24 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RB1	RB transcriptional corepressor 1. (929 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	ZNF423	Zinc finger protein 423. (1075 aa)
	SP9	Sp9 transcription factor. (482 aa)
	MAF	BZIP domain-containing protein; Belongs to the bZIP family. (153 aa)
	HES6	Hes family bHLH transcription factor 6. (226 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (336 aa)
	BGLAP	Osteocalcin; Binds strongly to apatite and calcium. (100 aa)
	UCMA	Upper zone of growth plate and cartilage matrix associated. (138 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	SP7	Sp7 transcription factor. (431 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	AR	Androgen receptor. (897 aa)
	HDAC6	Histone deacetylase 6. (1210 aa)
	GLI3	GLI family zinc finger 3. (1462 aa)
	MAPK1	Mitogen-activated protein kinase. (323 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	ZNF521	Zinc finger protein 521. (1311 aa)
	CBFB	Core-binding factor subunit beta. (185 aa)
	YES1	Tyrosine-protein kinase. (534 aa)
	YAP1	Yes associated protein 1. (501 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (434 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	HDAC3	ENSOGAP00000013827	ENSOGAP00000000543	Androgen receptor.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.648
AR	RB1	ENSOGAP00000013827	ENSOGAP00000006677	Androgen receptor.	RB transcriptional corepressor 1.	0.668
AR	SRC	ENSOGAP00000013827	ENSOGAP00000013887	Androgen receptor.	Tyrosine-protein kinase.	0.856
AR	YAP1	ENSOGAP00000013827	ENSOGAP00000002584	Androgen receptor.	Yes associated protein 1.	0.455
AR	YES1	ENSOGAP00000013827	ENSOGAP00000003013	Androgen receptor.	Tyrosine-protein kinase.	0.748
BGLAP	CBFB	ENSOGAP00000018077	ENSOGAP00000004037	Osteocalcin; Binds strongly to apatite and calcium.	Core-binding factor subunit beta.	0.572
BGLAP	COL1A1	ENSOGAP00000018077	ENSOGAP00000017068	Osteocalcin; Binds strongly to apatite and calcium.	Collagen type I alpha 1 chain.	0.522
BGLAP	WWTR1	ENSOGAP00000018077	ENSOGAP00000022198	Osteocalcin; Binds strongly to apatite and calcium.	WW domain containing transcription regulator 1.	0.556
BGLAP	YAP1	ENSOGAP00000018077	ENSOGAP00000002584	Osteocalcin; Binds strongly to apatite and calcium.	Yes associated protein 1.	0.502
CBFB	BGLAP	ENSOGAP00000004037	ENSOGAP00000018077	Core-binding factor subunit beta.	Osteocalcin; Binds strongly to apatite and calcium.	0.572
CBFB	WWTR1	ENSOGAP00000004037	ENSOGAP00000022198	Core-binding factor subunit beta.	WW domain containing transcription regulator 1.	0.650
CBFB	YAP1	ENSOGAP00000004037	ENSOGAP00000002584	Core-binding factor subunit beta.	Yes associated protein 1.	0.650
COL1A1	BGLAP	ENSOGAP00000017068	ENSOGAP00000018077	Collagen type I alpha 1 chain.	Osteocalcin; Binds strongly to apatite and calcium.	0.522
COL1A1	SP7	ENSOGAP00000017068	ENSOGAP00000016137	Collagen type I alpha 1 chain.	Sp7 transcription factor.	0.425
HDAC3	AR	ENSOGAP00000000543	ENSOGAP00000013827	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Androgen receptor.	0.648
HDAC3	HDAC6	ENSOGAP00000000543	ENSOGAP00000012420	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 6.	0.725
HDAC3	RB1	ENSOGAP00000000543	ENSOGAP00000006677	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RB transcriptional corepressor 1.	0.916
HDAC3	ZNF423	ENSOGAP00000000543	ENSOGAP00000021446	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Zinc finger protein 423.	0.667
HDAC3	ZNF521	ENSOGAP00000000543	ENSOGAP00000006437	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Zinc finger protein 521.	0.680
HDAC6	HDAC3	ENSOGAP00000012420	ENSOGAP00000000543	Histone deacetylase 6.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.725