(41 nodes) Proton-transporting two-sector ATPase complex network (Chaetomium globosum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	CHGG_10363	Uncharacterized protein. (348 aa)
	CHGG_10343	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (924 aa)
	CHGG_10255	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (519 aa)
	CHGG_10215	Uncharacterized protein. (219 aa)
	CHGG_10169	Uncharacterized protein. (395 aa)
	CHGG_09630	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
	CHGG_08506	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (104 aa)
	CHGG_08178	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (863 aa)
	CHGG_08127	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (347 aa)
	CHGG_07700	ATP-synt_ab domain-containing protein. (255 aa)
	CHGG_04880	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
	CHGG_04705	Uncharacterized protein. (299 aa)
	CHGG_04704	Uncharacterized protein. (75 aa)
	CHGG_04588	Vacuolar ATP synthase subunit D. (244 aa)
	CHGG_04501	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (202 aa)
	CHGG_04173	Uncharacterized protein. (72 aa)
	CHGG_06754	Uncharacterized protein. (50 aa)
	CHGG_06474	Uncharacterized protein. (230 aa)
	CHGG_06372	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (163 aa)
	CHGG_06274	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (173 aa)
	CHGG_05951	Uncharacterized protein. (431 aa)
	CHGG_05945	ATP synthase subunit 4, mitochondrial. (248 aa)
	CHGG_03673	Uncharacterized protein. (1250 aa)
	CHGG_02897	ATP-synt_DE_N domain-containing protein. (164 aa)
	CHGG_02797	V-ATPase_H_C domain-containing protein. (221 aa)
	CHGG_02796	Uncharacterized protein. (219 aa)
	CHGG_02654	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
	DED1	ATP-dependent RNA helicase DED1; ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. (688 aa)
	CHGG_02320	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (77 aa)
	CHGG_02318	Uncharacterized protein. (473 aa)
	CHGG_01812	Uncharacterized protein. (96 aa)
	CHGG_01691	Uncharacterized protein. (200 aa)
	CHGG_01616	ATP synthase subunit gamma. (298 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (114 aa)
	CHGG_01469	Inorganic pyrophosphatase. (290 aa)
	CHGG_01398	Uncharacterized protein. (126 aa)
	CHGG_01120	ATP-synt_ab_C domain-containing protein. (128 aa)
	CHGG_01119	Uncharacterized protein. (193 aa)
	CHGG_00935	Uncharacterized protein. (135 aa)
	CHGG_00734	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (200 aa)
	CHGG_00093	CFEM domain-containing protein. (412 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00093	CHGG_00734	Q2HI61	Q2HGC0	CFEM domain-containing protein.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.440
CHGG_00093	CHGG_00935	Q2HI61	Q2HFR9	CFEM domain-containing protein.	Uncharacterized protein.	0.514
CHGG_00093	CHGG_02654	Q2HI61	Q2HAV0	CFEM domain-containing protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.582
CHGG_00093	CHGG_04501	Q2HI61	Q2H145	CFEM domain-containing protein.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.670
CHGG_00093	CHGG_04588	Q2HI61	Q2H0V8	CFEM domain-containing protein.	Vacuolar ATP synthase subunit D.	0.487
CHGG_00093	CHGG_04880	Q2HI61	Q2H016	CFEM domain-containing protein.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.485
CHGG_00093	CHGG_06372	Q2HI61	Q2H4P3	CFEM domain-containing protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.464
CHGG_00093	CHGG_06474	Q2HI61	Q2H4E1	CFEM domain-containing protein.	Uncharacterized protein.	0.487
CHGG_00093	CHGG_07700	Q2HI61	Q2GWF4	CFEM domain-containing protein.	ATP-synt_ab domain-containing protein.	0.637
CHGG_00093	CHGG_08127	Q2HI61	Q2GV77	CFEM domain-containing protein.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.	0.676
CHGG_00093	CHGG_08178	Q2HI61	Q2GV26	CFEM domain-containing protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.727
CHGG_00093	CHGG_08506	Q2HI61	Q2GU48	CFEM domain-containing protein.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.480
CHGG_00093	CHGG_10169	Q2HI61	Q2GPD5	CFEM domain-containing protein.	Uncharacterized protein.	0.449
CHGG_00734	CHGG_00093	Q2HGC0	Q2HI61	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	CFEM domain-containing protein.	0.440
CHGG_00734	CHGG_00935	Q2HGC0	Q2HFR9	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.443
CHGG_00734	CHGG_01469	Q2HGC0	Q2HE85	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Inorganic pyrophosphatase.	0.805
CHGG_00734	CHGG_01616	Q2HGC0	Q2HDT8	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATP synthase subunit gamma.	0.458
CHGG_00734	CHGG_02318	Q2HGC0	Q2HBT6	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.917
CHGG_00734	CHGG_02320	Q2HGC0	Q2HBT4	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	0.803
CHGG_00734	CHGG_02654	Q2HGC0	Q2HAV0	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998