(34 nodes) Neddylation, and Cullin network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_11121	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)
	CHGG_10344	Uncharacterized protein. (558 aa)
	CHGG_10145	WD_REPEATS_REGION domain-containing protein. (1029 aa)
	CHGG_09415	Uncharacterized protein. (1018 aa)
	CHGG_08516	Uncharacterized protein. (836 aa)
	CHGG_07693	TIP120 domain-containing protein. (1329 aa)
	CHGG_07437	F-box domain-containing protein. (772 aa)
	CHGG_04596	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (505 aa)
	CHGG_04203	CPSF_A domain-containing protein. (1127 aa)
	CHGG_04143	Uncharacterized protein. (154 aa)
	CHGG_03854	MPN domain-containing protein. (441 aa)
	CHGG_03817	CULLIN_2 domain-containing protein; Belongs to the cullin family. (724 aa)
	CHGG_06433	WD_REPEATS_REGION domain-containing protein. (603 aa)
	CHGG_06176	PCI domain-containing protein. (498 aa)
	CHGG_06152	Uncharacterized protein. (290 aa)
	CHGG_06002	PCI domain-containing protein. (399 aa)
	CHGG_05826	Uncharacterized protein. (87 aa)
	CHGG_05817	F-box domain-containing protein. (531 aa)
	CHGG_05725	Uncharacterized protein. (656 aa)
	CHGG_05316	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (327 aa)
	CHGG_03506	Uncharacterized protein. (644 aa)
	CHGG_03477	Uncharacterized protein. (779 aa)
	CHGG_03232	CULLIN_2 domain-containing protein; Belongs to the cullin family. (709 aa)
	CHGG_03043	Uncharacterized protein; Belongs to the SKP1 family. (170 aa)
	CHGG_02946	PCI domain-containing protein. (441 aa)
	CHGG_02552	WD_REPEATS_REGION domain-containing protein. (656 aa)
	CHGG_01777	PCI domain-containing protein. (386 aa)
	CHGG_01581	Ubiquitin-like domain-containing protein. (104 aa)
	CHGG_01165	ULP_PROTEASE domain-containing protein. (732 aa)
	CHGG_01136	CULLIN_2 domain-containing protein; Belongs to the cullin family. (822 aa)
	CHGG_01094	E2_bind domain-containing protein. (433 aa)
	CHGG_00888	F-box domain-containing protein. (522 aa)
	CHGG_00615	Uncharacterized protein. (470 aa)
	CHGG_00332	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (524 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00332	CHGG_00615	Q2HHH2	Q2HGN9	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.733
CHGG_00332	CHGG_01094	Q2HHH2	Q2HFB0	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	E2_bind domain-containing protein.	0.598
CHGG_00332	CHGG_01581	Q2HHH2	Q2HDX3	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Ubiquitin-like domain-containing protein.	0.642
CHGG_00332	CHGG_01777	Q2HHH2	Q2HDC7	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	PCI domain-containing protein.	0.771
CHGG_00332	CHGG_02552	Q2HHH2	Q2HB52	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	WD_REPEATS_REGION domain-containing protein.	0.697
CHGG_00332	CHGG_02946	Q2HHH2	Q2HA08	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	PCI domain-containing protein.	0.731
CHGG_00332	CHGG_03232	Q2HHH2	Q2H972	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.928
CHGG_00332	CHGG_03477	Q2HHH2	Q2H8H7	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.422
CHGG_00332	CHGG_03854	Q2HHH2	Q2H2Z2	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	MPN domain-containing protein.	0.682
CHGG_00332	CHGG_04203	Q2HHH2	Q2H1Z3	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	CPSF_A domain-containing protein.	0.986
CHGG_00332	CHGG_04596	Q2HHH2	Q2H0V0	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	0.603
CHGG_00332	CHGG_05826	Q2HHH2	Q2H689	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.866
CHGG_00332	CHGG_06002	Q2HHH2	Q2H5R3	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	PCI domain-containing protein.	0.768
CHGG_00332	CHGG_06176	Q2HHH2	Q2H589	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	PCI domain-containing protein.	0.762
CHGG_00332	CHGG_07693	Q2HHH2	Q2GWG1	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	TIP120 domain-containing protein.	0.682
CHGG_00332	CHGG_08516	Q2HHH2	Q2GU38	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.820
CHGG_00332	CHGG_10145	Q2HHH2	Q2GPF9	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	WD_REPEATS_REGION domain-containing protein.	0.422
CHGG_00332	CHGG_10344	Q2HHH2	Q2GNW0	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.745
CHGG_00332	CHGG_11121	Q2HHH2	Q2GLW2	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.589
CHGG_00615	CHGG_00332	Q2HGN9	Q2HHH2	Uncharacterized protein.	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	0.733