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jk1073 jk1073 hemG hemG hemE hemE cobA cobA ccsA ccsA ccsB ccsB ccdA ccdA ccsX ccsX jk1894 jk1894 hemL hemL ctpA2 ctpA2 jk1897 jk1897 jk1898 jk1898 hemB hemB hemD hemD hemC hemC hemA hemA hemH hemH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
jk1073Conserved hypothetical protein. (238 aa)
hemGProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (481 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (385 aa)
cobAuroporphyrinogen-III methylase. (243 aa)
ccsACytochrome c biogenesis protein. (370 aa)
ccsBMembrane protein required for cytochrome c biosynthesis. (552 aa)
ccdACytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). (265 aa)
ccsXThiol-disulfide isomerase/thioredoxin. (202 aa)
jk1894Probable phosphoglycerate mutase gpmB (EC 5.4.2.1) (Phosphoglyceromutase) (PGAM). (201 aa)
hemLGlutamate-1-semialdehyde 21-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT). (443 aa)
ctpA2Putative cation-transporting P-type ATPase. (923 aa)
jk1897Putative membrane protein. (181 aa)
jk1898Putative membrane protein. (290 aa)
hemBPorphobilinogen synthase; Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH); Belongs to the ALAD family. (334 aa)
hemDuroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Porphyrin biosynthesis protein HEMD [Includes: Uroporphyrin-III C- methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing])].,May catalyze sequential reactions to synthesize UroIII from hydroxymethylbilane (HMB) and then precorrin-2 which are intermediate compounds in both vitamin B12 and siroheme biosyntheses. (628 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (367 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (497 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (424 aa)
Your Current Organism:
Corynebacterium jeikeium
NCBI taxonomy Id: 306537
Other names: C. jeikeium K411, Corynebacterium jeikeium K411, Corynebacterium jeikeium str. K411, Corynebacterium jeikeium strain K411
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