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AOX4 AOX4 HIBADH HIBADH ACAD10 ACAD10 BCKDHB BCKDHB MCCC1 MCCC1 TNPO1 TNPO1 HMGCS2 HMGCS2 ACSF3 ACSF3 AGXT2 AGXT2 TTLL12 TTLL12 ALDH7A1 ALDH7A1 HSD17B10 HSD17B10 ALDH6A1 ALDH6A1 MCEE MCEE SETD3 SETD3 DLD DLD HADH HADH ALDH16A1 ALDH16A1 ECHS1 ECHS1 IL4I1 IL4I1 H0WS29_OTOGA H0WS29_OTOGA HADHB HADHB DBT DBT AOX1 AOX1 H0WTP3_OTOGA H0WTP3_OTOGA ACAA1 ACAA1 EHHADH EHHADH PCCB PCCB ACAT2 ACAT2 ACADM ACADM ACADS ACADS ACADSB ACADSB MCCC2 MCCC2 CARTPT CARTPT HMGCS1 HMGCS1 HMGCL HMGCL IVD IVD OXCT1 OXCT1 AACS AACS AUH AUH TNPO2 TNPO2 BCAT2 BCAT2 HMGCLL1 HMGCLL1 ECHDC2 ECHDC2 BCAT1 BCAT1 ACAD8 ACAD8 H0XEL1_OTOGA H0XEL1_OTOGA ACAA2 ACAA2 ABAT ABAT SETD4 SETD4 ALDH3A2 ALDH3A2 PCCA PCCA ACAT1 ACAT1 MMUT MMUT HSD17B14 HSD17B14 ACAD11 ACAD11 H0XPC1_OTOGA H0XPC1_OTOGA H0XQA8_OTOGA H0XQA8_OTOGA ALDH2 ALDH2 H0XWY3_OTOGA H0XWY3_OTOGA HIBCH HIBCH AOX2 AOX2 ALDH1B1 ALDH1B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOX4Uncharacterized protein. (1336 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1059 aa)
BCKDHBTransket_pyr domain-containing protein. (327 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (654 aa)
TNPO1Transportin 1. (898 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ACSF3Acyl-CoA synthetase family member 3. (576 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
TTLL12Tubulin tyrosine ligase like 12. (645 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (540 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (520 aa)
MCEEMethylmalonyl-CoA epimerase. (176 aa)
SETD3Actin-histidine N-methyltransferase; Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. (595 aa)
DLDDihydrolipoamide dehydrogenase. (461 aa)
HADHHydroxyacyl-CoA dehydrogenase. (314 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (753 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
IL4I1Amine oxidase. (531 aa)
H0WS29_OTOGA3HCDH_N domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. (412 aa)
HADHBUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
AOX1Uncharacterized protein. (1340 aa)
H0WTP3_OTOGAUncharacterized protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (725 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (539 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (454 aa)
ACADSAcyl-CoA dehydrogenase short chain. (414 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (433 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (564 aa)
CARTPTCART prepropeptide. (116 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (524 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
AACSAcetoacetyl-CoA synthetase. (674 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (336 aa)
TNPO2Transportin 2. (1038 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (392 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (237 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (296 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (386 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (413 aa)
H0XEL1_OTOGA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (454 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ABATUncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
SETD4SET domain containing 4. (440 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
MMUTMethylmalonyl-CoA mutase. (755 aa)
HSD17B14Hydroxysteroid 17-beta dehydrogenase 14. (270 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
H0XPC1_OTOGATransket_pyr domain-containing protein. (319 aa)
H0XQA8_OTOGAUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
H0XWY3_OTOGAUncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (215 aa)
AOX2Uncharacterized protein. (1351 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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