LOC100940363 LOC100940363 H0WXI2_OTOGA H0WXI2_OTOGA LOC100942189 LOC100942189 LOC105888222-2 LOC105888222-2 LOC100958063 LOC100958063 H4C8 H4C8 ANAPC16 ANAPC16 PSMC5 PSMC5 PSMA6 PSMA6 ORC5 ORC5 CDC6 CDC6 MCM6 MCM6 PSMB3 PSMB3 PSME3 PSME3 KPNA6 KPNA6 LOC100948041 LOC100948041 PSMB6 PSMB6 PSMD5 PSMD5 PSMC6 PSMC6 MCM2 MCM2 PSMA4 PSMA4 CDC16 CDC16 PSMD3 PSMD3 PSMB1 PSMB1 PSMD12 PSMD12 PSMA1 PSMA1 PSMD1 PSMD1 ORC2 ORC2 MCM8 MCM8 POLE2 POLE2 ANAPC7 ANAPC7 PSMA5 PSMA5 PSMB8 PSMB8 PSMB9 PSMB9 FZR1 FZR1 POLA1 POLA1 PSMF1 PSMF1 POLA2 POLA2 PSMD7 PSMD7 PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA ORC1 ORC1 PSMD11 PSMD11 MCM5 MCM5 MCM3 MCM3 PSMB10 PSMB10 RPA2 RPA2 POLE4 POLE4 CDC27 CDC27 ORC3 ORC3 LOC100940682 LOC100940682 LOC100942503-4 LOC100942503-4 LOC100942503-5 LOC100942503-5 LOC105888222-3 LOC105888222-3 LOC100963968 LOC100963968 PSMA2 PSMA2 MCM7 MCM7 LOC100962662 LOC100962662 LOC100942503-6 LOC100942503-6 H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 H0XIX9_OTOGA H0XIX9_OTOGA LOC100957578 LOC100957578 RPA3 RPA3 H0XJC9_OTOGA H0XJC9_OTOGA H0XJL7_OTOGA H0XJL7_OTOGA CDT1 CDT1 LOC105888222-4 LOC105888222-4 H0XLJ0_OTOGA H0XLJ0_OTOGA H0XLK2_OTOGA H0XLK2_OTOGA CDC7 CDC7 RPA1 RPA1 LOC100958180 LOC100958180 LOC100945692 LOC100945692 POLE3 POLE3 H0XNJ8_OTOGA H0XNJ8_OTOGA LOC100942503-8 LOC100942503-8 H2BC1 H2BC1 LOC100961925 LOC100961925 H0XPJ8_OTOGA H0XPJ8_OTOGA H2BC11 H2BC11 H0XPX5_OTOGA H0XPX5_OTOGA CDC26 CDC26 UBE2D1 UBE2D1 LOC100941637-2 LOC100941637-2 LOC100957578-2 LOC100957578-2 H2AX H2AX LOC100942503-9 LOC100942503-9 H0XR91_OTOGA H0XR91_OTOGA H0XRI3_OTOGA H0XRI3_OTOGA H0XRL0_OTOGA H0XRL0_OTOGA ANAPC15 ANAPC15 H0XSP9_OTOGA H0XSP9_OTOGA H2AZ2 H2AZ2 LOC100944154 LOC100944154 H0XTG3_OTOGA H0XTG3_OTOGA H0XTS9_OTOGA H0XTS9_OTOGA LOC100944085 LOC100944085 H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 H0XUP0_OTOGA H0XUP0_OTOGA H0XUT0_OTOGA H0XUT0_OTOGA LOC100942189-2 LOC100942189-2 H0XV82_OTOGA H0XV82_OTOGA H0XVD2_OTOGA H0XVD2_OTOGA H0XVG4_OTOGA H0XVG4_OTOGA LOC100962662-2 LOC100962662-2 LOC100944801 LOC100944801 LOC100966022 LOC100966022 LOC105888222-5 LOC105888222-5 FAM89B FAM89B H0XX44_OTOGA H0XX44_OTOGA H0XX75_OTOGA H0XX75_OTOGA ANAPC1 ANAPC1 PSME1 PSME1 ANAPC11 ANAPC11 H0XY95_OTOGA H0XY95_OTOGA CDC45 CDC45 H0XYI8_OTOGA H0XYI8_OTOGA H0XYJ3_OTOGA H0XYJ3_OTOGA H2AC6 H2AC6 H0XZ35_OTOGA H0XZ35_OTOGA H2BC14 H2BC14 PSME2 PSME2 LOC100946065 LOC100946065 LOC100956001 LOC100956001 LOC105888222-6 LOC105888222-6 LOC100942503-11 LOC100942503-11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100945989Histone H2B; Belongs to the histone H2B family. (135 aa)
MCM4DNA helicase; Belongs to the MCM family. (867 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
H0WHP7_OTOGAUncharacterized protein. (122 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
PSMB2Proteasome subunit beta. (202 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (462 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
CDC23Cell division cycle 23. (597 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMB7Proteasome subunit beta. (277 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (217 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
FAM89AFamily with sequence similarity 89 member A. (182 aa)
LOC100960730Uncharacterized protein. (210 aa)
H0WR29_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (658 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
H0WSK8_OTOGAUncharacterized protein. (173 aa)
DBF4DBF4 zinc finger. (678 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (834 aa)
LOC100945040Histone H3; Belongs to the histone H3 family. (136 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
LOC100959075Histone H3; Belongs to the histone H3 family. (136 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
KXD1KxDL motif containing 1. (123 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
H0WXD6_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
LOC105888222Histone H3.1. (136 aa)
LOC100942503Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100941637Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100940363Histone H2A; Belongs to the histone H2A family. (130 aa)
H0WXI2_OTOGAHistone H2B; Belongs to the histone H2B family. (135 aa)
LOC100942189Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105888222-2Histone H3.1. (136 aa)
LOC100958063Histone H3.1. (136 aa)
H4C8Histone H4. (103 aa)
ANAPC16Uncharacterized protein. (110 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa)
MCM6DNA helicase; Belongs to the MCM family. (822 aa)
PSMB3Proteasome subunit beta. (210 aa)
PSME3Proteasome activator subunit 3. (254 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (535 aa)
LOC100948041Mcm10 domain-containing protein. (873 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CDC16Cell division cycle 16. (553 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
ORC2Origin recognition complex subunit 2. (580 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (832 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
POLA1DNA polymerase. (1353 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
PSMD7MPN domain-containing protein. (324 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
ORC1Origin recognition complex subunit 1. (727 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
MCM3DNA helicase; Belongs to the MCM family. (791 aa)
PSMB10Proteasome subunit beta. (273 aa)
RPA2Replication protein A2. (268 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
CDC27Cell division cycle 27. (826 aa)
ORC3Origin recognition complex subunit 3. (672 aa)
LOC100940682Histone H2B type 1. (126 aa)
LOC100942503-4Histone H4. (103 aa)
LOC100942503-5Histone H4. (103 aa)
LOC105888222-3Histone H3.1. (136 aa)
LOC100963968Uncharacterized protein. (244 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
LOC100962662Histone H3. (136 aa)
LOC100942503-6Histone H4. (103 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XIX9_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100957578Histone H2B type 2-E. (126 aa)
RPA3Uncharacterized protein. (121 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
CDT1Chromatin licensing and DNA replication factor 1. (552 aa)
LOC105888222-4Histone H3.1. (136 aa)
H0XLJ0_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (122 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
CDC7Cell division cycle 7. (576 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (642 aa)
LOC100958180Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100945692Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
H0XNJ8_OTOGAUncharacterized protein. (473 aa)
LOC100942503-8Histone H4. (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (136 aa)
LOC100961925Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XPJ8_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XPX5_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (141 aa)
CDC26Cell division cycle 26. (85 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC100941637-2Histone H2B type 1. (126 aa)
LOC100957578-2Histone H2B type 2-E. (126 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC100942503-9Histone H4. (103 aa)
H0XR91_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (169 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
H0XRL0_OTOGAUncharacterized protein. (211 aa)
ANAPC15Anaphase promoting complex subunit 15. (159 aa)
H0XSP9_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (121 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (127 aa)
LOC100944154Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XTG3_OTOGAHistone domain-containing protein. (135 aa)
H0XTS9_OTOGAUncharacterized protein. (147 aa)
LOC100944085Histone H2B; Belongs to the histone H2B family. (137 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUP0_OTOGAUncharacterized protein. (178 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
LOC100942189-2Histone H2A type 1-B/E. (130 aa)
H0XV82_OTOGAHistone domain-containing protein. (84 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
H0XVG4_OTOGAUncharacterized protein. (174 aa)
LOC100962662-2Histone H3. (136 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
LOC100966022Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC105888222-5Histone H3.1. (136 aa)
FAM89BFamily with sequence similarity 89 member B. (186 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
H0XY95_OTOGAUncharacterized protein. (110 aa)
CDC45Cell division cycle 45. (616 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
H0XYJ3_OTOGAUncharacterized protein. (180 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H0XZ35_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (165 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
PSME2Uncharacterized protein. (239 aa)
LOC100946065Histone H3.3. (136 aa)
LOC100956001UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
LOC105888222-6Histone H3.1. (136 aa)
LOC100942503-11Histone H4. (103 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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