(54 nodes) Mixed, incl. Amino acids regulate mTORC1, and VEGFR2 mediated vascular permeability network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10219	Uncharacterized protein. (233 aa)
	CHGG_10171	HSF_DOMAIN domain-containing protein. (650 aa)
	CHGG_09892	ANK_REP_REGION domain-containing protein. (245 aa)
	CHGG_09642	UDENN FLCN/SMCR8-type domain-containing protein. (381 aa)
	CHGG_09635	HRDC domain-containing protein. (827 aa)
	CHGG_09145	Protein kinase domain-containing protein. (389 aa)
	CHGG_08787	VWFA domain-containing protein. (777 aa)
	CHGG_08720	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2208 aa)
	CHGG_08690	mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (168 aa)
	CHGG_08366	Lipase_3 domain-containing protein. (307 aa)
	CHGG_08247	Protein kinase domain-containing protein. (689 aa)
	CHGG_07991	Uncharacterized protein. (881 aa)
	CHGG_07826	Peptidase_S24 domain-containing protein. (207 aa)
	CHGG_07796	Uncharacterized protein. (188 aa)
	CHGG_07584	Uncharacterized protein. (222 aa)
	CHGG_07517	Uncharacterized protein. (407 aa)
	CHGG_07345	Uncharacterized protein. (252 aa)
	CHGG_07177	Rap-GAP domain-containing protein. (1506 aa)
	CHGG_07166	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
	CHGG_07081	WD_REPEATS_REGION domain-containing protein. (305 aa)
	CHGG_05051	Fungal_trans domain-containing protein. (487 aa)
	IML1	Vacuolar membrane-associated protein IML1. (1889 aa)
	CHGG_04415	Non-specific serine/threonine protein kinase. (641 aa)
	CHGG_04163	Uncharacterized protein. (1064 aa)
	CHGG_04090	Fungal_trans domain-containing protein. (1090 aa)
	CHGG_03962	Hist_deacetyl domain-containing protein. (1145 aa)
	CHGG_06421	Uncharacterized protein. (1401 aa)
	CHGG_06311	Choline_kin_N domain-containing protein. (803 aa)
	CHGG_06257	WD_REPEATS_REGION domain-containing protein. (1413 aa)
	CHGG_06208	EST1_DNA_bind domain-containing protein. (821 aa)
	CHGG_05981	Uncharacterized protein. (1871 aa)
	CHGG_05805	Zinc_ribbon_16 domain-containing protein. (873 aa)
	CHGG_05547	Uncharacterized protein. (1509 aa)
	CHGG_02969	Uncharacterized protein. (856 aa)
	CHGG_02954	Uncharacterized protein. (343 aa)
	CHGG_02915	Uncharacterized protein. (720 aa)
	CHGG_02836	Uncharacterized protein. (581 aa)
	CHGG_02773	Uncharacterized protein. (437 aa)
	CHGG_02772	Uncharacterized protein. (904 aa)
	CHGG_02462	Protein kinase domain-containing protein. (420 aa)
	CHGG_02442	Methyltranfer_dom domain-containing protein. (442 aa)
	CHGG_02332	Protein kinase domain-containing protein. (495 aa)
	CHGG_02246	Uncharacterized protein. (349 aa)
	CHGG_02045	WD_REPEATS_REGION domain-containing protein. (1256 aa)
	CHGG_01748	Uncharacterized protein. (286 aa)
	CHGG_01571	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (266 aa)
	CHGG_01471	Uncharacterized protein. (877 aa)
	CHGG_01446	DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (264 aa)
	CHGG_01399	Non-specific serine/threonine protein kinase. (650 aa)
	CHGG_01397	Uncharacterized protein. (534 aa)
	CHGG_01231	Uncharacterized protein. (178 aa)
	CHGG_01095	Telomere_reg-2 domain-containing protein. (903 aa)
	CHGG_00398	Response regulatory domain-containing protein. (658 aa)
	CHGG_00288	Protein kinase domain-containing protein. (733 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00288	CHGG_00398	Q2HHL6	Q2HHA6	Protein kinase domain-containing protein.	Response regulatory domain-containing protein.	0.505
CHGG_00398	CHGG_00288	Q2HHA6	Q2HHL6	Response regulatory domain-containing protein.	Protein kinase domain-containing protein.	0.505
CHGG_00398	CHGG_01446	Q2HHA6	Q2HEA8	Response regulatory domain-containing protein.	DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family.	0.783
CHGG_00398	CHGG_01571	Q2HHA6	Q2HDY3	Response regulatory domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.783
CHGG_00398	CHGG_02246	Q2HHA6	Q2HC08	Response regulatory domain-containing protein.	Uncharacterized protein.	0.505
CHGG_00398	CHGG_02836	Q2HHA6	Q2HAB8	Response regulatory domain-containing protein.	Uncharacterized protein.	0.543
CHGG_00398	CHGG_03962	Q2HHA6	Q2H2N4	Response regulatory domain-containing protein.	Hist_deacetyl domain-containing protein.	0.946
CHGG_00398	CHGG_06208	Q2HHA6	Q2H557	Response regulatory domain-containing protein.	EST1_DNA_bind domain-containing protein.	0.505
CHGG_00398	CHGG_06257	Q2HHA6	Q2H508	Response regulatory domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.951
CHGG_00398	CHGG_07081	Q2HHA6	Q2GY73	Response regulatory domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.939
CHGG_00398	CHGG_07166	Q2HHA6	Q2GXY8	Response regulatory domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.948
CHGG_00398	CHGG_07345	Q2HHA6	Q2GXF9	Response regulatory domain-containing protein.	Uncharacterized protein.	0.982
CHGG_00398	CHGG_08720	Q2HHA6	Q2GTI4	Response regulatory domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.785
CHGG_00398	CHGG_08787	Q2HHA6	Q2GTB7	Response regulatory domain-containing protein.	VWFA domain-containing protein.	0.505
CHGG_00398	CHGG_09635	Q2HHA6	Q2GQW9	Response regulatory domain-containing protein.	HRDC domain-containing protein.	0.785
CHGG_00398	CHGG_10171	Q2HHA6	Q2GPD3	Response regulatory domain-containing protein.	HSF_DOMAIN domain-containing protein.	0.641
CHGG_00398	CHGG_10219	Q2HHA6	Q2GP85	Response regulatory domain-containing protein.	Uncharacterized protein.	0.505
CHGG_01095	CHGG_02915	Q2HFA9	Q2HA39	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.540
CHGG_01095	CHGG_02954	Q2HFA9	Q2HA00	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.428
CHGG_01095	CHGG_02969	Q2HFA9	Q2H9Y5	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.997