STRINGSTRING
PSMA7 PSMA7 PSMD5 PSMD5 PSMC6 PSMC6 NOTCH4 NOTCH4 PSMA4 PSMA4 PSMD3 PSMD3 JAG1 JAG1 CRB1 CRB1 PSMB1 PSMB1 PSMD12 PSMD12 PSMA1 PSMA1 FBXW7 FBXW7 PSMD1 PSMD1 MAMLD1 MAMLD1 PSMA5 PSMA5 PSMB8 PSMB8 PSMB9 PSMB9 SMAD3 SMAD3 PSMF1 PSMF1 CUL1 CUL1 PSMD7 PSMD7 TACC3 TACC3 NOTCH2 NOTCH2 PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA PSMD11 PSMD11 PSMB10 PSMB10 LOC100963968 LOC100963968 KAT2B KAT2B PSMA2 PSMA2 PSEN2 PSEN2 RBX1 RBX1 APH1B APH1B H0XI59_OTOGA H0XI59_OTOGA H0XI75_OTOGA H0XI75_OTOGA H0XJC9_OTOGA H0XJC9_OTOGA SKP1 SKP1 AKT1 AKT1 HES6 HES6 H0XRI3_OTOGA H0XRI3_OTOGA PSMD9 PSMD9 H0XUT0_OTOGA H0XUT0_OTOGA H0XVD2_OTOGA H0XVD2_OTOGA LOC100944801 LOC100944801 MAML1 MAML1 LOC100953470 LOC100953470 H0XX75_OTOGA H0XX75_OTOGA PSME1 PSME1 SNW1 SNW1 H0XYF5_OTOGA H0XYF5_OTOGA H0XYI8_OTOGA H0XYI8_OTOGA PSME2 PSME2 HEY2 HEY2 HES1 HES1 HES5 HES5 KAT2A KAT2A PSME3 PSME3 PSMB3 PSMB3 PSMA6 PSMA6 PSMC5 PSMC5 RBPJ RBPJ HEY1 HEY1 PSMC4 PSMC4 H0WUK3_OTOGA H0WUK3_OTOGA PSMD10 PSMD10 PSMC2 PSMC2 PSMB5 PSMB5 PSMD14 PSMD14 APH1A APH1A ADAM10 ADAM10 PSENEN PSENEN PSMD8 PSMD8 PSMB4 PSMB4 PSMB7 PSMB7 PSMD13 PSMD13 PSMD4 PSMD4 CREBBP CREBBP PSMB2 PSMB2 FLT4 FLT4 NCSTN NCSTN DLL4 DLL4 PSMB6 PSMB6 EP300 EP300 PSMA3 PSMA3 MAML2 MAML2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD5Uncharacterized protein. (504 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
NOTCH4Notch receptor 4. (2000 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CRB1Crumbs cell polarity complex component 1. (1334 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
FBXW7F-box and WD repeat domain containing 7. (379 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
MAMLD1Mastermind like domain containing 1. (744 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD7MPN domain-containing protein. (324 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (753 aa)
NOTCH2Notch receptor 2. (2432 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
PSMB10Proteasome subunit beta. (273 aa)
LOC100963968Uncharacterized protein. (244 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (793 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (451 aa)
RBX1Ring-box 1. (108 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
H0XI59_OTOGA14_3_3 domain-containing protein. (62 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HES6Hes family bHLH transcription factor 6. (226 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
PSMD9PDZ domain-containing protein. (223 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
MAML1Mastermind like transcriptional coactivator 1. (1012 aa)
LOC10095347014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
PSME1Proteasome activator subunit 1. (249 aa)
SNW1SNW domain containing 1. (536 aa)
H0XYF5_OTOGA14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (165 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
PSME2Uncharacterized protein. (239 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HES5Hes family bHLH transcription factor 5. (159 aa)
KAT2ALysine acetyltransferase 2A. (838 aa)
PSME3Proteasome activator subunit 3. (254 aa)
PSMB3Proteasome subunit beta. (210 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (486 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
CREBBPCREB binding protein. (2443 aa)
PSMB2Proteasome subunit beta. (202 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
NCSTNNicastrin. (709 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PSMB6Proteasome subunit beta. (239 aa)
EP300E1A binding protein p300. (2420 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
MAML2Mastermind like transcriptional coactivator 2. (1113 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.