STRINGSTRING
ITPR3 ITPR3 GRM7 GRM7 GLUL GLUL LGSN LGSN PLA2G4A PLA2G4A H0XZZ5_OTOGA H0XZZ5_OTOGA GNG8 GNG8 GRIN1 GRIN1 GNG3 GNG3 H0XWN3_OTOGA H0XWN3_OTOGA SLC1A6 SLC1A6 H0XV13_OTOGA H0XV13_OTOGA GNB3 GNB3 GRM6 GRM6 GRM4 GRM4 MAPK3 MAPK3 GNAO1 GNAO1 GNAS GNAS GNG7 GNG7 SHANK1 SHANK1 SHANK2 SHANK2 LOC100966244 LOC100966244 SHANK3 SHANK3 JMJD7 JMJD7 GRIN2C GRIN2C GRM1 GRM1 ADCY6 ADCY6 GRIN2B GRIN2B SLC1A2 SLC1A2 PLA2G4E PLA2G4E H0XEJ2_OTOGA H0XEJ2_OTOGA GRIN3A GRIN3A GRIK5 GRIK5 GNB2 GNB2 ADCY5 ADCY5 GRIA2 GRIA2 GRIN3B GRIN3B PRKCA PRKCA GNAI3 GNAI3 SLC1A7 SLC1A7 DLGAP1 DLGAP1 GLS2 GLS2 GNAI2 GNAI2 SLC38A3 SLC38A3 HOMER1 HOMER1 GRM2 GRM2 PRKACA PRKACA PPP3CA PPP3CA ADCY7 ADCY7 PLA2G4F PLA2G4F PLA2G4D PLA2G4D GRM8 GRM8 CACNA1C CACNA1C GRK2 GRK2 H0X324_OTOGA H0X324_OTOGA PPP3CC PPP3CC GRIA1 GRIA1 PLD1 PLD1 PLCB2 PLCB2 ITPR2 ITPR2 GRIK1 GRIK1 PLD2 PLD2 GRIK2 GRIK2 MAPK1 MAPK1 GRIA4 GRIA4 GNB5 GNB5 HOMER2 HOMER2 PRKCG PRKCG SLC17A8 SLC17A8 SLC1A1 SLC1A1 GNG4 GNG4 PLCB4 PLCB4 PLCB3 PLCB3 PLCB1 PLCB1 GNG2 GNG2 SLC38A2 SLC38A2 SLC38A1 SLC38A1 GRM3 GRM3 ADCY4 ADCY4 PRKACB PRKACB GRIN2D GRIN2D KCNJ3 KCNJ3 GNG11 GNG11 GNGT1 GNGT1 SLC1A3 SLC1A3 GNB1 GNB1 ADCY1 ADCY1 GNG5 GNG5 GNG12 GNG12 DLG4 DLG4 SLC17A6 SLC17A6 GRM5 GRM5 GNG13 GNG13 ITPR1 ITPR1 GRK3 GRK3 GLS GLS ADCY9 ADCY9 PPP3CB PPP3CB GRIK3 GRIK3 CACNA1A CACNA1A GRIK4 GRIK4 ADCY8 ADCY8 PRKCB PRKCB ADCY2 ADCY2 GNB4 GNB4 ADCY3 ADCY3 TRPC1 TRPC1 PTRHD1 PTRHD1 SLC17A7 SLC17A7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2728 aa)
GRM7Glutamate metabotropic receptor 7. (747 aa)
GLULGlutamate-ammonia ligase; Belongs to the glutamine synthetase family. (353 aa)
LGSNLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (572 aa)
PLA2G4APhospholipase A2. (748 aa)
H0XZZ5_OTOGAUncharacterized protein. (174 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
H0XWN3_OTOGAWH1 domain-containing protein. (179 aa)
SLC1A6Amino acid transporter. (566 aa)
H0XV13_OTOGAANF_receptor domain-containing protein. (212 aa)
GNB3G protein subunit beta 3. (340 aa)
GRM6Glutamate metabotropic receptor 6. (868 aa)
GRM4Glutamate metabotropic receptor 4. (912 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (336 aa)
GNAO1G protein subunit alpha o1. (278 aa)
GNASGNAS complex locus. (1146 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2174 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1170 aa)
LOC100966244Uncharacterized protein. (260 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1751 aa)
JMJD7Jumonji domain containing 7. (316 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1248 aa)
GRM1Glutamate metabotropic receptor 1. (906 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1351 aa)
SLC1A2Amino acid transporter. (576 aa)
PLA2G4EPhospholipase A2. (850 aa)
H0XEJ2_OTOGAPhospholipase A2. (807 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (977 aa)
GNB2G protein subunit beta 2. (340 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (836 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1044 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (691 aa)
GNAI3G protein subunit alpha i3. (354 aa)
SLC1A7Amino acid transporter. (574 aa)
DLGAP1DLG associated protein 1. (978 aa)
GLS2Glutaminase 2. (477 aa)
GNAI2G protein subunit alpha i2. (355 aa)
SLC38A3Solute carrier family 38 member 3. (504 aa)
HOMER1Homer scaffold protein 1. (354 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
PLA2G4FPhospholipase A2. (865 aa)
PLA2G4DPhospholipase A2. (829 aa)
GRM8Glutamate metabotropic receptor 8. (910 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
H0X324_OTOGANMDAR2_C domain-containing protein. (426 aa)
PPP3CCSerine/threonine-protein phosphatase. (510 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (867 aa)
PLD1Phospholipase. (1075 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2647 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (677 aa)
PLD2Phospholipase. (1007 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (912 aa)
MAPK1Mitogen-activated protein kinase. (323 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (733 aa)
GNB5G protein subunit beta 5. (397 aa)
HOMER2Homer scaffold protein 2. (364 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
SLC1A1Amino acid transporter. (524 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
SLC38A2Solute carrier family 38 member 2. (506 aa)
SLC38A1Solute carrier family 38 member 1. (487 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1332 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
SLC1A3Amino acid transporter. (542 aa)
GNB1G protein subunit beta 1. (340 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (808 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
GRM5Glutamate metabotropic receptor 5. (885 aa)
GNG13G protein subunit gamma 13. (67 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2754 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (646 aa)
GLSGlutaminase. (602 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (890 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2499 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (940 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1120 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
GNB4G protein subunit beta 4. (341 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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