(92 nodes) Mixed, incl. Proteasome, and ERAD pathway network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10928	Proteasome subunit beta. (212 aa)
	CHGG_10635	PRKCSH domain-containing protein. (572 aa)
	CHGG_10407	Proteasome endopeptidase complex. (277 aa)
	CHGG_10406	RING-CH-type domain-containing protein. (341 aa)
	CHGG_10381	Uncharacterized protein. (795 aa)
	CHGG_10367	ANK_REP_REGION domain-containing protein. (1400 aa)
	CHGG_10346	Uncharacterized protein. (598 aa)
	CHGG_10267	Uncharacterized protein. (651 aa)
	CHGG_10248	Uncharacterized protein. (333 aa)
	CHGG_10208	PCI domain-containing protein. (423 aa)
	CHGG_10110	ATPase_AAA_core domain-containing protein. (856 aa)
	CHGG_10034	Uncharacterized protein. (106 aa)
	CHGG_09826	26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1129 aa)
	CHGG_09641	AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
	CHGG_09624	PCI domain-containing protein. (532 aa)
	CHGG_09413	Proteasome subunit alpha type. (251 aa)
	CHGG_09299	Uncharacterized protein. (1783 aa)
	CHGG_09185	PCI domain-containing protein. (490 aa)
	CHGG_09115	Uncharacterized protein. (593 aa)
	CHGG_08754	AZUL domain-containing protein. (765 aa)
	CHGG_08307	AAA domain-containing protein; Belongs to the AAA ATPase family. (269 aa)
	CHGG_08072	Ufd2P_core domain-containing protein. (1109 aa)
	CHGG_07995	26S proteasome regulatory subunit rpn-8. (353 aa)
	CHGG_07892	AAA domain-containing protein; Belongs to the AAA ATPase family. (671 aa)
	CHGG_07776	Proteasome subunit alpha type. (267 aa)
	CHGG_07516	Uncharacterized protein. (371 aa)
	CHGG_07431	AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
	CHGG_07343	Peptidylprolyl isomerase. (116 aa)
	CHGG_07305	RING-type domain-containing protein. (869 aa)
	CHGG_07297	Ubiquitin carboxyl-terminal hydrolase. (339 aa)
	CHGG_06988	Uncharacterized protein. (295 aa)
	CHGG_06950	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (254 aa)
	CHGG_05075	AAA domain-containing protein. (980 aa)
	CHGG_05036	Uncharacterized protein. (2174 aa)
	CHGG_04807	Proteasome subunit alpha type. (245 aa)
	CHGG_04753	Uncharacterized protein. (779 aa)
	CHGG_04736	Ubiquitin carboxyl-terminal hydrolase. (248 aa)
	CHGG_04657	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (902 aa)
	CHGG_04469	AAA domain-containing protein; Belongs to the AAA ATPase family. (210 aa)
	CHGG_03776	Uncharacterized protein. (160 aa)
	CHGG_03735	ATPase_AAA_core domain-containing protein. (496 aa)
	CHGG_06797	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
	CHGG_06626	Ubiquitin carboxyl-terminal hydrolase. (554 aa)
	CHGG_06615	UAS domain-containing protein. (514 aa)
	CHGG_06441	UBX domain-containing protein. (435 aa)
	CHGG_06330	PCI domain-containing protein. (487 aa)
	CHGG_06284	Uncharacterized protein. (988 aa)
	CHGG_06158	Uncharacterized protein. (1494 aa)
	CHGG_06086	Uncharacterized protein. (808 aa)
	CHGG_05997	Proteasome subunit beta; Belongs to the peptidase T1B family. (275 aa)
	CHGG_05995	AAA domain-containing protein; Belongs to the AAA ATPase family. (391 aa)
	CHGG_05916	VWFA domain-containing protein. (292 aa)
	CHGG_05870	Uncharacterized protein. (614 aa)
	CHGG_05732	AAA domain-containing protein. (1559 aa)
	CHGG_05718	Proteasome endopeptidase complex. (269 aa)
	CHGG_05688	Uncharacterized protein. (947 aa)
	CHGG_05598	Uncharacterized protein. (222 aa)
	CHGG_05553	Uncharacterized protein. (493 aa)
	CHGG_03671	Uncharacterized protein. (1948 aa)
	CHGG_03255	RING-type domain-containing protein. (407 aa)
	CHGG_03219	Uncharacterized protein. (392 aa)
	CHGG_03010	Uncharacterized protein; Belongs to the AAA ATPase family. (821 aa)
	CHGG_02830	MPN domain-containing protein. (616 aa)
	CHGG_02727	Uncharacterized protein. (265 aa)
	CHGG_02628	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (260 aa)
	CHGG_02174	TGc domain-containing protein. (1028 aa)
	CHGG_02040	Uncharacterized protein. (587 aa)
	CHGG_01885	FK506-binding protein. (471 aa)
	CHGG_01720	Uncharacterized protein. (439 aa)
	CHGG_01685	TGc domain-containing protein. (352 aa)
	CHGG_01634	RPN13_C domain-containing protein. (387 aa)
	CHGG_01576	Uncharacterized protein. (192 aa)
	CHGG_01575	TUG-UBL1 domain-containing protein. (552 aa)
	CHGG_01544	Uncharacterized protein. (229 aa)
	CHGG_01438	AAA domain-containing protein. (401 aa)
	CHGG_01418	Proteasome subunit beta type 7. (272 aa)
	CHGG_01391	Uncharacterized protein. (895 aa)
	CHGG_01339	Uncharacterized protein. (403 aa)
	CHGG_01270	MPN domain-containing protein. (294 aa)
	CHGG_01208	UBX domain-containing protein. (537 aa)
	CHGG_01207	Uncharacterized protein. (1683 aa)
	CHGG_01147	Uncharacterized protein. (274 aa)
	CHGG_01018	DUF862 domain-containing protein. (252 aa)
	CHGG_00922	Ubiquitin carboxyl-terminal hydrolase. (217 aa)
	CHGG_00795	Proteasome subunit beta. (283 aa)
	CHGG_00785	Uncharacterized protein. (753 aa)
	CHGG_00512	Uncharacterized protein. (813 aa)
	CHGG_00410	PCI domain-containing protein. (382 aa)
	CHGG_00400	Uncharacterized protein. (441 aa)
	CHGG_00386	OTU domain-containing protein. (300 aa)
	CHGG_00376	CSN8_PSD8_EIF3K domain-containing protein. (283 aa)
	CHGG_00375	Uncharacterized protein. (885 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00375	CHGG_02628	Q2HHC9	Q2HAX6	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.809
CHGG_00375	CHGG_03010	Q2HHC9	Q2H9U4	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.401
CHGG_00375	CHGG_03255	Q2HHC9	Q2H949	Uncharacterized protein.	RING-type domain-containing protein.	0.614
CHGG_00375	CHGG_03735	Q2HHC9	Q2H3B1	Uncharacterized protein.	ATPase_AAA_core domain-containing protein.	0.401
CHGG_00375	CHGG_04753	Q2HHC9	Q2H0E3	Uncharacterized protein.	Uncharacterized protein.	0.401
CHGG_00375	CHGG_05036	Q2HHC9	Q2GZL0	Uncharacterized protein.	Uncharacterized protein.	0.571
CHGG_00375	CHGG_05075	Q2HHC9	Q2GZH1	Uncharacterized protein.	AAA domain-containing protein.	0.401
CHGG_00375	CHGG_05688	Q2HHC9	Q2H6M7	Uncharacterized protein.	Uncharacterized protein.	0.571
CHGG_00375	CHGG_05870	Q2HHC9	Q2H645	Uncharacterized protein.	Uncharacterized protein.	0.401
CHGG_00375	CHGG_06615	Q2HHC9	Q2H400	Uncharacterized protein.	UAS domain-containing protein.	0.481
CHGG_00375	CHGG_07305	Q2HHC9	Q2GXJ9	Uncharacterized protein.	RING-type domain-containing protein.	0.571
CHGG_00375	CHGG_10110	Q2HHC9	Q2GPJ4	Uncharacterized protein.	ATPase_AAA_core domain-containing protein.	0.401
CHGG_00375	CHGG_10635	Q2HHC9	Q2GN19	Uncharacterized protein.	PRKCSH domain-containing protein.	0.869
CHGG_00376	CHGG_00400	Q2HHC8	Q2HHA4	CSN8_PSD8_EIF3K domain-containing protein.	Uncharacterized protein.	0.919
CHGG_00376	CHGG_00410	Q2HHC8	Q2HH94	CSN8_PSD8_EIF3K domain-containing protein.	PCI domain-containing protein.	0.999
CHGG_00376	CHGG_00512	Q2HHC8	Q2HGZ2	CSN8_PSD8_EIF3K domain-containing protein.	Uncharacterized protein.	0.627
CHGG_00376	CHGG_00795	Q2HHC8	Q2HG59	CSN8_PSD8_EIF3K domain-containing protein.	Proteasome subunit beta.	0.987
CHGG_00376	CHGG_01018	Q2HHC8	Q2HFI6	CSN8_PSD8_EIF3K domain-containing protein.	DUF862 domain-containing protein.	0.857
CHGG_00376	CHGG_01147	Q2HHC8	Q2HF57	CSN8_PSD8_EIF3K domain-containing protein.	Uncharacterized protein.	0.995
CHGG_00376	CHGG_01207	Q2HHC8	Q2HEZ7	CSN8_PSD8_EIF3K domain-containing protein.	Uncharacterized protein.	0.909