(15 nodes) Endoplasmic reticulum unfolded protein response network (Volvox carteri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D8UD78_VOLCA	Protein kinase domain-containing protein. (870 aa)
	D8UJK3_VOLCA	PRKCSH domain-containing protein. (257 aa)
	D8UIG7_VOLCA	Uncharacterized protein. (181 aa)
	D8UI78_VOLCA	Uncharacterized protein. (499 aa)
	D8UHN4_VOLCA	Rhomboid domain-containing protein. (373 aa)
	D8UHE6_VOLCA	Uncharacterized protein. (1304 aa)
	D8UA83_VOLCA	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (213 aa)
	D8U9Q6_VOLCA	Uncharacterized protein. (328 aa)
	D8U645_VOLCA	Uncharacterized protein. (70 aa)
	D8U489_VOLCA	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (257 aa)
	D8U1L4_VOLCA	Uncharacterized protein. (476 aa)
	bip2	Luminal binding protein Bip2. (878 aa)
	bip1	Luminal binding protein Bip1; Belongs to the heat shock protein 70 family. (653 aa)
	D8TNE8_VOLCA	Ubiquitin-like domain-containing protein. (686 aa)
	D8TH51_VOLCA	Uncharacterized protein. (336 aa)

Your Current Organism:

Volvox carteri

NCBI taxonomy Id: 3068
Other names: V. carteri f. nagariensis, Volvox carteri f. nagariensis, Volvox carteri f. nagariensis M.O.P.Iyengar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D8TH51_VOLCA	D8U489_VOLCA	D8TH51	D8U489	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.540
D8TH51_VOLCA	D8UA83_VOLCA	D8TH51	D8UA83	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.540
D8TH51_VOLCA	D8UD78_VOLCA	D8TH51	D8UD78	Uncharacterized protein.	Protein kinase domain-containing protein.	0.779
D8TH51_VOLCA	D8UHE6_VOLCA	D8TH51	D8UHE6	Uncharacterized protein.	Uncharacterized protein.	0.779
D8TH51_VOLCA	D8UI78_VOLCA	D8TH51	D8UI78	Uncharacterized protein.	Uncharacterized protein.	0.540
D8TH51_VOLCA	D8UJK3_VOLCA	D8TH51	D8UJK3	Uncharacterized protein.	PRKCSH domain-containing protein.	0.598
D8U489_VOLCA	D8TH51_VOLCA	D8U489	D8TH51	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.540
D8U489_VOLCA	D8UA83_VOLCA	D8U489	D8UA83	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.910
D8U489_VOLCA	D8UJK3_VOLCA	D8U489	D8UJK3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	PRKCSH domain-containing protein.	0.921
D8U489_VOLCA	bip1	D8U489	D8TT41	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Luminal binding protein Bip1; Belongs to the heat shock protein 70 family.	0.540
D8U489_VOLCA	bip2	D8U489	D8TTA3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Luminal binding protein Bip2.	0.540
D8UA83_VOLCA	D8TH51_VOLCA	D8UA83	D8TH51	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.540
D8UA83_VOLCA	D8U489_VOLCA	D8UA83	D8U489	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.910
D8UA83_VOLCA	D8UJK3_VOLCA	D8UA83	D8UJK3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	PRKCSH domain-containing protein.	0.920
D8UA83_VOLCA	bip1	D8UA83	D8TT41	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Luminal binding protein Bip1; Belongs to the heat shock protein 70 family.	0.540
D8UA83_VOLCA	bip2	D8UA83	D8TTA3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Luminal binding protein Bip2.	0.540
D8UD78_VOLCA	D8TH51_VOLCA	D8UD78	D8TH51	Protein kinase domain-containing protein.	Uncharacterized protein.	0.779
D8UD78_VOLCA	bip1	D8UD78	D8TT41	Protein kinase domain-containing protein.	Luminal binding protein Bip1; Belongs to the heat shock protein 70 family.	0.779
D8UD78_VOLCA	bip2	D8UD78	D8TTA3	Protein kinase domain-containing protein.	Luminal binding protein Bip2.	0.779
D8UHE6_VOLCA	D8TH51_VOLCA	D8UHE6	D8TH51	Uncharacterized protein.	Uncharacterized protein.	0.779