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| | E2F4 | E2F transcription factor 4. (403 aa) |
| | TFDP2 | Transcription factor. (426 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (867 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (193 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PDS5B | PDS5 cohesin associated factor B. (1448 aa) |
| | LIG1 | DNA ligase. (890 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | H0WHP7_OTOGA | Uncharacterized protein. (122 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1856 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | PSMB2 | Proteasome subunit beta. (202 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (751 aa) |
| | PSMD4 | Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa) |
| | CDC25A | Cell division cycle 25A. (525 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1236 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (217 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (351 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (245 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (308 aa) |
| | FAM89A | Family with sequence similarity 89 member A. (182 aa) |
| | LOC100960730 | Uncharacterized protein. (210 aa) |
| | H0WR29_OTOGA | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (658 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa) |
| | POLD1 | DNA polymerase. (1109 aa) |
| | H0WSK8_OTOGA | Uncharacterized protein. (173 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (834 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta. (387 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa) |
| | PSMD10 | ANK_REP_REGION domain-containing protein. (223 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | H0WUK3_OTOGA | AAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) |
| | STAG1 | Stromal antigen 1. (1161 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | SKP2 | F-box domain-containing protein. (424 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (548 aa) |
| | H0WW89_OTOGA | Uncharacterized protein. (615 aa) |
| | RB1 | RB transcriptional corepressor 1. (929 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (551 aa) |
| | KXD1 | KxDL motif containing 1. (123 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | ESCO1 | Uncharacterized protein. (845 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (562 aa) |
| | H0WXW8_OTOGA | WAPL domain-containing protein. (1192 aa) |
| | RFC5 | Replication factor C subunit 5. (343 aa) |
| | ANAPC16 | Uncharacterized protein. (110 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | CDC25B | Cell division cycle 25B. (514 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | H0WYM5_OTOGA | Uncharacterized protein. (549 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (822 aa) |
| | PSMB3 | Proteasome subunit beta. (210 aa) |
| | PSME3 | Proteasome activator subunit 3. (254 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | PSMD5 | Uncharacterized protein. (504 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | PSME4 | Proteasome activator subunit 4. (1840 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (426 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (323 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | RFC4 | Replication factor C subunit 4. (365 aa) |
| | CDC16 | Cell division cycle 16. (553 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (536 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (930 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | PSMB1 | Proteasome subunit beta. (235 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (467 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | WEE1 | Wee1-like protein kinase. (643 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | ESCO2 | Establishment of sister chromatid cohesion N-acetyltransferase 2. (605 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | RFC1 | Replication factor C subunit 1. (1075 aa) |
| | ORC2 | Origin recognition complex subunit 2. (580 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (832 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | E2F5 | E2F transcription factor 5. (347 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (565 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | POLA1 | DNA polymerase. (1353 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (554 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | PSMD7 | MPN domain-containing protein. (324 aa) |
| | RFC2 | Replication factor C subunit 2. (354 aa) |
| | H0XCB4_OTOGA | Uncharacterized protein. (433 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | H0XCY9_OTOGA | AAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa) |
| | ORC1 | Origin recognition complex subunit 1. (727 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (430 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (791 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | POLD3 | DNA polymerase delta 3, accessory subunit. (466 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | CDC27 | Cell division cycle 27. (826 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (285 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ORC3 | Origin recognition complex subunit 3. (672 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | LOC100963968 | Uncharacterized protein. (244 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | H0XGN3_OTOGA | Uncharacterized protein. (622 aa) |
| | H0XI75_OTOGA | JAB_MPN domain-containing protein. (295 aa) |
| | H0XI83_OTOGA | Ubiquitin-like domain-containing protein. (155 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | RPA3 | Uncharacterized protein. (121 aa) |
| | H0XJC9_OTOGA | Uncharacterized protein. (287 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | H0XJL7_OTOGA | Uncharacterized protein. (153 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (552 aa) |
| | H0XL98_OTOGA | Uncharacterized protein. (475 aa) |
| | H0XLG8_OTOGA | WAPL domain-containing protein. (1135 aa) |
| | H0XLK2_OTOGA | Uncharacterized protein. (247 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (642 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | H0XNJ8_OTOGA | Uncharacterized protein. (473 aa) |
| | MAX | MYC associated factor X. (166 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | H0XPJ8_OTOGA | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | H0XPR2_OTOGA | DIRP domain-containing protein. (496 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | H0XRI3_OTOGA | AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa) |
| | H0XRL0_OTOGA | Uncharacterized protein. (211 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (159 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | H0XS38_OTOGA | F-box domain-containing protein. (410 aa) |
| | E2F1 | E2F transcription factor 1. (385 aa) |
| | H0XSX2_OTOGA | Uncharacterized protein. (584 aa) |
| | H0XT29_OTOGA | zf-C2H2_3 domain-containing protein. (723 aa) |
| | H0XTC3_OTOGA | DIRP domain-containing protein. (496 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (321 aa) |
| | H0XU64_OTOGA | BHLH domain-containing protein. (146 aa) |
| | H0XUE4_OTOGA | Ubiquitin-like domain-containing protein. (155 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | H0XUT0_OTOGA | AAA domain-containing protein. (392 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | H0XVD2_OTOGA | ANK_REP_REGION domain-containing protein. (226 aa) |
| | LOC100944801 | AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | H0XWX5_OTOGA | Wee1-like protein kinase. (561 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (186 aa) |
| | H0XX44_OTOGA | Ubiquitin-like domain-containing protein. (155 aa) |
| | H0XX75_OTOGA | PROTEASOME_ALPHA_1 domain-containing protein. (231 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | H0XY95_OTOGA | Uncharacterized protein. (110 aa) |
| | CDC45 | Cell division cycle 45. (616 aa) |
| | H0XYI8_OTOGA | Proteasome subunit alpha type. (234 aa) |
| | H0XYJ3_OTOGA | Uncharacterized protein. (180 aa) |
| | H0XZ85_OTOGA | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa) |
| | PSME2 | Uncharacterized protein. (239 aa) |
| | LOC100956001 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | H0Y2L0_OTOGA | Sld5 domain-containing protein. (72 aa) |
