(8 nodes) Eukaryotic translation initiation factor 4F complex network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_07151	Telo_bind domain-containing protein. (1637 aa)
	CHGG_04228	Uncharacterized protein. (365 aa)
	CHGG_05567	MIF4G domain-containing protein. (1512 aa)
	CHGG_01676	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (251 aa)
	TIF1	ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (397 aa)
	CHGG_03672	Uncharacterized protein. (1206 aa)
	CHGG_02545	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (281 aa)
	CHGG_02500	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (415 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_01676	CHGG_02500	Q2HDM8	Q2HBA4	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.809
CHGG_01676	CHGG_02545	Q2HDM8	Q2HB59	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.424
CHGG_01676	CHGG_03672	Q2HDM8	Q2H7Y2	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.697
CHGG_01676	CHGG_04228	Q2HDM8	Q2H1W8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.966
CHGG_01676	CHGG_05567	Q2HDM8	Q2H6Z8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	MIF4G domain-containing protein.	0.983
CHGG_01676	CHGG_07151	Q2HDM8	Q2GY03	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Telo_bind domain-containing protein.	0.539
CHGG_01676	TIF1	Q2HDM8	Q2HFP1	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.971
CHGG_02500	CHGG_01676	Q2HBA4	Q2HDM8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.809
CHGG_02500	CHGG_04228	Q2HBA4	Q2H1W8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.603
CHGG_02500	CHGG_05567	Q2HBA4	Q2H6Z8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	MIF4G domain-containing protein.	0.836
CHGG_02500	TIF1	Q2HBA4	Q2HFP1	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.411
CHGG_02545	CHGG_01676	Q2HB59	Q2HDM8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.424
CHGG_02545	CHGG_03672	Q2HB59	Q2H7Y2	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.697
CHGG_02545	CHGG_04228	Q2HB59	Q2H1W8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.697
CHGG_02545	CHGG_05567	Q2HB59	Q2H6Z8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	MIF4G domain-containing protein.	0.697
CHGG_02545	TIF1	Q2HB59	Q2HFP1	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.839
CHGG_03672	CHGG_01676	Q2H7Y2	Q2HDM8	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.697
CHGG_03672	CHGG_02545	Q2H7Y2	Q2HB59	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.697
CHGG_03672	TIF1	Q2H7Y2	Q2HFP1	Uncharacterized protein.	ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.901
CHGG_04228	CHGG_01676	Q2H1W8	Q2HDM8	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.966