STRINGSTRING
PRKCB PRKCB RAB3B RAB3B GPR119 GPR119 KCNU1 KCNU1 ATF6B ATF6B KCNJ11 KCNJ11 GCK GCK ADCYAP1 ADCYAP1 CCKAR CCKAR INS INS H0XTN8_OTOGA H0XTN8_OTOGA ITPR3 ITPR3 GNAS GNAS H0XPH7_OTOGA H0XPH7_OTOGA CAMK2B CAMK2B ATF4 ATF4 ATP1B4 ATP1B4 STX1A STX1A LOC100966244 LOC100966244 CAMK2G CAMK2G RYR2 RYR2 KCNMB1 KCNMB1 CREB3L4 CREB3L4 ADCY6 ADCY6 PDX1 PDX1 KCNMB2 KCNMB2 CCK CCK ADCY5 ADCY5 RAB3C RAB3C RIMS2 RIMS2 RAPGEF4 RAPGEF4 PRKCA PRKCA FAP FAP GCG GCG KCNN1 KCNN1 PRKACA PRKACA ATF2 ATF2 ATP1A2 ATP1A2 ADCY7 ADCY7 CACNA1C CACNA1C CREB3L2 CREB3L2 TNIK TNIK SLC2A2 SLC2A2 CREB5 CREB5 CAMK2D CAMK2D RAB3A RAB3A CACNA1F CACNA1F GIP GIP ATP1B1 ATP1B1 PLCB2 PLCB2 ATP1B2 ATP1B2 KCNN2 KCNN2 CREB3L1 CREB3L1 ATP1B3 ATP1B3 KCNMB4 KCNMB4 PRKCG PRKCG KCNMA1 KCNMA1 PLCB4 PLCB4 PLCB3 PLCB3 CREB1 CREB1 KCNN4 KCNN4 PLCB1 PLCB1 KCNMB3 KCNMB3 ABCC8 ABCC8 ADCY4 ADCY4 PRKACB PRKACB KCNN3 KCNN3 SNAP25 SNAP25 H0WQJ9_OTOGA H0WQJ9_OTOGA ADCY1 ADCY1 ARSI ARSI CAMK2A CAMK2A PCLO PCLO GLP1R GLP1R ADCY9 ADCY9 SLC2A1 SLC2A1 H0WJR3_OTOGA H0WJR3_OTOGA ADCYAP1R1 ADCYAP1R1 CACNA1S CACNA1S CREB3L3 CREB3L3 ADCY8 ADCY8 ADCY2 ADCY2 TRPM4 TRPM4 ADCY3 ADCY3 PTRHD1 PTRHD1 ATP1A1 ATP1A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
RAB3BRAB3B, member RAS oncogene family. (227 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1156 aa)
ATF6BActivating transcription factor 6 beta. (705 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
GCKPhosphotransferase. (466 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
H0XTN8_OTOGAUncharacterized protein. (209 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2728 aa)
GNASGNAS complex locus. (1146 aa)
H0XPH7_OTOGAFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (664 aa)
ATF4Activating transcription factor 4. (352 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (358 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (326 aa)
LOC100966244Uncharacterized protein. (260 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (651 aa)
RYR2Ryanodine receptor 2. (4867 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (368 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
CCKCholecystokinin. (115 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1381 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (847 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (691 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GCGGlucagon. (180 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (504 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (486 aa)
TNIKTRAF2 and NCK interacting kinase. (1325 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (518 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (507 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (502 aa)
RAB3ARAB3A, member RAS oncogene family. (227 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
GIPGastric inhibitory polypeptide. (150 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (703 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (243 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (154 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1076 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (258 aa)
ABCC8ATP binding cassette subfamily C member 8. (1594 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (713 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
H0WQJ9_OTOGASodium/potassium-transporting ATPase subunit alpha. (1022 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ARSIArylsulfatase family member I. (572 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (490 aa)
PCLOPiccolo presynaptic cytomatrix protein. (4040 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (503 aa)
H0WJR3_OTOGAV-SNARE coiled-coil homology domain-containing protein. (115 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (470 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1874 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (463 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1120 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1101 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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