(39 nodes) RNA Polymerase II Promoter Escape network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10780	Uncharacterized protein. (361 aa)
	CHGG_10288	Helicase ATP-binding domain-containing protein. (732 aa)
	CHGG_10261	Uncharacterized protein. (652 aa)
	CHGG_10188	Uncharacterized protein. (408 aa)
	CHGG_09623	TFIID_20kDa domain-containing protein. (721 aa)
	CHGG_09156	TFIIE beta domain-containing protein. (406 aa)
	CHGG_08967	Uncharacterized protein. (84 aa)
	CHGG_08837	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (503 aa)
	CHGG_08424	Uncharacterized protein. (372 aa)
	CHGG_08285	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (202 aa)
	CHGG_08184	Uncharacterized protein. (165 aa)
	CHGG_08040	Uncharacterized protein. (499 aa)
	CHGG_07999	Uncharacterized protein. (224 aa)
	CHGG_07908	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	CHGG_07665	TAF domain-containing protein. (451 aa)
	CHGG_07476	CYCLIN domain-containing protein; Belongs to the cyclin family. (405 aa)
	CHGG_07339	Uncharacterized protein. (775 aa)
	CHGG_07212	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
	CHGG_05208	Uncharacterized protein. (439 aa)
	CHGG_04942	Uncharacterized protein. (373 aa)
	CHGG_04784	Uncharacterized protein. (698 aa)
	CHGG_04500	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (114 aa)
	CHGG_04440	TFIIB-type domain-containing protein. (353 aa)
	CHGG_04192	Protein kinase domain-containing protein. (327 aa)
	CHGG_05957	TFIIF_beta domain-containing protein. (260 aa)
	CHGG_05716	Uncharacterized protein. (808 aa)
	CHGG_03503	Acyl_transf_3 domain-containing protein. (451 aa)
	CHGG_03408	F-box domain-containing protein. (448 aa)
	CHGG_03122	DUF4211 domain-containing protein. (609 aa)
	CHGG_02746	PHD domain-containing protein. (795 aa)
	CHGG_02600	HTH TFE/IIEalpha-type domain-containing protein. (339 aa)
	CHGG_01655	Uncharacterized protein. (386 aa)
	CHGG_01375	DUF3591 domain-containing protein. (1126 aa)
	CHGG_01012	Uncharacterized protein. (1486 aa)
	CHGG_00894	RING-type domain-containing protein. (365 aa)
	CHGG_00881	Uncharacterized protein. (157 aa)
	CHGG_00838	TAFII55_N domain-containing protein. (529 aa)
	CHGG_00717	Uncharacterized protein. (87 aa)
	CHGG_00338	Helicase ATP-binding domain-containing protein. (979 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00338	CHGG_00838	Q2HHG6	Q2HG16	Helicase ATP-binding domain-containing protein.	TAFII55_N domain-containing protein.	0.652
CHGG_00338	CHGG_00881	Q2HHG6	Q2HFX3	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.652
CHGG_00338	CHGG_00894	Q2HHG6	Q2HFW0	Helicase ATP-binding domain-containing protein.	RING-type domain-containing protein.	0.955
CHGG_00338	CHGG_01012	Q2HHG6	Q2HFJ2	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.678
CHGG_00338	CHGG_01375	Q2HHG6	Q2HEH9	Helicase ATP-binding domain-containing protein.	DUF3591 domain-containing protein.	0.652
CHGG_00338	CHGG_01655	Q2HHG6	Q2HDP9	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.851
CHGG_00338	CHGG_02600	Q2HHG6	Q2HB04	Helicase ATP-binding domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.950
CHGG_00338	CHGG_02746	Q2HHG6	Q2HAK8	Helicase ATP-binding domain-containing protein.	PHD domain-containing protein.	0.953
CHGG_00338	CHGG_03122	Q2HHG6	Q2H9I2	Helicase ATP-binding domain-containing protein.	DUF4211 domain-containing protein.	0.496
CHGG_00338	CHGG_03503	Q2HHG6	Q2H8F1	Helicase ATP-binding domain-containing protein.	Acyl_transf_3 domain-containing protein.	0.604
CHGG_00338	CHGG_04192	Q2HHG6	Q2H204	Helicase ATP-binding domain-containing protein.	Protein kinase domain-containing protein.	0.860
CHGG_00338	CHGG_04440	Q2HHG6	Q2H1A6	Helicase ATP-binding domain-containing protein.	TFIIB-type domain-containing protein.	0.893
CHGG_00338	CHGG_04500	Q2HHG6	Q2H146	Helicase ATP-binding domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.783
CHGG_00338	CHGG_04784	Q2HHG6	Q2H0B2	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.871
CHGG_00338	CHGG_04942	Q2HHG6	Q2GZV4	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.783
CHGG_00338	CHGG_05716	Q2HHG6	Q2H6J9	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.967
CHGG_00338	CHGG_05957	Q2HHG6	Q2H5V8	Helicase ATP-binding domain-containing protein.	TFIIF_beta domain-containing protein.	0.860
CHGG_00338	CHGG_07212	Q2HHG6	Q2GXU2	Helicase ATP-binding domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.860
CHGG_00338	CHGG_07476	Q2HHG6	Q2GX28	Helicase ATP-binding domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.949
CHGG_00338	CHGG_07665	Q2HHG6	Q2GWI9	Helicase ATP-binding domain-containing protein.	TAF domain-containing protein.	0.670