(38 nodes) Lysine biosynthesis network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_08842	Uncharacterized protein. (475 aa)
	CHGG_11053	MFS domain-containing protein. (467 aa)
	CHGG_10806	MFS domain-containing protein. (507 aa)
	CHGG_10667	MFS domain-containing protein. (501 aa)
	LYS4	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (797 aa)
	CHGG_09757	Uncharacterized protein. (182 aa)
	CHGG_09677	Uncharacterized protein. (294 aa)
	CHGG_09403	Uncharacterized protein. (323 aa)
	CHGG_09169	Homoserine dehydrogenase. (369 aa)
	CHGG_08832	Uncharacterized protein. (340 aa)
	CHGG_08479	MFS domain-containing protein. (502 aa)
	CHGG_07330	Uncharacterized protein. (605 aa)
	CHGG_07272	Aspartokinase. (544 aa)
	CHGG_07153	Aminotran_1_2 domain-containing protein. (618 aa)
	CHGG_07077	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (806 aa)
	CHGG_05216	MFS domain-containing protein. (533 aa)
	CHGG_05210	Uncharacterized protein. (308 aa)
	CHGG_05070	Uncharacterized protein. (447 aa)
	CHGG_04896	Uncharacterized protein. (439 aa)
	CHGG_04769	Uncharacterized protein. (546 aa)
	CHGG_04121	Uncharacterized protein. (371 aa)
	CHGG_06240	Semialdhyde_dh domain-containing protein. (362 aa)
	CHGG_06112	Uncharacterized protein. (184 aa)
	CHGG_05595	MFS domain-containing protein. (537 aa)
	CHGG_05442	Uncharacterized protein. (552 aa)
	CHGG_03686	Uncharacterized protein. (348 aa)
	CHGG_03595	Uncharacterized protein. (208 aa)
	CHGG_03464	Uncharacterized protein. (436 aa)
	CHGG_03423	Uncharacterized protein. (254 aa)
	CHGG_02542	Uncharacterized protein. (448 aa)
	CHGG_01611	Aminotran_1_2 domain-containing protein. (488 aa)
	CHGG_01573	Uncharacterized protein. (219 aa)
	CHGG_01425	Ppx-GppA domain-containing protein. (602 aa)
	CHGG_01353	Iso_dh domain-containing protein. (357 aa)
	CHGG_01290	Carrier domain-containing protein. (1173 aa)
	CHGG_01254	MFS domain-containing protein. (517 aa)
	CHGG_01218	MFS domain-containing protein. (482 aa)
	CHGG_00862	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (375 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00862	CHGG_01290	Q2HFZ2	Q2HER4	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Carrier domain-containing protein.	0.694
CHGG_00862	CHGG_01353	Q2HFZ2	Q2HEK1	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Iso_dh domain-containing protein.	0.608
CHGG_00862	CHGG_02542	Q2HFZ2	Q2HB62	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Uncharacterized protein.	0.846
CHGG_00862	CHGG_04121	Q2HFZ2	Q2H275	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Uncharacterized protein.	0.409
CHGG_00862	CHGG_06240	Q2HFZ2	Q2H525	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Semialdhyde_dh domain-containing protein.	0.507
CHGG_00862	CHGG_07330	Q2HFZ2	Q2GXH4	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Uncharacterized protein.	0.460
CHGG_00862	CHGG_08832	Q2HFZ2	Q2GT72	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Uncharacterized protein.	0.409
CHGG_00862	CHGG_09403	Q2HFZ2	Q2GRK1	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Uncharacterized protein.	0.826
CHGG_00862	LYS4	Q2HFZ2	Q2GN26	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.	0.460
CHGG_01290	CHGG_00862	Q2HER4	Q2HFZ2	Carrier domain-containing protein.	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	0.694
CHGG_01290	CHGG_01611	Q2HER4	Q2HDU3	Carrier domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.585
CHGG_01290	CHGG_02542	Q2HER4	Q2HB62	Carrier domain-containing protein.	Uncharacterized protein.	0.711
CHGG_01290	CHGG_03686	Q2HER4	Q2H7W8	Carrier domain-containing protein.	Uncharacterized protein.	0.585
CHGG_01290	CHGG_07077	Q2HER4	Q2GY77	Carrier domain-containing protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.414
CHGG_01290	CHGG_07153	Q2HER4	Q2GY01	Carrier domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.411
CHGG_01290	CHGG_09403	Q2HER4	Q2GRK1	Carrier domain-containing protein.	Uncharacterized protein.	0.711
CHGG_01353	CHGG_00862	Q2HEK1	Q2HFZ2	Iso_dh domain-containing protein.	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	0.608
CHGG_01353	CHGG_01573	Q2HEK1	Q2HDY1	Iso_dh domain-containing protein.	Uncharacterized protein.	0.599
CHGG_01353	CHGG_01611	Q2HEK1	Q2HDU3	Iso_dh domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.576
CHGG_01353	CHGG_02542	Q2HEK1	Q2HB62	Iso_dh domain-containing protein.	Uncharacterized protein.	0.667