(66 nodes) Phagosome network (Chaetomium globosum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHGG_06538	FAD-binding FR-type domain-containing protein. (631 aa)
	CHGG_06527	FAD-binding FR-type domain-containing protein. (908 aa)
	CHGG_06474	Uncharacterized protein. (230 aa)
	CHGG_06444	RAS-related protein. (205 aa)
	CHGG_06424	Phosphatidylinositol 3-kinase VPS34. (890 aa)
	CHGG_06372	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (163 aa)
	CHGG_06014	NAD_binding_6 domain-containing protein. (392 aa)
	CHGG_05673	Uncharacterized protein. (204 aa)
	CHGG_05601	zf-Tim10_DDP domain-containing protein. (89 aa)
	CHGG_05590	Coronin; Belongs to the WD repeat coronin family. (612 aa)
	CHGG_05552	TPR_REGION domain-containing protein. (518 aa)
	CHGG_03673	Uncharacterized protein. (1250 aa)
	CHGG_03667	FAD-binding FR-type domain-containing protein. (635 aa)
	CHGG_03417	Uncharacterized protein. (376 aa)
	CHGG_03002	FAD-binding FR-type domain-containing protein. (595 aa)
	CHGG_02922	PH domain-containing protein. (1355 aa)
	CHGG_02797	V-ATPase_H_C domain-containing protein. (221 aa)
	CHGG_02796	Uncharacterized protein. (219 aa)
	CHGG_02654	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
	CHGG_02550	Uncharacterized protein. (205 aa)
	CHGG_02323	Ferric oxidoreductase domain-containing protein. (513 aa)
	CHGG_02318	Uncharacterized protein. (473 aa)
	CHGG_01959	Uncharacterized protein. (201 aa)
	CHGG_01825	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (115 aa)
	CHGG_01811	WD_REPEATS_REGION domain-containing protein. (663 aa)
	CHGG_01799	Uncharacterized protein. (97 aa)
	CHGG_01723	FAD-binding FR-type domain-containing protein. (553 aa)
	CHGG_01680	Uncharacterized protein. (2422 aa)
	CHGG_01486	Uncharacterized protein. (571 aa)
	CHGG_01342	Uncharacterized protein. (516 aa)
	CHGG_01168	Uncharacterized protein. (267 aa)
	CHGG_00734	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (200 aa)
	CHGG_00403	F-box domain-containing protein. (626 aa)
	CHGG_00172	Ferric oxidoreductase domain-containing protein. (772 aa)
	CHGG_00093	CFEM domain-containing protein. (412 aa)
	CHGG_10539	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (451 aa)
	CHGG_10169	Uncharacterized protein. (395 aa)
	CHGG_09735	Tr-type G domain-containing protein. (971 aa)
	CHGG_09662	FAD-binding FR-type domain-containing protein. (610 aa)
	CHGG_09609	FAD-binding FR-type domain-containing protein. (583 aa)
	VPS27	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (737 aa)
	CHGG_09039	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (375 aa)
	CHGG_08683	FAD-binding FR-type domain-containing protein. (611 aa)
	CHGG_08506	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (104 aa)
	CHGG_08421	Uncharacterized protein. (347 aa)
	CHGG_08178	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (863 aa)
	CHGG_08127	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (347 aa)
	CHGG_08099	Uncharacterized protein. (757 aa)
	CHGG_07772	Uncharacterized protein; Belongs to the synaptobrevin family. (215 aa)
	CHGG_07700	ATP-synt_ab domain-containing protein. (255 aa)
	CHGG_07575	Protein transport protein SEC61 alpha subunit. (476 aa)
	CHGG_07197	Uncharacterized protein. (73 aa)
	CHGG_07175	Uncharacterized protein. (664 aa)
	CHGG_05038	Uncharacterized protein. (354 aa)
	CHGG_04880	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
	CHGG_04876	Ferric oxidoreductase domain-containing protein. (714 aa)
	CHGG_04874	Uncharacterized protein. (624 aa)
	CHGG_04768	Uncharacterized protein. (216 aa)
	CHGG_04705	Uncharacterized protein. (299 aa)
	CHGG_04704	Uncharacterized protein. (75 aa)
	CHGG_04588	Vacuolar ATP synthase subunit D. (244 aa)
	CHGG_04501	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (202 aa)
	CHGG_04431	Uncharacterized protein. (303 aa)
	RRP3	ATP-dependent rRNA helicase RRP3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA. (493 aa)
	CHGG_03978	Dynein heavy chain. (2358 aa)
	CHGG_06720	Uncharacterized protein. (539 aa)

Your Current Organism:

Chaetomium globosum

NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHGG_00093	CHGG_00734	Q2HI61	Q2HGC0	CFEM domain-containing protein.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.440
CHGG_00093	CHGG_02654	Q2HI61	Q2HAV0	CFEM domain-containing protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.582
CHGG_00093	CHGG_04431	Q2HI61	Q2H1B5	CFEM domain-containing protein.	Uncharacterized protein.	0.444
CHGG_00093	CHGG_04501	Q2HI61	Q2H145	CFEM domain-containing protein.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.670
CHGG_00093	CHGG_04588	Q2HI61	Q2H0V8	CFEM domain-containing protein.	Vacuolar ATP synthase subunit D.	0.487
CHGG_00093	CHGG_04880	Q2HI61	Q2H016	CFEM domain-containing protein.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.485
CHGG_00093	CHGG_06372	Q2HI61	Q2H4P3	CFEM domain-containing protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.464
CHGG_00093	CHGG_06474	Q2HI61	Q2H4E1	CFEM domain-containing protein.	Uncharacterized protein.	0.487
CHGG_00093	CHGG_07700	Q2HI61	Q2GWF4	CFEM domain-containing protein.	ATP-synt_ab domain-containing protein.	0.637
CHGG_00093	CHGG_08127	Q2HI61	Q2GV77	CFEM domain-containing protein.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.	0.676
CHGG_00093	CHGG_08178	Q2HI61	Q2GV26	CFEM domain-containing protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.727
CHGG_00093	CHGG_08506	Q2HI61	Q2GU48	CFEM domain-containing protein.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.480
CHGG_00093	CHGG_10169	Q2HI61	Q2GPD5	CFEM domain-containing protein.	Uncharacterized protein.	0.449
CHGG_00734	CHGG_00093	Q2HGC0	Q2HI61	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	CFEM domain-containing protein.	0.440
CHGG_00734	CHGG_02318	Q2HGC0	Q2HBT6	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.917
CHGG_00734	CHGG_02654	Q2HGC0	Q2HAV0	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
CHGG_00734	CHGG_02796	Q2HGC0	Q2HAF8	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.987
CHGG_00734	CHGG_02797	Q2HGC0	Q2HAF7	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-ATPase_H_C domain-containing protein.	0.987
CHGG_00734	CHGG_03673	Q2HGC0	Q2H7Y1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.915
CHGG_00734	CHGG_04501	Q2HGC0	Q2H145	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.998