15 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	CLCN2	Chloride channel protein. (906 aa)
	CBS	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (567 aa)
	CLCN7	Chloride channel protein. (805 aa)
	LOC100942563	Chloride channel protein. (687 aa)
	CLCN5	Chloride channel protein. (816 aa)
	PRKAG3	Protein kinase AMP-activated non-catalytic subunit gamma 3. (488 aa)
	CLCN3	Chloride channel protein. (866 aa)
	PRKAG2	Protein kinase AMP-activated non-catalytic subunit gamma 2. (414 aa)
	IMPDH1	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa)
	H0X934_OTOGA	Uncharacterized protein. (318 aa)
	CLCN4	Chloride channel protein. (769 aa)
	IMPDH2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
	CNNM1	Cyclin and CBS domain divalent metal cation transport mediator 1. (952 aa)
	H0XUG1_OTOGA	Uncharacterized protein. (335 aa)
	CLCN6	Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (872 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBS	CNNM1	ENSOGAP00000017619	ENSOGAP00000021187	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Cyclin and CBS domain divalent metal cation transport mediator 1.	0.447
CBS	H0X934_OTOGA	ENSOGAP00000017619	ENSOGAP00000012038	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.773
CBS	H0XUG1_OTOGA	ENSOGAP00000017619	ENSOGAP00000019753	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.773
CBS	PRKAG2	ENSOGAP00000017619	ENSOGAP00000007749	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.761
CBS	PRKAG3	ENSOGAP00000017619	ENSOGAP00000003749	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.759
CLCN2	LOC100942563	ENSOGAP00000018900	ENSOGAP00000006413	Chloride channel protein.	Chloride channel protein.	0.461
CLCN3	CLCN5	ENSOGAP00000007164	ENSOGAP00000006447	Chloride channel protein.	Chloride channel protein.	0.541
CLCN5	CLCN3	ENSOGAP00000006447	ENSOGAP00000007164	Chloride channel protein.	Chloride channel protein.	0.541
CNNM1	CBS	ENSOGAP00000021187	ENSOGAP00000017619	Cyclin and CBS domain divalent metal cation transport mediator 1.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.447
CNNM1	IMPDH1	ENSOGAP00000021187	ENSOGAP00000008761	Cyclin and CBS domain divalent metal cation transport mediator 1.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.437
CNNM1	IMPDH2	ENSOGAP00000021187	ENSOGAP00000003512	Cyclin and CBS domain divalent metal cation transport mediator 1.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.437
H0X934_OTOGA	CBS	ENSOGAP00000012038	ENSOGAP00000017619	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.773
H0X934_OTOGA	IMPDH1	ENSOGAP00000012038	ENSOGAP00000008761	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.506
H0X934_OTOGA	IMPDH2	ENSOGAP00000012038	ENSOGAP00000003512	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.506
H0X934_OTOGA	PRKAG2	ENSOGAP00000012038	ENSOGAP00000007749	Uncharacterized protein.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.881
H0X934_OTOGA	PRKAG3	ENSOGAP00000012038	ENSOGAP00000003749	Uncharacterized protein.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.793
H0XUG1_OTOGA	CBS	ENSOGAP00000019753	ENSOGAP00000017619	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.773
H0XUG1_OTOGA	IMPDH1	ENSOGAP00000019753	ENSOGAP00000008761	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.506
H0XUG1_OTOGA	IMPDH2	ENSOGAP00000019753	ENSOGAP00000003512	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.506
H0XUG1_OTOGA	PRKAG2	ENSOGAP00000019753	ENSOGAP00000007749	Uncharacterized protein.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.881