78 items (Chaetomium globosum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BNA5-1	Kynureninase 1; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (509 aa)
	CHGG_00014	Uncharacterized protein. (486 aa)
	CHGG_00017	Isochorismatase domain-containing protein. (192 aa)
	CHGG_00062	Aldedh domain-containing protein. (376 aa)
	CHGG_00138	Uncharacterized protein. (471 aa)
	CHGG_00261	Uncharacterized protein; Belongs to the cytochrome P450 family. (468 aa)
	CHGG_00427	Dihydrolipoyl dehydrogenase. (498 aa)
	CHGG_00451	AAA domain-containing protein; Belongs to the AAA ATPase family. (834 aa)
	CHGG_00469	Lipoyl-binding domain-containing protein. (425 aa)
	CHGG_00607	Uncharacterized protein. (151 aa)
	CHGG_01122	Uncharacterized protein. (159 aa)
	CHGG_01233	Amino_oxidase domain-containing protein. (694 aa)
	CHGG_01279	Uncharacterized protein. (159 aa)
	CHGG_01280	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (522 aa)
	CHGG_01281	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (929 aa)
	CHGG_01390	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	CHGG_01611	Aminotran_1_2 domain-containing protein. (488 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (186 aa)
	CHGG_01981	Uncharacterized protein. (250 aa)
	CHGG_02069	Uncharacterized protein; Belongs to the cytochrome P450 family. (513 aa)
	CHGG_02312	Uncharacterized protein; Belongs to the cytochrome P450 family. (531 aa)
	CHGG_02821	Uncharacterized protein. (527 aa)
	CHGG_02906	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	CHGG_02976	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (705 aa)
	CHGG_03060	Uncharacterized protein. (210 aa)
	CHGG_03495	Amidase domain-containing protein. (532 aa)
	CHGG_03564	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (737 aa)
	CHGG_03593	Zn(2)-C6 fungal-type domain-containing protein. (772 aa)
	CHGG_03625	Uncharacterized protein. (262 aa)
	CHGG_03669	Uncharacterized protein. (559 aa)
	CHGG_03686	Uncharacterized protein. (348 aa)
	katG	Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. (749 aa)
	CHGG_05402	Uncharacterized protein. (144 aa)
	BNA5-2	Kynureninase 2; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (539 aa)
	CHGG_05496	Tr-type G domain-containing protein. (523 aa)
	CHGG_05689	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
	CHGG_06153	AB hydrolase-1 domain-containing protein. (491 aa)
	CHGG_06513	Amidase domain-containing protein. (559 aa)
	CHGG_06670	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (185 aa)
	CHGG_03793	Aminotran_1_2 domain-containing protein. (445 aa)
	CHGG_03838	Uncharacterized protein. (264 aa)
	CHGG_03996	Catalase domain-containing protein. (486 aa)
	CHGG_04063	Uncharacterized protein; Belongs to the cytochrome P450 family. (484 aa)
	CHGG_04527	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
	CHGG_04764	Uncharacterized protein. (506 aa)
	CHGG_04812	N-acetyltransferase domain-containing protein. (206 aa)
	CHGG_05242	Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
	CHGG_05254	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1064 aa)
	CHGG_07153	Aminotran_1_2 domain-containing protein. (618 aa)
	CHGG_07681	Uncharacterized protein; Belongs to the cytochrome P450 family. (467 aa)
	CHGG_08077	Aldehyde dehydrogenase. (472 aa)
	CHGG_08095	Aminotran_1_2 domain-containing protein. (425 aa)
	CHGG_08139	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	CHGG_08413	Uncharacterized protein. (210 aa)
	CHGG_08472	Uncharacterized protein. (509 aa)
	CHGG_08527	Amidase domain-containing protein. (368 aa)
	CHGG_08917	Uncharacterized protein. (320 aa)
	CHGG_09017	ANK_REP_REGION domain-containing protein. (2188 aa)
	CHGG_09072	Uncharacterized protein. (549 aa)
	CHGG_09097	Fungal_trans domain-containing protein. (770 aa)
	CHGG_09312	Uncharacterized protein. (197 aa)
	CHGG_09518	CN hydrolase domain-containing protein. (341 aa)
	CHGG_09530	Uncharacterized protein. (121 aa)
	CHGG_09532	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (484 aa)
	CHGG_09533	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (430 aa)
	CHGG_09562	Zn(2)-C6 fungal-type domain-containing protein. (1089 aa)
	CHGG_09606	Uncharacterized protein. (421 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (479 aa)
	CHGG_09923	Amino_oxidase domain-containing protein. (632 aa)
	CHGG_09937	CN hydrolase domain-containing protein. (336 aa)
	CHGG_10054	Uncharacterized protein. (346 aa)
	CHGG_10090	FAD_binding_3 domain-containing protein. (474 aa)
	CHGG_10448	Uncharacterized protein. (660 aa)
	CHGG_10511	CN hydrolase domain-containing protein. (439 aa)
	CHGG_10609	Amidase domain-containing protein. (672 aa)
	CHGG_10655	Uncharacterized protein. (776 aa)
	CHGG_10876	Amidase domain-containing protein. (500 aa)
	CHGG_10882	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (278 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA4	Q2HD63	Q2GQG8	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.846
BNA1	BNA5-1	Q2HD63	Q2H9P7	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase 1; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.944
BNA1	BNA5-2	Q2HD63	Q2H7G2	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase 2; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.946
BNA1	CHGG_01281	Q2HD63	Q2HES3	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.934
BNA1	CHGG_02976	Q2HD63	Q2H9X8	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.	0.818
BNA1	CHGG_03564	Q2HD63	Q2H890	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.560
BNA1	CHGG_03996	Q2HD63	Q2H2K0	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase domain-containing protein.	0.560
BNA1	CHGG_05402	Q2HD63	Q2H7G3	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.497
BNA1	CHGG_08472	Q2HD63	Q2GU82	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.497
BNA1	CHGG_09533	Q2HD63	Q2GR71	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.600
BNA1	CHGG_10448	Q2HD63	Q2GNK6	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.443
BNA1	CHGG_10882	Q2HD63	Q2GMC2	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.791
BNA1	katG	Q2HD63	Q2H7U1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.	0.807
BNA4	BNA1	Q2GQG8	Q2HD63	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.846
BNA4	BNA5-1	Q2GQG8	Q2H9P7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase 1; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.965
BNA4	BNA5-2	Q2GQG8	Q2H7G2	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase 2; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.958
BNA4	CHGG_01281	Q2GQG8	Q2HES3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.	0.543
BNA4	CHGG_01611	Q2GQG8	Q2HDU3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.467
BNA4	CHGG_03686	Q2GQG8	Q2H7W8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.467
BNA4	CHGG_03793	Q2GQG8	Q2H353	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.467