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| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (243 aa) |
| | STAT1 | Signal transducer and activator of transcription. (762 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (468 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (859 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1093 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (685 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) |
| | E2F3 | E2F transcription factor 3. (463 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1143 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (470 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | IRF7 | Interferon regulatory factor 7. (495 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (729 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta. (387 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa) |
| | CLDN34 | Uncharacterized protein. (216 aa) |
| | FAS | Fas cell surface death receptor. (324 aa) |
| | H0WU85_OTOGA | Uncharacterized protein. (451 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (709 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | RB1 | RB transcriptional corepressor 1. (929 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (663 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (535 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | ERAS | ES cell expressed Ras. (229 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1653 aa) |
| | YWHAB | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1178 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (323 aa) |
| | PSME3 | Proteasome activator subunit 3. (254 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (590 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (740 aa) |
| | IFIT5 | Interferon induced protein with tetratricopeptide repeats 5. (481 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (409 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (202 aa) |
| | DDX58 | DExD/H-box helicase 58. (926 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa) |
| | RXRA | Retinoid X receptor alpha. (467 aa) |
| | TYK2 | Tyrosine-protein kinase. (1184 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (486 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | IRF3 | Interferon regulatory factor 3. (428 aa) |
| | E2F2 | E2F transcription factor 2. (438 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (465 aa) |
| | CSDE1 | Cold shock domain containing E1. (813 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (602 aa) |
| | H0X7G6_OTOGA | Uncharacterized protein. (523 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (964 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (420 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (591 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (429 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (651 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (249 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (243 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (549 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (380 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (471 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (584 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | LDLR | Low density lipoprotein receptor. (869 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | H0XI59_OTOGA | 14_3_3 domain-containing protein. (62 aa) |
| | H0XJE1_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XJN6_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XJR3_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (443 aa) |
| | H0XKQ8_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | H0XLK2_OTOGA | Uncharacterized protein. (247 aa) |
| | LOC100952744 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC100946237 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) |
| | H0XN39_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (708 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (747 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (224 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (362 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (420 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (336 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (286 aa) |
| | E2F1 | E2F transcription factor 1. (385 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (Predicted); Belongs to the 14-3-3 family. (246 aa) |
| | PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (134 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | IFIT1 | Interferon induced protein with tetratricopeptide repeats 1. (479 aa) |
| | IFIT2 | Interferon induced protein with tetratricopeptide repeats 2. (469 aa) |
| | H0Y0D2_OTOGA | Uncharacterized protein. (194 aa) |
| | H0XZI5_OTOGA | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | H0WHZ3_OTOGA | Uncharacterized protein. (731 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (631 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (525 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (193 aa) |
| | H0XWQ9_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XWX2_OTOGA | Uncharacterized protein. (72 aa) |
| | LOC100953470 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) |
| | IRF9 | Interferon regulatory factor 9. (431 aa) |
| | TRADD | TNFRSF1A associated via death domain. (309 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | H0XYF5_OTOGA | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (165 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (689 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | STAT2 | Signal transducer and activator of transcription. (816 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa) |
| | IFIT3 | Interferon induced protein with tetratricopeptide repeats 3. (485 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (308 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (552 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | H0WLJ8_OTOGA | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (201 aa) |
