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| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (442 aa) |
| | gyrB | DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (772 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | Cla_0022 | Conserved hypothetical protein; Pfam match to PF04055.12 Radical_SAM. (336 aa) |
| | nrdA | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (603 aa) |
| | Cla_0033 | Conserved hypothetical protein, putative MoxR/RavA-like ATPase; Pfam matches to PF07728.5 AAA_5, and to PF03382.5 DUF285. (560 aa) |
| | lig | Pfam match to PF01068.12 DNA_ligase_A_M. (312 aa) |
| | znuC | Cation ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (249 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (123 aa) |
| | nrdD | Anaerobic ribonucleoside triphosphate reductase; Pfam match to PF03477.7 ATP-cone. (759 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Pfam matches to PF00586.15 AIRS, and to PF02769.13 AIRS_C. (329 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (193 aa) |
| | Cla_0056 | Conserved hypothetical ATP-binding protein. (353 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (299 aa) |
| | hisIE | phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502.9 PRA-CH, and to PF01503.8 PRA-PH; In the N-terminal section; belongs to the PRA-CH family. (208 aa) |
| | Cla_0108 | Conserved hypothetical protein. (193 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (427 aa) |
| | iamA | Putative ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (240 aa) |
| | recA | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (344 aa) |
| | obg | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (347 aa) |
| | parA | Chromosome partitioning protein ParA; Pfam match to PF01656.14 CbiA. (260 aa) |
| | atpA | ATP synthase F1 sector, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (501 aa) |
| | atpG | ATP synthase F1 sector, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpD | ATP synthase F1 sector, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (484 aa) |
| | atpC | ATP synthase F1 sector, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (130 aa) |
| | accD | acetyl-CoA carboxylase, carboxyltransferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (292 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (877 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam match to PF01288.11 HPPK. (157 aa) |
| | flhF | Flagellar biosynthesis (GTP-binding) protein FlhF; Pfam match to PF00448.13 SRP54. (461 aa) |
| | flhG | Conserved hypothetical protein, ATPase, ParA family; Pfam match to PF01656.14 CbiA. (287 aa) |
| | trmU | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (338 aa) |
| | Cla_0244 | Conserved hypothetical protein, putative two-component response regulator; Pfam match to PF00072.15 Response_reg. (291 aa) |
| | mrp | ATP/GTP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (367 aa) |
| | pgi | Glucose-6-phosphate isomerase; Pfam match to PF00342.10 PGI. (407 aa) |
| | Cla_0254 | ABC transporter, ATP-binding protein; Pfam matches to PF00005.18 ABC_tran, and to PF00005.18 ABC_tran. (524 aa) |
| | tilS | tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (318 aa) |
| | murD | Pfam match to PF08245.3 Mur_ligase_M; Belongs to the MurCDEF family. (399 aa) |
| | feoB | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (674 aa) |
| | accA | acetyl-CoA carboxylase, carboxyltransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | kpsT | Capsular polysaccharide ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (223 aa) |
| | kpsF | Arabinose-5-phosphate isomerase; Pfam matches to PF01380.13 SIS, and to PF00571.19 CBS; Belongs to the SIS family. GutQ/KpsF subfamily. (318 aa) |
| | Cla_0314 | Conserved hypothetical protein. (774 aa) |
| | cysC | Pfam match to PF01583.11 APS_kinase. (168 aa) |
| | Cla_0336 | Conserved hypothetical protein, predicted ATP/GTP-binding protein; Pfam match to PF00350.14 Dynamin_N. (741 aa) |
| | Cla_0337 | Conserved hypothetical protein, predicted ATP/GTP-binding protein. (605 aa) |
| | Cla_0339 | Conserved hypothetical protein, pyridoxamine 5'-phosphate oxidase family; Pfam match to PF01243.11 Pyridox_oxidase. (168 aa) |
| | hsdR | Type I restriction-modification system, R subunit; Pfam matches to PF04313.5 HSDR_N, and to PF04851.6 ResIII. (770 aa) |
| | selD | Selenide, water dikinase (possible start at 335663); Pfam match to PF02769.13 AIRS_C. (320 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (416 aa) |
| | pyrAa | Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.13 CPSase_sm_chain, and to PF00117.19 GATase; Belongs to the CarA family. (372 aa) |
| | addA | ATP-dependent DNA helicase, UvrD/REP family; Pfam match to PF00580.12 UvrD-helicase; Belongs to the helicase family. UvrD subfamily. (915 aa) |
| | ctsE | Putative type II protein secretion system E protein CtsE; Pfam match to PF00437.11 GSPII_E. (504 aa) |
| | thiL | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (273 aa) |
| | fldA | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (163 aa) |
| | pgk | Phosphoglycerate kinase; Pfam match to PF00162.10 PGK; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (181 aa) |
| | rsfS | Conserved hypothetical protein (DUF143 domain protein); Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (109 aa) |
| | glmS | Glucosamine fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (599 aa) |
| | tuf | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa) |
| | rpoB | DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1377 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (691 aa) |
| | Cla_0454 | Conserved hypothetical protein. (89 aa) |
| | Cla_0456 | Transmembrane transport protein, SbmA/BacA family; Pfam match to PF05992.3 SbmA_BacA. (326 aa) |
| | dnaX | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (510 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (434 aa) |
| | ccoI | Heavy metal translocating P-type ATPase; Pfam matches to PF00122.11 E1-E2_ATPase, and to PF00702.17 Hydrolase. (781 aa) |
| | waaE | D,D-heptose 1-phosphate adenosyltransferase/7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (457 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (186 aa) |
| | pyk | Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family. (483 aa) |
| | coaX | Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (207 aa) |
| | gatC | glu-tRNAGln amidotransferase, subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | lysS | lysyl-tRNA synthetase; Pfam matches to PF01336.16 tRNA_anti, and to PF00152.11 tRNA-synt_2; Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa) |
| | Cla_0490 | Conserved hypothetical protein (DUF1882 domain protein); Pfam match to PF08966.2 DUF1882. (181 aa) |
| | Cla_0491 | Conserved hypothetical protein; Pfam match to PF05036.4 SPOR. (268 aa) |
| | dnaJ | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] (373 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (511 aa) |
| | Cla_0503 | Conserved hypothetical protein. (479 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Pfam matches to PF02844.6 GARS_N, and to PF01071.10 GARS_A; Belongs to the GARS family. (416 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (863 aa) |
| | flgR | Sigma-54 dependent DNA-binding response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00158.17 Sigma54_activat. (429 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (411 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Pfam match to PF00579.16 tRNA-synt_1b; Belongs to the class-I aminoacyl-tRNA synthetase family. (319 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa) |
| | der | Conserved hypothetical protein, predicted GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (461 aa) |
| | Cla_0546 | DnaJ-like protein; Pfam match to PF00226.22 DnaJ. (256 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase, PurL subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (725 aa) |
| | trmE | tRNA modification GTPase, TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (442 aa) |
| | Cla_0571 | ABC transporter, ATP-binding protein; Pfam matches to PF00005.18 ABC_tran, and to PF00005.18 ABC_tran. (645 aa) |
| | pycA | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (480 aa) |
| | Cla_0590 | DnaJ domain protein; Pfam match to PF00226.22 DnaJ. (268 aa) |
| | Cla_0594 | Conserved hypothetical protein (DUF234 domain protein); Pfam match to PF03008.5 DUF234. (283 aa) |
| | Cla_0598 | Amino acid ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (242 aa) |
| | glyS | glycyl-tRNA synthetase, beta subunit; Pfam match to PF02092.8 tRNA_synt_2f. (664 aa) |
| | ftsE | Cell division ATP-binding protein FtsE; Pfam match to PF00005.18 ABC_tran. (219 aa) |
| | ftsX | Cell division protein FtsX. (268 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (400 aa) |
| | msbA | ABC transporter, ATP-binding protein/permease MsbA, putative; Pfam matches to PF00664.14 ABC_membrane, and to PF00005.18 ABC_tran. (587 aa) |
| | cysS | cysteinyl-tRNA synthetase; Pfam matches to PF01406.10 tRNA-synt_1e, and to PF09190.2 DALR_2; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa) |
| | ruvA | Holliday junction DNA helicase, DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (183 aa) |
| | ddlA | D-alanine--D-alanine ligase; Cell wall formation. (346 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Pfam match to PF08245.3 Mur_ligase_M. (466 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | metN | ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (318 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (870 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (583 aa) |
| | nadK | Conserved hypothetical protein, putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (504 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (279 aa) |
| | Cla_0658 | OstA family protein; Pfam match to PF03968.5 OstA. (152 aa) |
| | engB | Conserved hypothetical protein, predicted ATP/GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (199 aa) |
| | lysC | Aspartate kinase; Pfam matches to PF00696.19 AA_kinase, and to PF01842.16 ACT; Belongs to the aspartokinase family. (400 aa) |
| | ribF | Riboflavin kinase/FAD synthase; Pfam matches to PF06574.3 FAD_syn, and to PF01687.8 Flavokinase; Belongs to the ribF family. (280 aa) |
| | ychF | Conserved hypothetical protein, predicted GTP-binding protein (DUF933 domain protein); ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) |
| | papQ | Conserved hypothetical protein, ABC transporter, His/Glu/Gln/Arg/opine family (ATP-binding protein); Pfam match to PF00005.18 ABC_tran. (245 aa) |
| | ftsH1 | Cell division protein FtsH; Pfam match to PF00004.20 AAA; Belongs to the AAA ATPase family. (532 aa) |
| | mog | Molybdenum cofactor biosynthesis protein; Pfam match to PF00994.15 MoCF_biosynth. (175 aa) |
| | htpG | Heat shock protein HtpG, chaperone Hsp90; Molecular chaperone. Has ATPase activity. (609 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, PurQ subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (216 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (78 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam match to PF01259.9 SAICAR_synt; Belongs to the SAICAR synthetase family. (237 aa) |
| | clpB | Protein disaggregating chaperone ClpB; Pfam matches to PF02861.11 Clp_N, and to PF00004.20 AAA; Belongs to the ClpA/ClpB family. (857 aa) |
| | gltX1 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (431 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B; Pfam match to PF03205.5 MobB. (159 aa) |
| | metS | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (629 aa) |
| | Cla_0725 | Conserved hypothetical protein. (313 aa) |
| | queC | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (221 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (194 aa) |
| | hisS | histidyl-tRNA synthetase; Pfam match to PF00587.16 tRNA-synt_2b. (408 aa) |
| | Cla_0751 | ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (241 aa) |
| | argG | Argininosuccinate synthetase; Pfam match to PF00764.10 Arginosuc_synth; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (439 aa) |
| | era | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (290 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (565 aa) |
| | rep | ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase. (675 aa) |
| | pstB | Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (246 aa) |
| | ftsK | DNA segregation ATPase FtsK/SpoIIIE; Contains possible alternative start; Pfam matches to PF01580.9 FtsK_SpoIIIE, and to PF09397.1 Ftsk_gamma; Belongs to the FtsK/SpoIIIE/SftA family. (924 aa) |
| | Cla_0877 | Conserved hypothetical protein, putative ATPase, AAA family; Pfam match to PF00004.20 AAA. (640 aa) |
| | mcrB | Conserved hypothetical protein, putative ATPase, AAA family; Pfam match to PF07728.5 AAA_5. (638 aa) |
| | Cla_0883 | Conserved hypothetical protein; Pfam matches to PF07656.2 KWG, and to PF07656.2 KWG. (181 aa) |
| | Cla_0887 | Conserved hypothetical protein; Pfam match to PF07656.2 KWG. (515 aa) |
| | nadE | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (246 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (312 aa) |
| | macB | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (643 aa) |
| | aas | Pfam matches to PF07690.7 MFS_1, and to PF01553.12 Acyltransferase. (1170 aa) |
| | dnaK | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. (622 aa) |
| | lon | DNA-binding, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (792 aa) |
| | dfp | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (385 aa) |
| | ffh | Signal recognition particle protein; Pfam matches to PF02881.10 SRP54_N, and to PF00448.13 SRP54. (445 aa) |
| | glyQ | glycyl-tRNA synthetase, alpha chain; Pfam match to PF02091.6 tRNA-synt_2e. (286 aa) |
| | glnA | Glutamine synthetase; Pfam matches to PF03951.10 Gln-synt_N, and to PF00120.15 Gln-synt_C; Belongs to the glutamine synthetase family. (476 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (697 aa) |
| | groEL | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa) |
| | groES | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (86 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (979 aa) |
| | folC | Folylpolyglutamate synthase/dihydrofolate synthase; Pfam match to PF08245.3 Mur_ligase_M. (389 aa) |
| | leuS | leucyl-tRNA synthetase; Pfam match to PF00133.13 tRNA-synt_1; Belongs to the class-I aminoacyl-tRNA synthetase family. (809 aa) |
| | metK | S-adenosylmethionine synthetase; Pfam matches to PF00438.11 S-AdoMet_synt_N, and to PF02772.7 S-AdoMet_synt_M; Belongs to the AdoMet synthase family. (397 aa) |
| | uvrD | ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase. (687 aa) |
| | ispE | Pfam match to PF00288.17 GHMP_kinases_N; Belongs to the GHMP kinase family. IspE subfamily. (251 aa) |
| | clpA | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. (709 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (845 aa) |
| | yedZ | Conserved hypothetical integral membrane protein; Pfam match to PF01794.10 Ferric_reduct. (186 aa) |
| | copA | Cation-transporting ATPase, P-type; Pfam matches to PF00403.17 HMA, and to PF00122.11 E1-E2_ATPase. (706 aa) |
| | argS | arginyl-tRNA synthetase; Pfam matches to PF03485.7 Arg_tRNA_synt_N, and to PF00750.10 tRNA-synt_1d. (531 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa) |
| | Cla_1092 | ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (211 aa) |
| | livG | Branched-chain amino acid ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (256 aa) |
| | livF | Branched-chain amino acid ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (231 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (596 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (260 aa) |
| | ribA | GTP cyclohydrolase II; Pfam match to PF00925.11 GTP_cyclohydro2. (186 aa) |
| | gyrA | DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (858 aa) |
| | mutS | Mismatch repair ATPase MutS, MutS2 family; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (731 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (430 aa) |
| | gatA | glu-tRNAGln amidotransferase, subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (454 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (921 aa) |
| | Cla_1165 | ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (218 aa) |
| | ftsA | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (459 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (368 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (614 aa) |
| | uvrB | Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (657 aa) |
| | pheT | phenylalanyl-tRNA synthetase, beta subunit; Pfam matches to PF01588.11 tRNA_bind, and to PF03484.6 B5; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (776 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; Pfam matches to PF02912.9 Phe_tRNA-synt_N, and to PF01409.11 tRNA-synt_2d; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (330 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (524 aa) |
| | gatB | glu-tRNAGln amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (472 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (446 aa) |
| | ftsY | Signal recognition particle-docking GTPase FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (288 aa) |
| | Cla_1213 | Conserved hypothetical protein, 5-formyltetrahydrofolate cyclo-ligase family; Pfam match to PF01812.11 5-FTHF_cyc-lig; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (209 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (461 aa) |
| | pglK | ABC transporter, ATP-binding protein/permease, glycan transport; Pfam match to PF00005.18 ABC_tran. (564 aa) |
| | ftsH2 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (640 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa) |
| | ruvB | Holliday junction DNA helicase, ATPase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | modC | Molybdenum ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (289 aa) |
| | selB | Selenocysteine-specific elongation factor; Pfam matches to PF00009.18 GTP_EFTU, and to PF03144.16 GTP_EFTU_D2. (601 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa) |
| | pseA | Pseudaminic acid biosynthesis protein PseA. (378 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | uvrA | Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (190 aa) |
| | carB | Carbamoylphosphate synthase, large subunit; Pfam matches to PF00289.13 CPSase_L_chain, and to PF02786.8 CPSase_L_D2; Belongs to the CarB family. (1087 aa) |
| | mreB | Rod shape-determining protein MreB; Pfam match to PF06723.4 MreB_Mbl. (345 aa) |
| | clpX | ATP-dependent ClpXP protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (411 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (291 aa) |
| | dppF | Peptide ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (222 aa) |
| | dppD | Peptide ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (257 aa) |
| | Cla_1473 | Conserved hypothetical protein, possible sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (448 aa) |
| | Cla_1476 | Mg chelatase-related protein; Pfam match to PF01078.12 Mg_chelatase. (502 aa) |
| | folE | Pfam match to PF01227.13 GTP_cyclohydroI. (190 aa) |
| | fliI | Flagellum-specific ATP synthase FliI; Pfam match to PF00006.16 ATP-synt_ab. (436 aa) |
| | Cla_1498 | Conserved hypothetical protein. (327 aa) |
| | typA | GTP-binding protein TypA; Pfam matches to PF00009.18 GTP_EFTU, and to PF03144.16 GTP_EFTU_D2. (602 aa) |
| | Cla_1524 | ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran; Belongs to the ABC transporter superfamily. (326 aa) |
| | Cla_1528 | ABC transporter, ATP-binding protein; Pfam match to PF00005.18 ABC_tran. (542 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (192 aa) |
| | Cla_1549 | ATPase, AAA family protein; Pfam match to PF00004.20 AAA. (570 aa) |
| | rarA | ATPase, AAA family protein; Pfam match to PF00004.20 AAA. (396 aa) |
