14 items (Chaetomium globosum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10193	AMP-binding_C domain-containing protein. (140 aa)
	CHGG_09134	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (447 aa)
	CHGG_05132	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (458 aa)
	CHGG_04989	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (460 aa)
	CHGG_06142	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (378 aa)
	CHGG_05761	Uncharacterized protein. (430 aa)
	CHGG_05724	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (412 aa)
	CHGG_02760	Probable acetate kinase. (459 aa)
	CHGG_02507	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (532 aa)
	CHGG_02144	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (394 aa)
	CHGG_00580	Uncharacterized protein. (697 aa)
	CHGG_00469	Lipoyl-binding domain-containing protein. (425 aa)
	CHGG_00017	Isochorismatase domain-containing protein. (192 aa)
	CHGG_10425	Citrate_bind domain-containing protein. (482 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00017	CHGG_05132	Q2HID7	Q2GZB4	Isochorismatase domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.878
CHGG_00017	CHGG_05724	Q2HID7	Q2H6J1	Isochorismatase domain-containing protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.750
CHGG_00017	CHGG_05761	Q2HID7	Q2H6F4	Isochorismatase domain-containing protein.	Uncharacterized protein.	0.792
CHGG_00017	CHGG_06142	Q2HID7	Q2H5C3	Isochorismatase domain-containing protein.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.902
CHGG_00017	CHGG_09134	Q2HID7	Q2GSC0	Isochorismatase domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.542
CHGG_00017	CHGG_10425	Q2HID7	Q2GNM9	Isochorismatase domain-containing protein.	Citrate_bind domain-containing protein.	0.703
CHGG_00469	CHGG_05132	Q2HH35	Q2GZB4	Lipoyl-binding domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.896
CHGG_00469	CHGG_05724	Q2HH35	Q2H6J1	Lipoyl-binding domain-containing protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.794
CHGG_00469	CHGG_05761	Q2HH35	Q2H6F4	Lipoyl-binding domain-containing protein.	Uncharacterized protein.	0.849
CHGG_00469	CHGG_06142	Q2HH35	Q2H5C3	Lipoyl-binding domain-containing protein.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.919
CHGG_00469	CHGG_09134	Q2HH35	Q2GSC0	Lipoyl-binding domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.811
CHGG_00469	CHGG_10425	Q2HH35	Q2GNM9	Lipoyl-binding domain-containing protein.	Citrate_bind domain-containing protein.	0.703
CHGG_00580	CHGG_02760	Q2HGS4	Q2HAJ4	Uncharacterized protein.	Probable acetate kinase.	0.806
CHGG_00580	CHGG_05132	Q2HGS4	Q2GZB4	Uncharacterized protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.586
CHGG_00580	CHGG_05724	Q2HGS4	Q2H6J1	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.611
CHGG_00580	CHGG_05761	Q2HGS4	Q2H6F4	Uncharacterized protein.	Uncharacterized protein.	0.562
CHGG_00580	CHGG_06142	Q2HGS4	Q2H5C3	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.595
CHGG_00580	CHGG_09134	Q2HGS4	Q2GSC0	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.442
CHGG_00580	CHGG_10193	Q2HGS4	Q2GPB1	Uncharacterized protein.	AMP-binding_C domain-containing protein.	0.830
CHGG_02144	CHGG_02507	Q2HCB0	Q2HB97	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.990