(37 nodes) Short-chain dehydrogenase/reductase, conserved site network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_10550	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
	CHGG_10029	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
	CHGG_09930	Uncharacterized protein. (268 aa)
	CHGG_09887	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (390 aa)
	CHGG_09818	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
	CHGG_09250	Uncharacterized protein. (340 aa)
	CHGG_09196	Uncharacterized protein. (363 aa)
	CHGG_08416	Uncharacterized protein. (244 aa)
	CHGG_08358	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (273 aa)
	CHGG_08049	Uncharacterized protein. (304 aa)
	CHGG_07314	Uncharacterized protein. (283 aa)
	CHGG_07255	Uncharacterized protein. (295 aa)
	CHGG_07001	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (281 aa)
	CHGG_04924	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (291 aa)
	CHGG_04591	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (220 aa)
	CHGG_04243	Uncharacterized protein. (246 aa)
	CHGG_04239	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (342 aa)
	CHGG_04109	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa)
	CHGG_03832	Peroxisomal hydratase-dehydrogenase-epimerase. (894 aa)
	CHGG_03731	Uncharacterized protein. (239 aa)
	CHGG_06707	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)
	CHGG_06697	Uncharacterized protein. (285 aa)
	CHGG_06640	Uncharacterized protein. (256 aa)
	CHGG_06529	Uncharacterized protein. (269 aa)
	CHGG_06217	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
	CHGG_06026	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (296 aa)
	CHGG_05734	Uncharacterized protein. (283 aa)
	CHGG_02400	Tetrahydroxynaphthalene reductase. (283 aa)
	CHGG_02032	Uncharacterized protein. (295 aa)
	CHGG_01966	Uncharacterized protein. (244 aa)
	CHGG_01895	Uncharacterized protein. (259 aa)
	CHGG_01894	Uncharacterized protein. (1052 aa)
	CHGG_01739	Uncharacterized protein. (324 aa)
	CHGG_00753	Uncharacterized protein. (299 aa)
	CHGG_00372	Uncharacterized protein. (742 aa)
	CHGG_00265	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (297 aa)
	CHGG_00197	Uncharacterized protein. (302 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00372	CHGG_05734	Q2HHD2	Q2H6I1	Uncharacterized protein.	Uncharacterized protein.	0.710
CHGG_02400	CHGG_03832	Q2HBK4	Q2H314	Tetrahydroxynaphthalene reductase.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.417
CHGG_02400	CHGG_04239	Q2HBK4	Q2H1V7	Tetrahydroxynaphthalene reductase.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.535
CHGG_02400	CHGG_04924	Q2HBK4	Q2GZX2	Tetrahydroxynaphthalene reductase.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.544
CHGG_02400	CHGG_10550	Q2HBK4	Q2GNA4	Tetrahydroxynaphthalene reductase.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.573
CHGG_03832	CHGG_02400	Q2H314	Q2HBK4	Peroxisomal hydratase-dehydrogenase-epimerase.	Tetrahydroxynaphthalene reductase.	0.417
CHGG_03832	CHGG_04591	Q2H314	Q2H0V5	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.428
CHGG_03832	CHGG_05734	Q2H314	Q2H6I1	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein.	0.910
CHGG_03832	CHGG_07314	Q2H314	Q2GXJ0	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein.	0.588
CHGG_03832	CHGG_08416	Q2H314	Q2GUD8	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein.	0.417
CHGG_03832	CHGG_09930	Q2H314	Q2GQ24	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein.	0.417
CHGG_03832	CHGG_10550	Q2H314	Q2GNA4	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.417
CHGG_04239	CHGG_02400	Q2H1V7	Q2HBK4	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Tetrahydroxynaphthalene reductase.	0.535
CHGG_04239	CHGG_04591	Q2H1V7	Q2H0V5	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.809
CHGG_04239	CHGG_04924	Q2H1V7	Q2GZX2	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.808
CHGG_04239	CHGG_05734	Q2H1V7	Q2H6I1	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.686
CHGG_04239	CHGG_06640	Q2H1V7	Q2H3X5	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.541
CHGG_04239	CHGG_08416	Q2H1V7	Q2GUD8	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.535
CHGG_04239	CHGG_09930	Q2H1V7	Q2GQ24	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.808
CHGG_04239	CHGG_10550	Q2H1V7	Q2GNA4	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.808