STRINGSTRING
PIAS3 PIAS3 HERC2 HERC2 NOC4L NOC4L PIAS4 PIAS4 KBTBD2 KBTBD2 KLHL21 KLHL21 UBE2I UBE2I CUL4B CUL4B UBE2Z UBE2Z SIAH1 SIAH1 SIAH3 SIAH3 LOC100951173 LOC100951173 BORCS5 BORCS5 LOC100945306 LOC100945306 KBTBD12 KBTBD12 H0XJL7_OTOGA H0XJL7_OTOGA SKP1 SKP1 PLEKHA4 PLEKHA4 H0XJA1_OTOGA H0XJA1_OTOGA H0XIX1_OTOGA H0XIX1_OTOGA KLHL9 KLHL9 LOC100951568 LOC100951568 UBA52 UBA52 H0XI83_OTOGA H0XI83_OTOGA FBXO24 FBXO24 PPIL2 PPIL2 H0XHC8_OTOGA H0XHC8_OTOGA H0XH70_OTOGA H0XH70_OTOGA HERC5 HERC5 HERC6 HERC6 CUL4A CUL4A UBE3A UBE3A RBX1 RBX1 ITCH ITCH PRPF19 PRPF19 UBE2B UBE2B IVNS1ABP IVNS1ABP DDB1 DDB1 FANCL FANCL KLHL22 KLHL22 CDC27 CDC27 NEDD4L NEDD4L UBA1 UBA1 COP1 COP1 SMURF2 SMURF2 KLHL14 KLHL14 UBE3B UBE3B UBE2E3 UBE2E3 MID1 MID1 RHOBTB2 RHOBTB2 H0XBX0_OTOGA H0XBX0_OTOGA CUL1 CUL1 BTRC BTRC UBA6 UBA6 FBXL12 FBXL12 H0XBB0_OTOGA H0XBB0_OTOGA KLHL1 KLHL1 KLHL13 KLHL13 FZR1 FZR1 PIAS1 PIAS1 PDCD2 PDCD2 NEDD4 NEDD4 FLYWCH1 FLYWCH1 UBE2QL1 UBE2QL1 LOC100951719 LOC100951719 UBE2R2 UBE2R2 H0XLJ8_OTOGA H0XLJ8_OTOGA KLHL35 KLHL35 H0XM85_OTOGA H0XM85_OTOGA H0XMA4_OTOGA H0XMA4_OTOGA KBTBD13 KBTBD13 KLHL15 KLHL15 H0XMK6_OTOGA H0XMK6_OTOGA KLHL25 KLHL25 UBE2O UBE2O SOCS3 SOCS3 SYVN1 SYVN1 WDR76 WDR76 KLHL40 KLHL40 DBN1 DBN1 PLEKHA7 PLEKHA7 LOC100949391 LOC100949391 H0XPA8_OTOGA H0XPA8_OTOGA FBXL14 FBXL14 H0XPJ8_OTOGA H0XPJ8_OTOGA H0XPU8_OTOGA H0XPU8_OTOGA CDC26 CDC26 UBE2D1 UBE2D1 ALKBH4 ALKBH4 H0XQF7_OTOGA H0XQF7_OTOGA ERCC8 ERCC8 H0XQT8_OTOGA H0XQT8_OTOGA CFAP300 CFAP300 KBTBD8 KBTBD8 KLHL24 KLHL24 H0XS38_OTOGA H0XS38_OTOGA H0XSF2_OTOGA H0XSF2_OTOGA H0XSH6_OTOGA H0XSH6_OTOGA NHLRC1 NHLRC1 KLHL38 KLHL38 BTBD6 BTBD6 ANAPC13 ANAPC13 H0XTI2_OTOGA H0XTI2_OTOGA H0XTJ2_OTOGA H0XTJ2_OTOGA LOC100943149 LOC100943149 H0XTR4_OTOGA H0XTR4_OTOGA KLHL17 KLHL17 H0XUE4_OTOGA H0XUE4_OTOGA CNFN CNFN FBXL6 FBXL6 FBXO16 FBXO16 H0XVC6_OTOGA H0XVC6_OTOGA H0XVR1_OTOGA H0XVR1_OTOGA WDR86 WDR86 H0XVS5_OTOGA H0XVS5_OTOGA H0XVW7_OTOGA H0XVW7_OTOGA UBE2A UBE2A KLHL11 KLHL11 H0XW17_OTOGA H0XW17_OTOGA BIRC7 BIRC7 FBXL15 FBXL15 KLHDC7A KLHDC7A RCHY1 RCHY1 FAM89B FAM89B KBTBD4 KBTBD4 H0XX44_OTOGA H0XX44_OTOGA H0XXA4_OTOGA H0XXA4_OTOGA ANAPC1 ANAPC1 UBOX5 UBOX5 H0XXJ8_OTOGA H0XXJ8_OTOGA SOCS1 SOCS1 MDM2 MDM2 ELOC ELOC ANAPC11 ANAPC11 BTBD17 BTBD17 SAE1 SAE1 UBE2D4 UBE2D4 CCIN CCIN LOC100945371 LOC100945371 H0Y0B7_OTOGA H0Y0B7_OTOGA H0Y0U3_OTOGA H0Y0U3_OTOGA LOC100956001 LOC100956001 H0Y1C5_OTOGA H0Y1C5_OTOGA H0Y1D8_OTOGA H0Y1D8_OTOGA H0Y1G8_OTOGA H0Y1G8_OTOGA KLHL34 KLHL34 KBTBD11 KBTBD11 HMGN1 HMGN1 H0Y1K4_OTOGA H0Y1K4_OTOGA KCTD2 KCTD2 KBTBD7 KBTBD7 H0Y277_OTOGA H0Y277_OTOGA TRIM32 TRIM32 H0Y2I7_OTOGA H0Y2I7_OTOGA CUL7 CUL7 PIAS2 PIAS2 HERC4 HERC4 KEAP1 KEAP1 GAN GAN DDB2 DDB2 FBXW8 FBXW8 KLHL5 KLHL5 FBXW9 FBXW9 TRIM37 TRIM37 WWP1 WWP1 CUL3 CUL3 FBXO2 FBXO2 UBE2G2 UBE2G2 FBXW11 FBXW11 H0X5M8_OTOGA H0X5M8_OTOGA FBXW7 FBXW7 CBLB CBLB KRT8 KRT8 UBE4B UBE4B HACE1 HACE1 PRKN PRKN MID2 MID2 UBE2Q1 UBE2Q1 AIRE AIRE CDC16 CDC16 KLHL42 KLHL42 UBA7 UBA7 BIRC2 BIRC2 TRIM42 TRIM42 SMURF1 SMURF1 FBXW2 FBXW2 CGRRF1 CGRRF1 HECTD3 HECTD3 KLHL8 KLHL8 UBE2J1 UBE2J1 LOC100962144 LOC100962144 KLHL36 KLHL36 UBE4A UBE4A KLHL2 KLHL2 KBTBD3 KBTBD3 ENC1 ENC1 UBA2 UBA2 H0WZC1_OTOGA H0WZC1_OTOGA UBE2E2 UBE2E2 KLHL18 KLHL18 UBE2G1 UBE2G1 RNF7 RNF7 STOML2 STOML2 UBE2U UBE2U UBE2K UBE2K NPHS2 NPHS2 FBXL17 FBXL17 UBA3 UBA3 H0WWM1_OTOGA H0WWM1_OTOGA UBE2E1 UBE2E1 TRAF6 TRAF6 RNF26 RNF26 CBL CBL SKP2 SKP2 CUL5 CUL5 CDC20B CDC20B PML PML STOML1 STOML1 PMEL PMEL KLHL28 KLHL28 ANAPC10 ANAPC10 CBLC CBLC CACUL1 CACUL1 DBNL DBNL NECAP1 NECAP1 STOML3 STOML3 HECTD2 HECTD2 BIRC6 BIRC6 KCTD17 KCTD17 BIRC3 BIRC3 ANAPC2 ANAPC2 INTU INTU PRC1 PRC1 UBE2M UBE2M UBE2F UBE2F H0WRQ7_OTOGA H0WRQ7_OTOGA NECAP2 NECAP2 CUL2 CUL2 H0WR29_OTOGA H0WR29_OTOGA FAM89A FAM89A KLHL26 KLHL26 H0WQK6_OTOGA H0WQK6_OTOGA CDC34 CDC34 WWP2 WWP2 KLHL29 KLHL29 UBE2L6 UBE2L6 UBR5 UBR5 UBE2Q2 UBE2Q2 KLHL32 KLHL32 IPP IPP KLHL20 KLHL20 KLHDC8B KLHDC8B UBE2S UBE2S KCTD5 KCTD5 STUB1 STUB1 KLHL23 KLHL23 H0WNB4_OTOGA H0WNB4_OTOGA CDC23 CDC23 RNF157 RNF157 HERC3 HERC3 FBXL7 FBXL7 HECW2 HECW2 SIAH2 SIAH2 H0WLN2_OTOGA H0WLN2_OTOGA AREL1 AREL1 MAP3K1 MAP3K1 SLC35E3 SLC35E3 TRIP12 TRIP12 ANAPC4 ANAPC4 FBXO4 FBXO4 C5orf51 C5orf51 HUWE1 HUWE1 TMEM231 TMEM231 CDC20 CDC20 KLHL30 KLHL30 HECW1 HECW1 ANAPC7 ANAPC7 KLHL33 KLHL33 FBXO7 FBXO7 H0X8M1_OTOGA H0X8M1_OTOGA HERC1 HERC1 KLHDC8A KLHDC8A KLHL31 KLHL31 UBE2D3 UBE2D3 KLHL3 KLHL3 H0X7T1_OTOGA H0X7T1_OTOGA DHPS DHPS UBE2H UBE2H UBE3C UBE3C ANAPC5 ANAPC5 KLHL6 KLHL6 RHOBTB1 RHOBTB1 H0WGG6_OTOGA H0WGG6_OTOGA ABTB2 ABTB2 KLHL10 KLHL10 H0WGF6_OTOGA H0WGF6_OTOGA MGRN1 MGRN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PIAS3Protein inhibitor of activated STAT 3. (621 aa)
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4810 aa)
NOC4LNucleolar complex associated 4 homolog. (522 aa)
PIAS4Protein inhibitor of activated STAT 4. (511 aa)
KBTBD2Kelch repeat and BTB domain containing 2. (627 aa)
KLHL21Kelch like family member 21. (597 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)
CUL4BCullin 4B; Belongs to the cullin family. (889 aa)
UBE2ZUbiquitin conjugating enzyme E2 Z. (356 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
SIAH3E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (267 aa)
LOC100951173E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (283 aa)
BORCS5BLOC-1 related complex subunit 5. (196 aa)
LOC100945306E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
KBTBD12Kelch repeat and BTB domain containing 12. (623 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PLEKHA4Pleckstrin homology domain containing A4. (776 aa)
H0XJA1_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (263 aa)
H0XIX1_OTOGAE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (345 aa)
KLHL9Kelch like family member 9. (629 aa)
LOC100951568PHB domain-containing protein. (285 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
FBXO24F-box protein 24. (609 aa)
PPIL2Peptidylprolyl isomerase like 2. (556 aa)
H0XHC8_OTOGAUncharacterized protein. (464 aa)
H0XH70_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (956 aa)
HERC6HECT and RLD domain containing E3 ubiquitin protein ligase family member 6. (1048 aa)
CUL4ACullin 4A isoform 1 (Predicted); Belongs to the cullin family. (701 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (851 aa)
RBX1Ring-box 1. (108 aa)
ITCHE3 ubiquitin-protein ligase. (853 aa)
PRPF19Pre-mRNA processing factor 19. (506 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
IVNS1ABPInfluenza virus NS1A binding protein. (642 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
FANCLFA complementation group L. (375 aa)
KLHL22Kelch like family member 22. (633 aa)
CDC27Cell division cycle 27. (826 aa)
NEDD4LE3 ubiquitin-protein ligase. (877 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1059 aa)
COP1COP1 E3 ubiquitin ligase. (735 aa)
SMURF2E3 ubiquitin-protein ligase. (732 aa)
KLHL14Kelch like family member 14. (630 aa)
UBE3BUbiquitin protein ligase E3B. (1068 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
MID1Midline 1. (683 aa)
RHOBTB2Rho related BTB domain containing 2. (728 aa)
H0XBX0_OTOGABTB domain-containing protein. (261 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (526 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1052 aa)
FBXL12F-box and leucine rich repeat protein 12. (326 aa)
H0XBB0_OTOGAUncharacterized protein. (100 aa)
KLHL1Kelch like family member 1. (617 aa)
KLHL13Kelch like family member 13. (655 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
PIAS1Protein inhibitor of activated STAT 1. (651 aa)
PDCD2Programmed cell death 2. (344 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1291 aa)
FLYWCH1FLYWCH-type zinc finger 1. (676 aa)
UBE2QL1Ubiquitin conjugating enzyme E2 Q family like 1. (161 aa)
LOC100951719Uncharacterized protein. (598 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (224 aa)
H0XLJ8_OTOGAUncharacterized protein. (77 aa)
KLHL35Kelch like family member 35. (569 aa)
H0XM85_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (492 aa)
H0XMA4_OTOGAIF rod domain-containing protein. (347 aa)
KBTBD13Kelch repeat and BTB domain containing 13. (458 aa)
KLHL15Kelch like family member 15. (604 aa)
H0XMK6_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
KLHL25Kelch like family member 25. (589 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1294 aa)
SOCS3Suppressor of cytokine signaling 3. (224 aa)
SYVN1Synoviolin 1. (611 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (629 aa)
KLHL40Kelch like family member 40. (619 aa)
DBN1Drebrin 1. (657 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1200 aa)
LOC100949391UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
H0XPA8_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein. (148 aa)
FBXL14F-box and leucine rich repeat protein 14. (400 aa)
H0XPJ8_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
H0XPU8_OTOGABTB_2 domain-containing protein. (194 aa)
CDC26Cell division cycle 26. (85 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (302 aa)
H0XQF7_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (363 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (399 aa)
H0XQT8_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (481 aa)
CFAP300Cilia and flagella associated protein 300. (267 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
KLHL24Kelch like family member 24. (602 aa)
H0XS38_OTOGAF-box domain-containing protein. (410 aa)
H0XSF2_OTOGARING-type domain-containing protein. (236 aa)
H0XSH6_OTOGAUncharacterized protein. (100 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
KLHL38Kelch like family member 38. (581 aa)
BTBD6BTB domain containing 6. (538 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
H0XTI2_OTOGARING-type domain-containing protein. (637 aa)
H0XTJ2_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (403 aa)
LOC100943149E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (284 aa)
H0XTR4_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein. (168 aa)
KLHL17Kelch like family member 17. (643 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
CNFNCornifelin. (112 aa)
FBXL6F-box and leucine rich repeat protein 6. (536 aa)
FBXO16F-box protein 16. (309 aa)
H0XVC6_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
H0XVR1_OTOGAUncharacterized protein. (237 aa)
WDR86WD repeat domain 86. (378 aa)
H0XVS5_OTOGAUncharacterized protein. (591 aa)
H0XVW7_OTOGABTB domain-containing protein. (224 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
KLHL11Kelch like family member 11. (684 aa)
H0XW17_OTOGAUncharacterized protein. (150 aa)
BIRC7Baculoviral IAP repeat containing 7. (296 aa)
FBXL15F-box and leucine rich repeat protein 15. (298 aa)
KLHDC7AKelch domain containing 7A. (767 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (252 aa)
FAM89BFamily with sequence similarity 89 member B. (186 aa)
KBTBD4Kelch repeat and BTB domain containing 4. (543 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
H0XXA4_OTOGAUncharacterized protein. (71 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
UBOX5U-box domain containing 5. (472 aa)
H0XXJ8_OTOGAE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (284 aa)
SOCS1Suppressor of cytokine signaling 1. (212 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (493 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (110 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
BTBD17BTB domain containing 17. (478 aa)
SAE1SUMO1 activating enzyme subunit 1. (348 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
CCINCalicin. (588 aa)
LOC100945371E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (288 aa)
H0Y0B7_OTOGAE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (283 aa)
H0Y0U3_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (178 aa)
LOC100956001UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
H0Y1C5_OTOGAPH domain-containing protein. (968 aa)
H0Y1D8_OTOGAE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (256 aa)
H0Y1G8_OTOGASkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
KLHL34Kelch like family member 34. (616 aa)
KBTBD11Kelch repeat and BTB domain containing 11. (617 aa)
HMGN1Uncharacterized protein. (101 aa)
H0Y1K4_OTOGAE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (283 aa)
KCTD2BTB domain-containing protein. (263 aa)
KBTBD7Kelch repeat and BTB domain containing 7. (687 aa)
H0Y277_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (475 aa)
TRIM32Uncharacterized protein. (653 aa)
H0Y2I7_OTOGAIF rod domain-containing protein; Belongs to the intermediate filament family. (344 aa)
CUL7Cullin 7; Belongs to the cullin family. (1726 aa)
PIAS2Protein inhibitor of activated STAT 2. (622 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1057 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
GANGigaxonin. (600 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
FBXW8F-box and WD repeat domain containing 8. (596 aa)
KLHL5Kelch like family member 5. (761 aa)
FBXW9F-box and WD repeat domain containing 9. (448 aa)
TRIM37Tripartite motif containing 37. (963 aa)
WWP1E3 ubiquitin-protein ligase. (924 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
FBXO2F-box protein 2. (292 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2. (84 aa)
FBXW11F-box and WD repeat domain containing 11. (580 aa)
H0X5M8_OTOGAE3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
FBXW7F-box and WD repeat domain containing 7. (379 aa)
CBLBCbl proto-oncogene B. (983 aa)
KRT8IF rod domain-containing protein; Belongs to the intermediate filament family. (491 aa)
UBE4BUbiquitination factor E4B. (1358 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (910 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
MID2Midline 2. (715 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (392 aa)
AIREAutoimmune regulator. (543 aa)
CDC16Cell division cycle 16. (553 aa)
KLHL42Kelch like family member 42. (505 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1004 aa)
BIRC2Uncharacterized protein. (618 aa)
TRIM42Tripartite motif containing 42. (721 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
FBXW2F-box and WD repeat domain containing 2. (460 aa)
CGRRF1Cell growth regulator with ring finger domain 1. (332 aa)
HECTD3HECT domain E3 ubiquitin protein ligase 3. (861 aa)
KLHL8Kelch like family member 8. (621 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (311 aa)
LOC100962144E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
KLHL36Kelch like family member 36. (616 aa)
UBE4AUbiquitination factor E4A. (1075 aa)
KLHL2Kelch like family member 2. (597 aa)
KBTBD3Kelch repeat and BTB domain containing 3. (607 aa)
ENC1Ectodermal-neural cortex 1. (589 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa)
H0WZC1_OTOGAPDCD2_C domain-containing protein. (358 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (126 aa)
KLHL18Kelch like family member 18. (588 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
RNF7Ring finger protein 7. (113 aa)
STOML2Stomatin like 2. (356 aa)
UBE2UUbiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (320 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
NPHS2NPHS2 stomatin family member, podocin. (382 aa)
FBXL17F-box and leucine rich repeat protein 17. (455 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
H0WWM1_OTOGAUncharacterized protein. (221 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (535 aa)
RNF26Ring finger protein 26. (433 aa)
CBLCbl proto-oncogene. (905 aa)
SKP2F-box domain-containing protein. (424 aa)
CUL5Cullin 5; Belongs to the cullin family. (781 aa)
CDC20BCell division cycle 20B. (477 aa)
PMLPromyelocytic leukemia. (874 aa)
STOML1Stomatin like 1. (398 aa)
PMELPremelanosome protein. (670 aa)
KLHL28Kelch like family member 28. (571 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CBLCCbl proto-oncogene C. (472 aa)
CACUL1CDK2 associated cullin domain 1; Belongs to the cullin family. (327 aa)
DBNLDrebrin like. (437 aa)
NECAP1NECAP endocytosis associated 1. (277 aa)
STOML3Stomatin like 3. (291 aa)
HECTD2HECT domain E3 ubiquitin protein ligase 2. (580 aa)
BIRC6Baculoviral IAP repeat containing 6. (4838 aa)
KCTD17Potassium channel tetramerization domain containing 17. (322 aa)
BIRC3Baculoviral IAP repeat containing 3. (605 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (834 aa)
INTUInturned planar cell polarity protein. (938 aa)
PRC1Protein regulator of cytokinesis 1. (620 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
UBE2FUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
H0WRQ7_OTOGASkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
NECAP2NECAP endocytosis associated 2. (274 aa)
CUL2Cullin 2; Belongs to the cullin family. (748 aa)
H0WR29_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
FAM89AFamily with sequence similarity 89 member A. (182 aa)
KLHL26Kelch like family member 26. (590 aa)
H0WQK6_OTOGAUncharacterized protein. (553 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
KLHL29Kelch like family member 29. (653 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2797 aa)
UBE2Q2Ubiquitin conjugating enzyme E2 Q2. (377 aa)
KLHL32Kelch like family member 32. (568 aa)
IPPIntracisternal A particle-promoted polypeptide. (584 aa)
KLHL20Kelch like family member 20. (609 aa)
KLHDC8BKelch domain containing 8B. (354 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (217 aa)
KCTD5Potassium channel tetramerization domain containing 5. (234 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
KLHL23Kelch like family member 23. (559 aa)
H0WNB4_OTOGAUncharacterized protein. (544 aa)
CDC23Cell division cycle 23. (597 aa)
RNF157Ring finger protein 157. (612 aa)
HERC3HECT domain-containing protein. (1050 aa)
FBXL7F-box and leucine rich repeat protein 7. (481 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
H0WLN2_OTOGAPHB domain-containing protein. (264 aa)
AREL1Apoptosis resistant E3 ubiquitin protein ligase 1. (822 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1 (Predicted). (1349 aa)
SLC35E3Solute carrier family 35 member E3. (179 aa)
TRIP12Thyroid hormone receptor interactor 12. (2042 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
FBXO4F-box protein 4. (387 aa)
C5orf51Chromosome 5 open reading frame 51. (294 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4376 aa)
TMEM231Uncharacterized protein. (344 aa)
CDC20Cell division cycle 20. (500 aa)
KLHL30Kelch like family member 30. (578 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1573 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
KLHL33Kelch like family member 33. (533 aa)
FBXO7F-box only protein 7 isoform 1 (Predicted). (518 aa)
H0X8M1_OTOGAUncharacterized protein. (936 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4851 aa)
KLHDC8AKelch domain containing 8A. (350 aa)
KLHL31Kelch like family member 31. (634 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
KLHL3Kelch like family member 3. (589 aa)
H0X7T1_OTOGASkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
DHPSUncharacterized protein. (369 aa)
UBE2HUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
UBE3CUbiquitin protein ligase E3C. (1073 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
KLHL6Kelch like family member 6. (621 aa)
RHOBTB1Rho related BTB domain containing 1. (696 aa)
H0WGG6_OTOGAUBIQUITIN_CONJUGAT_2 domain-containing protein. (275 aa)
ABTB2Ankyrin repeat and BTB domain containing 2. (1026 aa)
KLHL10Kelch like family member 10. (608 aa)
H0WGF6_OTOGABTB domain-containing protein. (645 aa)
MGRN1Mahogunin ring finger 1. (554 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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