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| | ENSOGAP00000022545 | annotation not available (643 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (525 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (631 aa) |
| | H0WHZ3_OTOGA | Uncharacterized protein. (731 aa) |
| | STAT5A | Signal transducer and activator of transcription. (793 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | STAT2 | Signal transducer and activator of transcription. (816 aa) |
| | BCL2 | BCL2 apoptosis regulator. (238 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (552 aa) |
| | H0WLB6_OTOGA | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | H0WLJ8_OTOGA | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (201 aa) |
| | RAB9A | RAB9A, member RAS oncogene family. (201 aa) |
| | STAT1 | Signal transducer and activator of transcription. (762 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | LIMCH1 | LIM and calponin homology domains 1. (927 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (859 aa) |
| | H0WPC6_OTOGA | Uncharacterized protein. (211 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1093 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (685 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | IRF7 | Interferon regulatory factor 7. (495 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (266 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (729 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (273 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1157 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (559 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta. (387 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (642 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FAS | Fas cell surface death receptor. (324 aa) |
| | H0WU85_OTOGA | Uncharacterized protein. (451 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (709 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | MSN | Moesin. (573 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (535 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (461 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | NFKBIB | NFKB inhibitor beta. (355 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1653 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa) |
| | H0WZM7_OTOGA | C-type lectin domain-containing protein. (372 aa) |
| | H0WZN3_OTOGA | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (366 aa) |
| | CD3D | CD3d molecule. (172 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (590 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (409 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) |
| | DDX58 | DExD/H-box helicase 58. (926 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | TYK2 | Tyrosine-protein kinase. (1184 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (783 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | IRF3 | Interferon regulatory factor 3. (428 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | CD28 | CD28 molecule. (218 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1024 aa) |
| | H0X7G6_OTOGA | Uncharacterized protein. (523 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (964 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (217 aa) |
| | H0X995_OTOGA | Ig-like domain-containing protein. (132 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (429 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | RACK1 | WD_REPEATS_REGION domain-containing protein. (317 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (549 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (380 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (471 aa) |
| | RAB9B | RAB9B, member RAS oncogene family. (201 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (710 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (280 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (584 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (338 aa) |
| | LOC100961427 | Uncharacterized protein. (1127 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1048 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | STAT5B | Signal transducer and activator of transcription. (788 aa) |
| | TRAC | T cell receptor alpha constant. (157 aa) |
| | H0XJE1_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XJN6_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XJR3_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | H0XKQ8_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | H0XL50_OTOGA | Ig-like domain-containing protein. (135 aa) |
| | LOC100952744 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC100946237 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | H0XN39_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (747 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | H0XNR5_OTOGA | Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (420 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BBC3 | Uncharacterized protein. (193 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | H0XSZ0_OTOGA | WD_REPEATS_REGION domain-containing protein. (215 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (698 aa) |
| | H0XTA8_OTOGA | Ig-like domain-containing protein. (135 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (321 aa) |
| | H0XUL8_OTOGA | C-type lectin domain-containing protein. (242 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (252 aa) |
| | H0XWQ9_OTOGA | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | H0XWX2_OTOGA | Uncharacterized protein. (72 aa) |
| | IRF9 | Interferon regulatory factor 9. (431 aa) |
| | HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (635 aa) |
| | TRADD | TNFRSF1A associated via death domain. (309 aa) |
| | H0XYD5_OTOGA | Uncharacterized protein. (413 aa) |
| | H0Y000_OTOGA | Uncharacterized protein; Belongs to the heat shock protein 70 family. (538 aa) |
| | H0Y0D2_OTOGA | Uncharacterized protein. (194 aa) |
| | H0Y0E0_OTOGA | Ig-like domain-containing protein. (116 aa) |
| | H0Y116_OTOGA | Fibronectin type-III domain-containing protein. (376 aa) |
| | TRAV18 | T cell receptor alpha variable 18. (120 aa) |
| | PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (134 aa) |
| | LY6G5B | Lymphocyte antigen 6 family member G5B. (195 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa) |
