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| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (249 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (634 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Pfam match to PF00459.16 Inositol_P. (231 aa) |
| | accD | acetyl-CoA carboxylase, carboxyltransferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (292 aa) |
| | sat | Sulfate adenylyltransferase, putative. (386 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (387 aa) |
| | pgi | Glucose-6-phosphate isomerase; Pfam match to PF00342.10 PGI. (407 aa) |
| | Cla_0256 | Phosphohexosemutase; Pfam matches to PF02878.7 PGM_PMM_I, and to PF02879.7 PGM_PMM_II. (455 aa) |
| | pgm | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (492 aa) |
| | accA | acetyl-CoA carboxylase, carboxyltransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | frdC | Fumarate reductase, cytochrome b subunit; Pfam match to PF02967.5 Fum_red_TM. (259 aa) |
| | frdA | Fumarate reductase, flavoprotein subunit; Pfam matches to PF00890.15 FAD_binding_2, and to PF02910.11 Succ_DH_flav_C. (668 aa) |
| | frdB | Fumarate reductase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (241 aa) |
| | Cla_0343 | NADP-dependent alcohol dehydrogenase; Pfam matches to PF08240.3 ADH_N, and to PF00107.17 ADH_zinc_N. (360 aa) |
| | fdhC | Formate dehydrogenase, cytochrome b subunit. (309 aa) |
| | fdhA | Formate dehydrogenase, alpha subunit (selenocysteine-containing); Pfam matches to PF04879.7 Molybdop_Fe4S4, and to PF00384.13 Molybdopterin; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (940 aa) |
| | fdhB | Formate dehydrogenase, beta (iron-sulfur) subunit; Pfam match to PF00037.18 Fer4. (189 aa) |
| | por | Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR. (1184 aa) |
| | Cla_0403 | Conserved hypothetical protein. (234 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (226 aa) |
| | pgk | Phosphoglycerate kinase; Pfam match to PF00162.10 PGK; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase; Pfam matches to PF00044.15 Gp_dh_N, and to PF02800.11 Gp_dh_C; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | bisC | Biotin sulfoxide reductase; Pfam matches to PF00384.13 Molybdopterin, and to PF01568.12 Molydop_binding; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (799 aa) |
| | pyk | Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family. (483 aa) |
| | mqo | Malate:quinone oxidoreductase; Pfam match to PF01266.15 DAO. (448 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; Pfam match to PF00202.12 Aminotran_3. (425 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | pycA | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (480 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | pta | Phosphate acetyltransferase; Pfam match to PF01515.10 PTA_PTB. (489 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | lysC | Aspartate kinase; Pfam matches to PF00696.19 AA_kinase, and to PF01842.16 ACT; Belongs to the aspartokinase family. (400 aa) |
| | rpiB | Ribose 5-phosphate isomerase B; Pfam match to PF02502.9 LacAB_rpiB. (145 aa) |
| | fbp | Fructose-1,6-biphosphatase; Pfam match to PF00316.11 FBPase. (282 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Pfam match to PF02441.10 Flavoprotein. (193 aa) |
| | cysE | Serine O-acetyltransferase. (201 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (308 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (435 aa) |
| | oorC | 2-oxoglutarate:acceptor oxidoreductase, OorC subunit; Pfam match to PF01558.9 POR. (185 aa) |
| | oorB | 2-oxoglutarate:acceptor oxidoreductase, OorB subunit; Pfam match to PF02775.12 TPP_enzyme_C. (281 aa) |
| | oorA | 2-oxoglutarate:acceptor oxidoreductase, OorA subunit; Pfam match to PF01855.10 POR_N. (374 aa) |
| | oorD | 2-oxoglutarate:acceptor oxidoreductase, OorD subunit; Pfam matches to PF00037.18 Fer4, and to PF00037.18 Fer4. (102 aa) |
| | mdh | Malate dehydrogenase; Pfam matches to PF00056.14 Ldh_1_N, and to PF02866.9 Ldh_1_C; Belongs to the LDH/MDH superfamily. (298 aa) |
| | thrC | Threonine synthase; Pfam match to PF00291.16 PALP. (469 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (354 aa) |
| | glnA | Glutamine synthetase; Pfam matches to PF03951.10 Gln-synt_N, and to PF00120.15 Gln-synt_C; Belongs to the glutamine synthetase family. (476 aa) |
| | napB | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (172 aa) |
| | napA | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (924 aa) |
| | nrfH | Cytochrome c nitrite reductase, small subunit NrfH. (164 aa) |
| | nrfA | Cytochrome c nitrite reductase, catalytic subunit NrfA; Pfam match to PF02335.6 Cytochrom_C552; Belongs to the cytochrome c-552 family. (605 aa) |
| | rpe | D-ribulose-5-phosphate 3-epimerase; Pfam match to PF00834.10 Ribul_P_3_epim; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa) |
| | hemD | Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (212 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Pfam match to PF00490.12 ALAD; Belongs to the ALAD family. (326 aa) |
| | Cla_1132 | Conserved hypothetical protein, putative iron-sulfur-cluster binding protein; Pfam matches to PF02754.7 CCG, and to PF02754.7 CCG. (422 aa) |
| | dapE | N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (366 aa) |
| | Cla_1158 | Hydrolase, carbon-nitrogen family. (263 aa) |
| | Cla_1176 | Conserved hypothetical protein. (192 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Pfam matches to PF00389.21 2-Hacid_dh, and to PF01842.16 ACT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (524 aa) |
| | pycB | Pyruvate carboxylase, subunit B; Pfam matches to PF00682.10 HMGL-like, and to PF00364.13 Biotin_lipoyl. (592 aa) |
| | glcD | Glycolate oxidase; Pfam matches to PF01565.14 FAD_binding_4, and to PF02913.10 FAD-oxidase_C. (460 aa) |
| | cysK | Cysteine synthase A; Pfam match to PF00291.16 PALP; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa) |
| | gdhA | Glutamate dehydrogenase; Pfam matches to PF02812.9 ELFV_dehydrog_N, and to PF00208.12 ELFV_dehydrog; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (455 aa) |
| | mez | Malate oxidoreductase; Pfam matches to PF00390.10 malic, and to PF03949.6 Malic_M. (411 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (149 aa) |
| | serC | Phosphohydroxythreonine transaminase/phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (358 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (401 aa) |
| | tal | Transaldolase; Pfam match to PF00923.10 Transaldolase. (323 aa) |
| | serB | 3-phosphoserine phosphatase; Pfam match to PF00702.17 Hydrolase. (208 aa) |
| | Cla_1403 | 4-oxalocrotonate tautomerase family protein; Pfam match to PF01361.12 Tautomerase; Belongs to the 4-oxalocrotonate tautomerase family. (68 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (242 aa) |
| | hom | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. (417 aa) |
| | torA | Trimethylamine N-oxide reductase, catalytic subunit; Pfam matches to PF00384.13 Molybdopterin, and to PF01568.12 Molydop_binding; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (839 aa) |
| | HprA | 2-hydroxyacid dehydrogenase family protein; Pfam match to PF00389.21 2-Hacid_dh. (310 aa) |
