(111 nodes) Ubiquitin-like protein transferase activity network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_08657	E3 ubiquitin-protein ligase. (778 aa)
	CHGG_08740	UBIQUITIN_CONJUGAT_2 domain-containing protein. (299 aa)
	CHGG_08812	Uncharacterized protein. (292 aa)
	CHGG_08925	HECT domain-containing protein. (1033 aa)
	CHGG_09083	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	CHGG_09108	Uncharacterized protein. (770 aa)
	CHGG_09144	RING-type domain-containing protein. (211 aa)
	CHGG_09177	SP-RING-type domain-containing protein. (372 aa)
	CHGG_09209	HECT domain-containing protein. (1332 aa)
	CHGG_09212	Uncharacterized protein. (628 aa)
	CHGG_09245	Uncharacterized protein. (2710 aa)
	CHGG_09260	HECT domain-containing protein. (1955 aa)
	CHGG_09269	Uncharacterized protein. (270 aa)
	CHGG_09306	Ubiquitin-conjugating enzyme. (134 aa)
	CHGG_09371	Uncharacterized protein. (946 aa)
	CHGG_09404	RING-type domain-containing protein. (1130 aa)
	CHGG_09607	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	CHGG_09625	Uncharacterized protein. (386 aa)
	CHGG_09740	RBR-type E3 ubiquitin transferase. (531 aa)
	CHGG_10164	HECT domain-containing protein. (3925 aa)
	CHGG_10242	Uncharacterized protein. (594 aa)
	CHGG_10358	RING-type domain-containing protein. (540 aa)
	CHGG_10507	E3 ubiquitin-protein ligase PEP5. (971 aa)
	CHGG_10569	Uncharacterized protein. (605 aa)
	CHGG_10570	RBR-type E3 ubiquitin transferase. (623 aa)
	CHGG_10843	Uncharacterized protein. (323 aa)
	CHGG_10844	RING-type domain-containing protein. (102 aa)
	CHGG_10970	RING-type domain-containing protein. (801 aa)
	CHGG_11121	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)
	CHGG_07720	UBIQUITIN_CONJUGAT_2 domain-containing protein. (237 aa)
	CHGG_07688	RBR-type E3 ubiquitin transferase. (470 aa)
	CHGG_07477	UBIQUITIN_CONJUGAT_2 domain-containing protein. (973 aa)
	CHGG_07430	UBIQUITIN_CONJUGAT_2 domain-containing protein. (240 aa)
	CHGG_07305	RING-type domain-containing protein. (869 aa)
	CHGG_07210	Uncharacterized protein. (1480 aa)
	CHGG_07192	Uncharacterized protein. (651 aa)
	CHGG_07149	Uncharacterized protein. (639 aa)
	CHGG_07137	Uncharacterized protein. (707 aa)
	CHGG_07083	FHA domain-containing protein. (660 aa)
	CHGG_07043	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	CHGG_07017	UBR-type domain-containing protein. (528 aa)
	CHGG_06956	SP-RING-type domain-containing protein. (918 aa)
	CHGG_05110	NmrA domain-containing protein. (259 aa)
	CHGG_05036	Uncharacterized protein. (2174 aa)
	CHGG_04866	Pex2_Pex12 domain-containing protein. (423 aa)
	CHGG_04848	RING-type domain-containing protein. (633 aa)
	CHGG_04690	UBIQUITIN_CONJUGAT_2 domain-containing protein. (956 aa)
	CHGG_04633	Uncharacterized protein. (955 aa)
	CHGG_04537	Uncharacterized protein. (896 aa)
	CHGG_04530	Uncharacterized protein. (354 aa)
	CHGG_04528	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	CHGG_04386	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	CHGG_04296	UBIQUITIN_CONJUGAT_2 domain-containing protein. (189 aa)
	CHGG_04245	Uncharacterized protein. (285 aa)
	CHGG_04169	Uncharacterized protein. (889 aa)
	CHGG_04113	Uncharacterized protein. (1440 aa)
	CHGG_03860	Uncharacterized protein. (179 aa)
	CHGG_03836	IBR domain-containing protein. (680 aa)
	CHGG_03809	Uncharacterized protein. (822 aa)
	ATG3	Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of [...] (338 aa)
	CHGG_06580	RING-type domain-containing protein. (861 aa)
	CHGG_06422	UBIQUITIN_CONJUGAT_2 domain-containing protein. (113 aa)
	CHGG_06369	RBR-type E3 ubiquitin transferase. (779 aa)
	CHGG_06108	HET domain-containing protein. (572 aa)
	CHGG_05966	Uncharacterized protein. (180 aa)
	CHGG_05936	RING-type domain-containing protein. (837 aa)
	CHGG_05865	RING-type domain-containing protein. (207 aa)
	CHGG_05826	Uncharacterized protein. (87 aa)
	CHGG_05688	Uncharacterized protein. (947 aa)
	CHGG_05631	Uncharacterized protein. (470 aa)
	CHGG_05608	Uncharacterized protein. (597 aa)
	CHGG_05563	RING-type domain-containing protein. (528 aa)
	CHGG_05384	WD_REPEATS_REGION domain-containing protein. (807 aa)
	CHGG_03301	WHIM1 domain-containing protein. (641 aa)
	CHGG_03255	RING-type domain-containing protein. (407 aa)
	CHGG_03221	E3 ubiquitin protein ligase. (694 aa)
	FYV10	Protein FYV10; Involved in the proteasome-dependent degradation of fructose- 1,6-bisphosphatase; Belongs to the FYV10 family. (441 aa)
	CHGG_03193	zf-NOSIP domain-containing protein. (189 aa)
	CHGG_03090	FHA domain-containing protein. (623 aa)
	CHGG_03055	Uncharacterized protein. (139 aa)
	CHGG_02823	UBIQUITIN_CONJUGAT_2 domain-containing protein. (422 aa)
	CHGG_02578	UBIQUITIN_CONJUGAT_2 domain-containing protein. (318 aa)
	CHGG_02534	Uncharacterized protein. (814 aa)
	CHGG_02521	RBR-type E3 ubiquitin transferase. (614 aa)
	CHGG_02484	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	CHGG_02219	Uncharacterized protein. (916 aa)
	CHGG_02076	Uncharacterized protein. (947 aa)
	CHGG_02065	Uncharacterized protein. (150 aa)
	CHGG_01917	CTLH domain-containing protein. (473 aa)
	CHGG_01887	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2143 aa)
	CHGG_01845	RING-type domain-containing protein. (370 aa)
	CHGG_01780	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
	CHGG_01754	RING-type domain-containing protein. (552 aa)
	CHGG_01636	UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
	CHGG_01625	Uncharacterized protein. (698 aa)
	CHGG_01619	UBIQUITIN_CONJUGAT_2 domain-containing protein. (73 aa)
	CHGG_01556	Uncharacterized protein. (223 aa)
	CHGG_01391	Uncharacterized protein. (895 aa)
	CHGG_01369	RING-type domain-containing protein. (507 aa)
	CHGG_01091	Uncharacterized protein. (667 aa)
	CHGG_01016	RBR-type E3 ubiquitin transferase. (825 aa)
	CHGG_00972	Uncharacterized protein. (1109 aa)
	ATG5	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1- like activating enzyme and ATG10 as an E2- [...] (278 aa)
	CHGG_00462	SPX domain-containing protein. (277 aa)
	CHGG_00049	Uncharacterized protein. (619 aa)
	CHGG_07874	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1252 aa)
	CHGG_07937	Uncharacterized protein. (703 aa)
	CHGG_07951	Uncharacterized protein. (1078 aa)
	CHGG_08072	Ufd2P_core domain-containing protein. (1109 aa)
	CHGG_08074	Uncharacterized protein. (447 aa)
	CHGG_08700	Helicase ATP-binding domain-containing protein. (1996 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG3	ATG5	Q2H427	Q2HGZ8	Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of [...]	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1- like activating enzyme and ATG10 as an E2- [...]	0.993
ATG3	CHGG_01556	Q2H427	Q2HDZ8	Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of [...]	Uncharacterized protein.	0.600
ATG5	ATG3	Q2HGZ8	Q2H427	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1- like activating enzyme and ATG10 as an E2- [...]	Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of [...]	0.993
ATG5	CHGG_01556	Q2HGZ8	Q2HDZ8	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1- like activating enzyme and ATG10 as an E2- [...]	Uncharacterized protein.	0.812
CHGG_00049	CHGG_09260	Q2HIA5	Q2GRZ4	Uncharacterized protein.	HECT domain-containing protein.	0.973
CHGG_00462	CHGG_05631	Q2HH42	Q2H6T4	SPX domain-containing protein.	Uncharacterized protein.	0.525
CHGG_00462	CHGG_06422	Q2HH42	Q2H4J3	SPX domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.593
CHGG_00462	CHGG_06956	Q2HH42	Q2GYJ8	SPX domain-containing protein.	SP-RING-type domain-containing protein.	0.525
CHGG_00462	CHGG_07043	Q2HH42	Q2GYB1	SPX domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.452
CHGG_00462	CHGG_09260	Q2HH42	Q2GRZ4	SPX domain-containing protein.	HECT domain-containing protein.	0.642
CHGG_00462	CHGG_09306	Q2HH42	Q2GRU8	SPX domain-containing protein.	Ubiquitin-conjugating enzyme.	0.629
CHGG_00462	CHGG_11121	Q2HH42	Q2GLW2	SPX domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.518
CHGG_01016	CHGG_04169	Q2HFI8	Q2H227	RBR-type E3 ubiquitin transferase.	Uncharacterized protein.	0.404
CHGG_01016	CHGG_05826	Q2HFI8	Q2H689	RBR-type E3 ubiquitin transferase.	Uncharacterized protein.	0.533
CHGG_01016	CHGG_07477	Q2HFI8	Q2GX27	RBR-type E3 ubiquitin transferase.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.675
CHGG_01016	CHGG_09260	Q2HFI8	Q2GRZ4	RBR-type E3 ubiquitin transferase.	HECT domain-containing protein.	0.666
CHGG_01091	CHGG_01636	Q2HFB3	Q2HDR8	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.432
CHGG_01091	CHGG_02484	Q2HFB3	Q2HBC0	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.603
CHGG_01091	CHGG_02578	Q2HFB3	Q2HB26	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.709
CHGG_01091	CHGG_02823	Q2HFB3	Q2HAD1	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.466