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| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (867 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (193 aa) |
| | H0WK58_OTOGA | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | CDC20 | Cell division cycle 20. (500 aa) |
| | CHEK1 | Checkpoint kinase 1. (449 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | ZBTB46 | Zinc finger and BTB domain containing 46. (587 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | ZBTB17 | Zinc finger and BTB domain containing 17. (795 aa) |
| | MYNN | Myoneurin. (610 aa) |
| | E2F3 | E2F transcription factor 3. (463 aa) |
| | LOC100957931 | HORMA domain-containing protein. (205 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (Predicted); Belongs to the 14-3-3 family. (246 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (254 aa) |
| | H0XZI5_OTOGA | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) |
| | H0XZ50_OTOGA | Uncharacterized protein; Belongs to the cyclin family. (375 aa) |
| | H0XYF5_OTOGA | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (165 aa) |
| | CDC45 | Cell division cycle 45. (616 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (493 aa) |
| | DBF4 | DBF4 zinc finger. (678 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | LOC100953470 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) |
| | H0XWX5_OTOGA | Wee1-like protein kinase. (561 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | CHEK2 | Checkpoint kinase 2. (544 aa) |
| | ZBTB47 | Zinc finger and BTB domain containing 47. (576 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1236 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | ZNF652 | Zinc finger protein 652. (610 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1301 aa) |
| | CDC25A | Cell division cycle 25A. (525 aa) |
| | SNPH | Syntaphilin. (494 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1238 aa) |
| | CREBBP | CREB binding protein. (2443 aa) |
| | E2F4 | E2F transcription factor 4. (403 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (717 aa) |
| | TFDP2 | Transcription factor. (426 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2642 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4081 aa) |
| | LOC100943441 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (321 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa) |
| | ANAPC13 | Anaphase promoting complex subunit 13. (74 aa) |
| | E2F1 | E2F transcription factor 1. (385 aa) |
| | H0XS38_OTOGA | F-box domain-containing protein. (410 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (324 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | H0XQC2_OTOGA | Uncharacterized protein; Belongs to the cyclin family. (426 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | ZBTB10 | Zinc finger and BTB domain containing 10. (872 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | CDC7 | Cell division cycle 7. (576 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | H0XL98_OTOGA | Uncharacterized protein. (475 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | LOC100944047 | Uncharacterized protein; Belongs to the cyclin family. (427 aa) |
| | H0XJL1_OTOGA | Uncharacterized protein; Belongs to the cyclin family. (367 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A. (205 aa) |
| | H0XIE5_OTOGA | Uncharacterized protein. (203 aa) |
| | H0XI59_OTOGA | 14_3_3 domain-containing protein. (62 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3051 aa) |
| | H0XGN3_OTOGA | Uncharacterized protein. (622 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | ORC3 | Origin recognition complex subunit 3. (672 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | CDC27 | Cell division cycle 27. (826 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (791 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | ORC1 | Origin recognition complex subunit 1. (727 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (554 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (906 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (565 aa) |
| | E2F5 | E2F transcription factor 5. (347 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | FAM126B | Family with sequence similarity 126 member B. (531 aa) |
| | ORC2 | Origin recognition complex subunit 2. (580 aa) |
| | H0X6L5_OTOGA | Uncharacterized protein. (201 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | E2F2 | E2F transcription factor 2. (438 aa) |
| | H0X5M8_OTOGA | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) |
| | WEE1 | Wee1-like protein kinase. (643 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (328 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (422 aa) |
| | TTK | TTK protein kinase. (856 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (131 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | CDC16 | Cell division cycle 16. (553 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (323 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (426 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | CDC14A | Cell division cycle 14A. (622 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (2118 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | CDC25C | Cell division cycle 25C. (467 aa) |
| | YWHAB | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (822 aa) |
| | CDK20 | Cyclin dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa) |
| | PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (489 aa) |
| | TMEM82 | Transmembrane protein 82. (346 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | BUB1B | Uncharacterized protein. (1039 aa) |
| | AP5S1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | CDC25B | Cell division cycle 25B. (514 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (156 aa) |
| | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1085 aa) |
| | CDC14B | Uncharacterized protein. (444 aa) |
| | RB1 | RB transcriptional corepressor 1. (929 aa) |
| | SKP2 | F-box domain-containing protein. (424 aa) |
| | CDC20B | Cell division cycle 20B. (477 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | STAG1 | Stromal antigen 1. (1161 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta. (387 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (834 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
