| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dhbE | menF | jk1820 | jk1285 | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | Isochorismate synthase dhbC (EC 5.4.4.2) (Isochorismate mutase). | 0.956 |
| dhbE | pabB | jk1820 | jk0031 | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | Para-aminobenzoate synthase (EC 6.3.5.8) (P-aminobenzoic acid synthase) (PABA synthase).,Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. | 0.732 |
| dhbE | trpE | jk1820 | jk0795 | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.897 |
| menF | dhbE | jk1285 | jk1820 | Isochorismate synthase dhbC (EC 5.4.4.2) (Isochorismate mutase). | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | 0.956 |
| menF | trpE | jk1285 | jk0795 | Isochorismate synthase dhbC (EC 5.4.4.2) (Isochorismate mutase). | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.861 |
| pabB | dhbE | jk0031 | jk1820 | Para-aminobenzoate synthase (EC 6.3.5.8) (P-aminobenzoic acid synthase) (PABA synthase).,Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | 0.732 |
| pabB | trpE | jk0031 | jk0795 | Para-aminobenzoate synthase (EC 6.3.5.8) (P-aminobenzoic acid synthase) (PABA synthase).,Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.850 |
| trpE | dhbE | jk0795 | jk1820 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 23-dihydroxybenzoate-AMP ligase (EC 6.3.2.-) (Dihydroxybenzoic acid- activating enzyme).,Activation of the carboxylate group of 23-dihydroxy- benzoate (DHB) via ATP-dependent PPi exchange reactions to the acyladenylate. | 0.897 |
| trpE | menF | jk0795 | jk1285 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | Isochorismate synthase dhbC (EC 5.4.4.2) (Isochorismate mutase). | 0.861 |
| trpE | pabB | jk0795 | jk0031 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | Para-aminobenzoate synthase (EC 6.3.5.8) (P-aminobenzoic acid synthase) (PABA synthase).,Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. | 0.850 |