STRINGSTRING
PSMD1 PSMD1 SPI1 SPI1 SPIB SPIB LMO1 LMO1 GATA2 GATA2 PSMA5 PSMA5 PSMB8 PSMB8 PSMB9 PSMB9 LMO2 LMO2 PSMF1 PSMF1 PSMD7 PSMD7 PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 PSMB10 PSMB10 MNAT1 MNAT1 LDB1 LDB1 LOC100940682 LOC100940682 LOC100942503-4 LOC100942503-4 LOC100942503-5 LOC100942503-5 LOC105888222-3 LOC105888222-3 TAL1 TAL1 LOC100963968 LOC100963968 ITCH ITCH PSMA2 PSMA2 LOC100962662 LOC100962662 LOC100942503-6 LOC100942503-6 H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 H0XIX9_OTOGA H0XIX9_OTOGA LOC100957578 LOC100957578 H0XJC9_OTOGA H0XJC9_OTOGA LOC105888222-4 LOC105888222-4 H0XLJ0_OTOGA H0XLJ0_OTOGA H0XLK2_OTOGA H0XLK2_OTOGA LOC100958180 LOC100958180 LOC100945692 LOC100945692 LOC100942503-8 LOC100942503-8 H2BC1 H2BC1 LOC100961925 LOC100961925 H2BC11 H2BC11 LOC100941637-2 LOC100941637-2 LOC100957578-2 LOC100957578-2 H2AX H2AX LOC100942503-9 LOC100942503-9 H0XRI3_OTOGA H0XRI3_OTOGA H2AZ2 H2AZ2 LOC105888222 LOC105888222 LOC100944154 LOC100944154 H0XTG3_OTOGA H0XTG3_OTOGA MYB MYB PSMA3 PSMA3 PSMA7 PSMA7 PSMB2 PSMB2 LDB2 LDB2 PSMD4 PSMD4 YAP1 YAP1 PSMD13 PSMD13 H2AZ1 H2AZ1 PSMB7 PSMB7 TCF3 TCF3 PSMB4 PSMB4 PSMD8 PSMD8 CBFB CBFB PSMD14 PSMD14 PSMB5 PSMB5 PSMC2 PSMC2 LOC100945040 LOC100945040 TP73 TP73 LOC100959075 LOC100959075 H2BC21 H2BC21 H2AC20 H2AC20 PSMD10 PSMD10 TCF12 TCF12 H0WUK3_OTOGA H0WUK3_OTOGA PSMC4 PSMC4 H0WXD6_OTOGA H0WXD6_OTOGA GATA1 GATA1 LOC100945989 LOC100945989 H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 H0XUT0_OTOGA H0XUT0_OTOGA LOC100942189-2 LOC100942189-2 H0XV82_OTOGA H0XV82_OTOGA H0XVD2_OTOGA H0XVD2_OTOGA LMO3 LMO3 LOC100962662-2 LOC100962662-2 LOC100944801 LOC100944801 LOC100966022 LOC100966022 LOC105888222-5 LOC105888222-5 H0XX44_OTOGA H0XX44_OTOGA H0XX75_OTOGA H0XX75_OTOGA PSME1 PSME1 H0XYI8_OTOGA H0XYI8_OTOGA H2AC6 H2AC6 PSME2 PSME2 LOC100946065 LOC100946065 LOC105888222-6 LOC105888222-6 PSMB11 PSMB11 LOC100942503 LOC100942503 LOC100941637 LOC100941637 H2BC5 H2BC5 LOC100940363 LOC100940363 H0WXI2_OTOGA H0WXI2_OTOGA LOC100942189 LOC100942189 LOC105888222-2 LOC105888222-2 LOC100958063 LOC100958063 H4C8 H4C8 PSMC5 PSMC5 PSMA6 PSMA6 PSMB3 PSMB3 H0X0D7_OTOGA H0X0D7_OTOGA PSME3 PSME3 PSMB6 PSMB6 PSMD5 PSMD5 PSMC6 PSMC6 PSME4 PSME4 CCNH CCNH PSMA4 PSMA4 CDK7 CDK7 PSMD3 PSMD3 PSMA8 PSMA8 PSMB1 PSMB1 GATA3 GATA3 PSMD12 PSMD12 PSMA1 PSMA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
SPIBETS domain-containing protein. (255 aa)
LMO1LIM domain only 1. (156 aa)
GATA2GATA binding protein 2. (480 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
LMO2LIM domain only 2. (222 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD7MPN domain-containing protein. (324 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
PSMB10Proteasome subunit beta. (273 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (285 aa)
LDB1LIM domain binding 1. (356 aa)
LOC100940682Histone H2B type 1. (126 aa)
LOC100942503-4Histone H4. (103 aa)
LOC100942503-5Histone H4. (103 aa)
LOC105888222-3Histone H3.1. (136 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (183 aa)
LOC100963968Uncharacterized protein. (244 aa)
ITCHE3 ubiquitin-protein ligase. (853 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC100962662Histone H3. (136 aa)
LOC100942503-6Histone H4. (103 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XIX9_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100957578Histone H2B type 2-E. (126 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
LOC105888222-4Histone H3.1. (136 aa)
H0XLJ0_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (122 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
LOC100958180Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100945692Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100942503-8Histone H4. (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (136 aa)
LOC100961925Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100941637-2Histone H2B type 1. (126 aa)
LOC100957578-2Histone H2B type 2-E. (126 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC100942503-9Histone H4. (103 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (127 aa)
LOC105888222Histone H3.1. (136 aa)
LOC100944154Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XTG3_OTOGAHistone domain-containing protein. (135 aa)
MYBMYB proto-oncogene, transcription factor. (778 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMB2Proteasome subunit beta. (202 aa)
LDB2LIM domain binding 2. (373 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
YAP1Yes associated protein 1. (501 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMB7Proteasome subunit beta. (277 aa)
TCF3Transcription factor 3. (666 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
CBFBCore-binding factor subunit beta. (185 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
LOC100945040Histone H3; Belongs to the histone H3 family. (136 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (642 aa)
LOC100959075Histone H3; Belongs to the histone H3 family. (136 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
TCF12Transcription factor 12. (506 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
H0WXD6_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
GATA1GATA binding protein 1. (413 aa)
LOC100945989Histone H2B; Belongs to the histone H2B family. (135 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
LOC100942189-2Histone H2A type 1-B/E. (130 aa)
H0XV82_OTOGAHistone domain-containing protein. (84 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LMO3LIM domain only 3. (166 aa)
LOC100962662-2Histone H3. (136 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
LOC100966022Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC105888222-5Histone H3.1. (136 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
PSME1Proteasome activator subunit 1. (249 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
PSME2Uncharacterized protein. (239 aa)
LOC100946065Histone H3.3. (136 aa)
LOC105888222-6Histone H3.1. (136 aa)
PSMB11Proteasome subunit beta. (300 aa)
LOC100942503Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100941637Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100940363Histone H2A; Belongs to the histone H2A family. (130 aa)
H0WXI2_OTOGAHistone H2B; Belongs to the histone H2B family. (135 aa)
LOC100942189Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105888222-2Histone H3.1. (136 aa)
LOC100958063Histone H3.1. (136 aa)
H4C8Histone H4. (103 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB3Proteasome subunit beta. (210 aa)
H0X0D7_OTOGAHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3893 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMB1Proteasome subunit beta. (235 aa)
GATA3GATA binding protein 3. (445 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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