STRINGSTRING
H0XWX5_OTOGA H0XWX5_OTOGA E2F4 E2F4 TFDP2 TFDP2 PSMA3 PSMA3 CDKN1A CDKN1A PSMA7 PSMA7 CDK3 CDK3 PSMB2 PSMB2 LIN54 LIN54 PSMD4 PSMD4 CDC25A CDC25A LIN52 LIN52 PSMD13 PSMD13 PSMB7 PSMB7 TFDP1 TFDP1 CDKN1B CDKN1B PSMB4 PSMB4 PSMD8 PSMD8 LIN37 LIN37 PSMD14 PSMD14 PSMB5 PSMB5 PSMC2 PSMC2 MYC MYC CCNE1 CCNE1 CKS1B CKS1B PSMD10 PSMD10 H0WUK3_OTOGA H0WUK3_OTOGA PSMC4 PSMC4 CDK2 CDK2 SKP2 SKP2 LIN9 LIN9 H0WW89_OTOGA H0WW89_OTOGA RB1 RB1 KXD1 KXD1 CABLES1 CABLES1 PSMC5 PSMC5 CDC25B CDC25B PSMA6 PSMA6 H0WYM5_OTOGA H0WYM5_OTOGA PSMB3 PSMB3 PSME3 PSME3 PSMB6 PSMB6 PSMD5 PSMD5 PSMC6 PSMC6 CCNA1 CCNA1 CCNH CCNH PSMA4 PSMA4 CDK7 CDK7 PSMD3 PSMD3 PSMB1 PSMB1 PSMD12 PSMD12 CCND1 CCND1 WEE1 WEE1 PSMA1 PSMA1 PSMD1 PSMD1 E2F5 E2F5 PSMA5 PSMA5 PSMB8 PSMB8 PSMB9 PSMB9 AKT2 AKT2 FZR1 FZR1 CDK4 CDK4 RBL2 RBL2 PSMF1 PSMF1 CUL1 CUL1 PSMD7 PSMD7 PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 PSMB10 PSMB10 MNAT1 MNAT1 CCNA2 CCNA2 AKT3 AKT3 LOC100963968 LOC100963968 PSMA2 PSMA2 H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 H0XJC9_OTOGA H0XJC9_OTOGA SKP1 SKP1 H0XJL7_OTOGA H0XJL7_OTOGA H0XLK2_OTOGA H0XLK2_OTOGA MAX MAX WEE2 WEE2 AKT1 AKT1 H0XPR2_OTOGA H0XPR2_OTOGA H0XRI3_OTOGA H0XRI3_OTOGA H0XS38_OTOGA H0XS38_OTOGA E2F1 E2F1 H0XTC3_OTOGA H0XTC3_OTOGA CCNE2 CCNE2 H0XU64_OTOGA H0XU64_OTOGA H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 H0XUT0_OTOGA H0XUT0_OTOGA CKS2 CKS2 H0XVD2_OTOGA H0XVD2_OTOGA LOC100944801 LOC100944801 H0XX44_OTOGA H0XX44_OTOGA H0XX75_OTOGA H0XX75_OTOGA PSME1 PSME1 H0XYI8_OTOGA H0XYI8_OTOGA H0XZ85_OTOGA H0XZ85_OTOGA PSME2 PSME2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H0XWX5_OTOGAWee1-like protein kinase. (561 aa)
E2F4E2F transcription factor 4. (403 aa)
TFDP2Transcription factor. (426 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (193 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
PSMB2Proteasome subunit beta. (202 aa)
LIN54Lin-54 DREAM MuvB core complex component. (751 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
CDC25ACell division cycle 25A. (525 aa)
LIN52Lin-52 DREAM MuvB core complex component. (116 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSMB7Proteasome subunit beta. (277 aa)
TFDP1Transcription factor. (410 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
LIN37Lin-37 DREAM MuvB core complex component. (245 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
SKP2F-box domain-containing protein. (424 aa)
LIN9Lin-9 DREAM MuvB core complex component. (548 aa)
H0WW89_OTOGAUncharacterized protein. (615 aa)
RB1RB transcriptional corepressor 1. (929 aa)
KXD1KxDL motif containing 1. (123 aa)
CABLES1Cdk5 and Abl enzyme substrate 1. (562 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CDC25BCell division cycle 25B. (514 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
H0WYM5_OTOGAUncharacterized protein. (549 aa)
PSMB3Proteasome subunit beta. (210 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (426 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
WEE1Wee1-like protein kinase. (643 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
E2F5E2F transcription factor 5. (347 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD7MPN domain-containing protein. (324 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
PSMB10Proteasome subunit beta. (273 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (285 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC100963968Uncharacterized protein. (244 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
MAXMYC associated factor X. (166 aa)
WEE2Wee1-like protein kinase. (567 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
H0XPR2_OTOGADIRP domain-containing protein. (496 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
H0XS38_OTOGAF-box domain-containing protein. (410 aa)
E2F1E2F transcription factor 1. (385 aa)
H0XTC3_OTOGADIRP domain-containing protein. (496 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (321 aa)
H0XU64_OTOGABHLH domain-containing protein. (146 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
PSME1Proteasome activator subunit 1. (249 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
H0XZ85_OTOGACyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
PSME2Uncharacterized protein. (239 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.