(24 nodes) Mixed, incl. COPI vesicle coat, and Regulation of ARF protein signal transduction network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10412	ER lumen protein-retaining receptor. (215 aa)
	CHGG_08644	GOLD domain-containing protein. (219 aa)
	CHGG_07806	Uncharacterized protein. (1447 aa)
	CHGG_07253	GOLD domain-containing protein. (210 aa)
	CHGG_05131	SEC7 domain-containing protein. (1811 aa)
	CHGG_04577	SEC7 domain-containing protein. (1612 aa)
	CHGG_04516	Arf-GAP domain-containing protein. (332 aa)
	CHGG_04459	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (960 aa)
	CHGG_04058	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (853 aa)
	CHGG_03912	Arf-GAP domain-containing protein. (488 aa)
	CHGG_06556	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa)
	CHGG_03152	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (513 aa)
	CHGG_03145	Uncharacterized protein. (560 aa)
	CHGG_03041	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	CHGG_01793	Uncharacterized protein. (953 aa)
	CHGG_01645	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	CHGG_01644	GOLD domain-containing protein. (201 aa)
	CHGG_01592	Uncharacterized protein. (263 aa)
	CHGG_01416	Uncharacterized protein. (331 aa)
	CHGG_01087	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (200 aa)
	CHGG_00702	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (294 aa)
	CHGG_00629	GOLD domain-containing protein. (220 aa)
	CHGG_00377	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1236 aa)
	CHGG_00371	SEC7 domain-containing protein. (1591 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00371	CHGG_01645	Q2HHD3	Q2HDQ9	SEC7 domain-containing protein.	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family.	0.549
CHGG_00371	CHGG_03041	Q2HHD3	Q2H9R3	SEC7 domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.684
CHGG_00371	CHGG_04577	Q2HHD3	Q2H0W9	SEC7 domain-containing protein.	SEC7 domain-containing protein.	0.866
CHGG_00371	CHGG_05131	Q2HHD3	Q2GZB5	SEC7 domain-containing protein.	SEC7 domain-containing protein.	0.817
CHGG_00371	CHGG_07806	Q2HHD3	Q2GW48	SEC7 domain-containing protein.	Uncharacterized protein.	0.463
CHGG_00377	CHGG_00629	Q2HHC7	Q2HGM5	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	GOLD domain-containing protein.	0.816
CHGG_00377	CHGG_00702	Q2HHC7	Q2HGF2	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.	0.999
CHGG_00377	CHGG_01087	Q2HHC7	Q2HFB7	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.992
CHGG_00377	CHGG_01416	Q2HHC7	Q2HED8	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Uncharacterized protein.	0.696
CHGG_00377	CHGG_01592	Q2HHC7	Q2HDW2	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Uncharacterized protein.	0.744
CHGG_00377	CHGG_01644	Q2HHC7	Q2HDR0	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	GOLD domain-containing protein.	0.715
CHGG_00377	CHGG_01645	Q2HHC7	Q2HDQ9	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family.	0.735
CHGG_00377	CHGG_01793	Q2HHC7	Q2HDB1	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Uncharacterized protein.	0.726
CHGG_00377	CHGG_03152	Q2HHC7	Q2H9F2	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.997
CHGG_00377	CHGG_03912	Q2HHC7	Q2H2T4	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Arf-GAP domain-containing protein.	0.964
CHGG_00377	CHGG_04058	Q2HHC7	Q2H2D8	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.999
CHGG_00377	CHGG_04459	Q2HHC7	Q2H187	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.998
CHGG_00377	CHGG_04516	Q2HHC7	Q2H130	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Arf-GAP domain-containing protein.	0.712
CHGG_00377	CHGG_04577	Q2HHC7	Q2H0W9	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	SEC7 domain-containing protein.	0.846
CHGG_00377	CHGG_06556	Q2HHC7	Q2H459	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.996