(35 nodes) Mixed, incl. MAPK cascade, and Activation of the AP-1 family of transcription factors network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10392	HPt domain-containing protein. (137 aa)
	CHGG_10198	TPR_REGION domain-containing protein. (883 aa)
	CHGG_10041	Uncharacterized protein. (60 aa)
	CHGG_09643	Uncharacterized protein. (627 aa)
	CHGG_09618	Protein kinase domain-containing protein. (1642 aa)
	CHGG_08306	Uncharacterized protein. (1030 aa)
	CHGG_08158	Uncharacterized protein. (213 aa)
	CHGG_07766	Uncharacterized protein. (637 aa)
	CHGG_07110	Uncharacterized protein. (475 aa)
	CHGG_06954	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
	HOG1	Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (360 aa)
	SHO1	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (297 aa)
	CHGG_06648	Response regulatory domain-containing protein. (819 aa)
	CHGG_06190	Protein kinase domain-containing protein. (605 aa)
	CHGG_06096	Uncharacterized protein. (509 aa)
	CHGG_05813	Uncharacterized protein. (911 aa)
	CHGG_05682	Protein kinase domain-containing protein. (510 aa)
	CHGG_05623	WD_REPEATS_REGION domain-containing protein. (619 aa)
	CHGG_03309	Uncharacterized protein. (865 aa)
	CHGG_03123	Uncharacterized protein. (447 aa)
	CHGG_03110	PPM-type phosphatase domain-containing protein. (580 aa)
	CHGG_02925	C2H2-type domain-containing protein. (660 aa)
	CHGG_02313	Uncharacterized protein. (1233 aa)
	CHGG_01521	Uncharacterized protein. (1270 aa)
	CHGG_01378	MADS-box domain-containing protein. (564 aa)
	CHGG_01315	BZIP domain-containing protein. (414 aa)
	CHGG_00856	Uncharacterized protein. (825 aa)
	CHGG_00809	Protein kinase domain-containing protein. (1152 aa)
	CHGG_00632	BZIP domain-containing protein. (538 aa)
	CHGG_00598	Uncharacterized protein. (396 aa)
	CHGG_00531	Protein kinase domain-containing protein. (397 aa)
	CHGG_00520	PPM-type phosphatase domain-containing protein. (440 aa)
	CHGG_00513	Uncharacterized protein. (1172 aa)
	CHGG_00440	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (353 aa)
	CHGG_00092	Uncharacterized protein. (170 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00092	CHGG_00520	Q2HI62	Q2HGY4	Uncharacterized protein.	PPM-type phosphatase domain-containing protein.	0.479
CHGG_00092	CHGG_00531	Q2HI62	Q2HGX3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.680
CHGG_00092	CHGG_00632	Q2HI62	Q2HGM2	Uncharacterized protein.	BZIP domain-containing protein.	0.586
CHGG_00092	CHGG_00856	Q2HI62	Q2HFZ8	Uncharacterized protein.	Uncharacterized protein.	0.634
CHGG_00092	CHGG_01315	Q2HI62	Q2HEN9	Uncharacterized protein.	BZIP domain-containing protein.	0.580
CHGG_00092	CHGG_01378	Q2HI62	Q2HEH6	Uncharacterized protein.	MADS-box domain-containing protein.	0.837
CHGG_00092	CHGG_03110	Q2HI62	Q2H9J4	Uncharacterized protein.	PPM-type phosphatase domain-containing protein.	0.599
CHGG_00092	CHGG_05682	Q2HI62	Q2H6N3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.867
CHGG_00092	CHGG_05813	Q2HI62	Q2H6A2	Uncharacterized protein.	Uncharacterized protein.	0.872
CHGG_00092	CHGG_06096	Q2HI62	Q2H5G9	Uncharacterized protein.	Uncharacterized protein.	0.508
CHGG_00092	CHGG_06190	Q2HI62	Q2H575	Uncharacterized protein.	Protein kinase domain-containing protein.	0.679
CHGG_00092	CHGG_07110	Q2HI62	Q2GY44	Uncharacterized protein.	Uncharacterized protein.	0.586
CHGG_00092	CHGG_08158	Q2HI62	Q2GV46	Uncharacterized protein.	Uncharacterized protein.	0.508
CHGG_00092	CHGG_08306	Q2HI62	Q2GUP8	Uncharacterized protein.	Uncharacterized protein.	0.707
CHGG_00092	CHGG_09618	Q2HI62	Q2GQY6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.726
CHGG_00092	CHGG_09643	Q2HI62	Q2GQW1	Uncharacterized protein.	Uncharacterized protein.	0.618
CHGG_00440	CHGG_00520	Q2HH64	Q2HGY4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	PPM-type phosphatase domain-containing protein.	0.479
CHGG_00440	CHGG_00531	Q2HH64	Q2HGX3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.992
CHGG_00440	CHGG_00632	Q2HH64	Q2HGM2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.582
CHGG_00440	CHGG_01315	Q2HH64	Q2HEN9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.589