(49 nodes) Disease network (Volvox carteri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D8U2M4_VOLCA	Uncharacterized protein. (1068 aa)
	D8U340_VOLCA	Protein kinase domain-containing protein. (743 aa)
	D8U3X1_VOLCA	Uncharacterized protein. (357 aa)
	D8U3X2_VOLCA	Pep3_Vps18 domain-containing protein. (642 aa)
	D8U3X3_VOLCA	Uncharacterized protein. (232 aa)
	D8U0Y5_VOLCA	TOG domain-containing protein. (1118 aa)
	D8U0Y1_VOLCA	LMWPc domain-containing protein. (219 aa)
	D8U0U0_VOLCA	MlaD domain-containing protein. (312 aa)
	D8TYH3_VOLCA	Vps39_2 domain-containing protein. (1432 aa)
	D8TW37_VOLCA	Pyr_redox_2 domain-containing protein. (3505 aa)
	D8TVA2_VOLCA	Uncharacterized protein. (201 aa)
	D8TV66_VOLCA	Uncharacterized protein. (313 aa)
	D8TV39_VOLCA	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (898 aa)
	D8TU76_VOLCA	Uncharacterized protein. (831 aa)
	D8TRV0_VOLCA	Uncharacterized protein. (3433 aa)
	D8TRD8_VOLCA	Uncharacterized protein. (555 aa)
	D8TRD7_VOLCA	TPR_REGION domain-containing protein. (115 aa)
	D8TR23_VOLCA	Uncharacterized protein. (789 aa)
	D8TQU6_VOLCA	CULT domain-containing protein. (594 aa)
	D8TQJ2_VOLCA	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (296 aa)
	D8TQ52_VOLCA	Uncharacterized protein. (478 aa)
	vps33	Uncharacterized protein vps33; Belongs to the STXBP/unc-18/SEC1 family. (703 aa)
	D8TN99_VOLCA	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (602 aa)
	D8TMP4_VOLCA	MlaD domain-containing protein. (327 aa)
	D8TL50_VOLCA	NTP_transf_2 domain-containing protein. (609 aa)
	D8TJQ3_VOLCA	Uncharacterized protein. (273 aa)
	D8TJ85_VOLCA	HTH La-type RNA-binding domain-containing protein. (134 aa)
	D8TJ84_VOLCA	Uncharacterized protein. (141 aa)
	D8TIG9_VOLCA	Protein kinase domain-containing protein. (609 aa)
	D8THQ9_VOLCA	Subunit of VPS-C complex. (1362 aa)
	D8UMW9_VOLCA	HTH arsR-type domain-containing protein. (287 aa)
	D8ULS5_VOLCA	Uncharacterized protein. (311 aa)
	D8UKG1_VOLCA	VPS11_C domain-containing protein. (186 aa)
	efg8	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (453 aa)
	amd1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (852 aa)
	D8UEJ1_VOLCA	Uncharacterized protein. (788 aa)
	D8UEA2_VOLCA	Thioredoxin reductase. (340 aa)
	D8UE64_VOLCA	Pyr_redox_2 domain-containing protein. (172 aa)
	D8UE14_VOLCA	Uncharacterized protein. (738 aa)
	D8UDV0_VOLCA	Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (674 aa)
	D8UDN2_VOLCA	Uncharacterized protein. (889 aa)
	dad1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (109 aa)
	D8UAL7_VOLCA	Uncharacterized protein. (767 aa)
	D8U919_VOLCA	NTP_transf_2 domain-containing protein. (1983 aa)
	D8U875_VOLCA	C3HC-type domain-containing protein. (680 aa)
	prxQ	Peroxiredoxin Q, thioredoxin dependent peroxidase chloroplast. (139 aa)
	mot42	Protein DETOXIFICATION; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (1427 aa)
	D8U471_VOLCA	Importin N-terminal domain-containing protein. (1029 aa)
	D8U453_VOLCA	Uncharacterized protein. (995 aa)

Your Current Organism:

Volvox carteri

NCBI taxonomy Id: 3068
Other names: V. carteri f. nagariensis, Volvox carteri f. nagariensis, Volvox carteri f. nagariensis M.O.P.Iyengar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D8THQ9_VOLCA	D8U3X1_VOLCA	D8THQ9	D8U3X1	Subunit of VPS-C complex.	Uncharacterized protein.	0.803
D8THQ9_VOLCA	D8U3X2_VOLCA	D8THQ9	D8U3X2	Subunit of VPS-C complex.	Pep3_Vps18 domain-containing protein.	0.803
D8THQ9_VOLCA	D8U3X3_VOLCA	D8THQ9	D8U3X3	Subunit of VPS-C complex.	Uncharacterized protein.	0.803
D8THQ9_VOLCA	D8U453_VOLCA	D8THQ9	D8U453	Subunit of VPS-C complex.	Uncharacterized protein.	0.941
D8THQ9_VOLCA	D8UDN2_VOLCA	D8THQ9	D8UDN2	Subunit of VPS-C complex.	Uncharacterized protein.	0.858
D8THQ9_VOLCA	D8UKG1_VOLCA	D8THQ9	D8UKG1	Subunit of VPS-C complex.	VPS11_C domain-containing protein.	0.858
D8THQ9_VOLCA	vps33	D8THQ9	D8TNT6	Subunit of VPS-C complex.	Uncharacterized protein vps33; Belongs to the STXBP/unc-18/SEC1 family.	0.936
D8TJ84_VOLCA	D8TJ85_VOLCA	D8TJ84	D8TJ85	Uncharacterized protein.	HTH La-type RNA-binding domain-containing protein.	0.431
D8TJ85_VOLCA	D8TJ84_VOLCA	D8TJ85	D8TJ84	HTH La-type RNA-binding domain-containing protein.	Uncharacterized protein.	0.431
D8TN99_VOLCA	D8TQ52_VOLCA	D8TN99	D8TQ52	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.402
D8TN99_VOLCA	D8TQJ2_VOLCA	D8TN99	D8TQJ2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.999
D8TN99_VOLCA	D8TR23_VOLCA	D8TN99	D8TR23	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.939
D8TN99_VOLCA	D8TV39_VOLCA	D8TN99	D8TV39	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.530
D8TN99_VOLCA	D8UAL7_VOLCA	D8TN99	D8UAL7	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.995
D8TN99_VOLCA	D8UE14_VOLCA	D8TN99	D8UE14	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.996
D8TN99_VOLCA	D8UEJ1_VOLCA	D8TN99	D8UEJ1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.417
D8TN99_VOLCA	amd1	D8TN99	D8UG85	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.469
D8TN99_VOLCA	dad1	D8TN99	D8UD77	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.998
D8TQ52_VOLCA	D8TN99_VOLCA	D8TQ52	D8TN99	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.402
D8TQ52_VOLCA	D8TQJ2_VOLCA	D8TQ52	D8TQJ2	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.515