Your Input: | |
| | CLUG_00905 | Protein kinase domain-containing protein. (570 aa) |
| | CLUG_05823 | OB domain-containing protein. (294 aa) |
| | CLUG_05822 | Uncharacterized protein. (1704 aa) |
| | CLUG_05815 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) |
| | CLUG_05785 | Uncharacterized protein. (285 aa) |
| | CLUG_05772 | DNA_binding_1 domain-containing protein. (119 aa) |
| | CLUG_05897 | Uncharacterized protein. (102 aa) |
| | CLUG_05895 | Zf-primase domain-containing protein. (551 aa) |
| | CLUG_05879 | N-acetyltransferase domain-containing protein. (233 aa) |
| | CLUG_05739 | Uncharacterized protein. (332 aa) |
| | CLUG_05729 | Uncharacterized protein. (784 aa) |
| | CLUG_05728 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2985 aa) |
| | CLUG_05723 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (583 aa) |
| | CLUG_05714 | AAA domain-containing protein. (339 aa) |
| | CLUG_05651 | SER_THR_PHOSPHATASE domain-containing protein. (116 aa) |
| | CLUG_05647 | DNA helicase; Belongs to the MCM family. (916 aa) |
| | CLUG_05578 | AP_endonuc_2 domain-containing protein. (364 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (376 aa) |
| | CLUG_05545 | Uncharacterized protein. (409 aa) |
| | CLUG_05506 | Uncharacterized protein. (907 aa) |
| | CLUG_05504 | DNA polymerase. (1431 aa) |
| | CLUG_05497 | Uncharacterized protein. (1108 aa) |
| | CLUG_05482 | H2TH domain-containing protein. (346 aa) |
| | CLUG_05382 | Chromatin modification-related protein. (250 aa) |
| | CLUG_05341 | Cell division control protein 28. (300 aa) |
| | CLUG_05398 | Uncharacterized protein. (656 aa) |
| | CLUG_05299 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (1002 aa) |
| | CLUG_05076 | Helicase ATP-binding domain-containing protein. (439 aa) |
| | CLUG_05075 | HELICc2 domain-containing protein. (315 aa) |
| | CLUG_05065 | Uncharacterized protein. (404 aa) |
| | CLUG_05063 | Uncharacterized protein. (231 aa) |
| | CLUG_05036 | BSD domain-containing protein. (640 aa) |
| | CLUG_05202 | Uncharacterized protein. (846 aa) |
| | CLUG_05201 | Ada_Zn_binding domain-containing protein. (198 aa) |
| | CLUG_05138 | Ada_Zn_binding domain-containing protein. (434 aa) |
| | CLUG_05136 | UmuC domain-containing protein. (748 aa) |
| | CLUG_05124 | RMI1_N domain-containing protein. (176 aa) |
| | CLUG_05123 | ERCC4 domain-containing protein. (1112 aa) |
| | CLUG_04905 | MRC1 domain-containing protein. (1119 aa) |
| | CLUG_04873 | Uncharacterized protein. (793 aa) |
| | CLUG_04866 | Uncharacterized protein. (885 aa) |
| | CLUG_04833 | Uncharacterized protein. (154 aa) |
| | CLUG_04832 | Uncharacterized protein. (277 aa) |
| | CLUG_04830 | Uncharacterized protein. (643 aa) |
| | CLUG_04826 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1320 aa) |
| | CLUG_04810 | RING-type domain-containing protein. (324 aa) |
| | CLUG_04807 | Uncharacterized protein. (620 aa) |
| | CLUG_04799 | Deacetylase sirtuin-type domain-containing protein. (462 aa) |
| | CLUG_04708 | Uncharacterized protein. (114 aa) |
| | CLUG_04707 | WD_REPEATS_REGION domain-containing protein. (1036 aa) |
| | CLUG_04680 | Fungal_trans domain-containing protein. (905 aa) |
| | CLUG_04662 | Fe2OG dioxygenase domain-containing protein. (416 aa) |
| | CLUG_04637 | Uncharacterized protein. (569 aa) |
| | CLUG_04636 | Uncharacterized protein. (745 aa) |
| | CLUG_04612 | Uncharacterized protein. (268 aa) |
| | CLUG_04560 | Uncharacterized protein. (1563 aa) |
| | CLUG_04517 | Uncharacterized protein. (1606 aa) |
| | CLUG_04445 | Uncharacterized protein. (819 aa) |
| | CLUG_04428 | Plus3 domain-containing protein. (550 aa) |
| | CLUG_04376 | AAA domain-containing protein. (386 aa) |
| | CLUG_04307 | SP-RING-type domain-containing protein. (273 aa) |
| | CLUG_04237 | HMG box domain-containing protein. (195 aa) |
| | CLUG_04218 | Uncharacterized protein. (1269 aa) |
| | CLUG_04196 | UDG domain-containing protein. (427 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (759 aa) |
| | CLUG_04126 | Uncharacterized protein. (1266 aa) |
| | CLUG_04113 | DNA helicase; Belongs to the MCM family. (831 aa) |
| | CLUG_04041 | HSA domain-containing protein. (1000 aa) |
| | CLUG_03995 | Enhancer of polycomb-like protein. (967 aa) |
| | RRM3 | ATP-dependent DNA helicase RRM3; 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein- DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G- quadruplex (G4) unwindi [...] (640 aa) |
| | CLUG_03957 | zf-C2HE domain-containing protein. (232 aa) |
| | CLUG_03934 | Uncharacterized protein. (677 aa) |
| | CLUG_03933 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (333 aa) |
| | CLUG_03929 | Uncharacterized protein. (312 aa) |
| | CLUG_03914 | Uncharacterized protein. (475 aa) |
| | CLUG_03896 | Uncharacterized protein. (142 aa) |
| | CLUG_03859 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (718 aa) |
| | CLUG_03822 | AAA_15 domain-containing protein. (425 aa) |
| | CLUG_03821 | Uncharacterized protein. (559 aa) |
| | CLUG_03809 | Casein kinase I; Belongs to the protein kinase superfamily. (449 aa) |
| | CLUG_03764 | DNA helicase; Belongs to the MCM family. (934 aa) |
| | CLUG_03761 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa) |
| | CLUG_03759 | Uncharacterized protein. (871 aa) |
| | CLUG_03728 | DNA polymerase. (1533 aa) |
| | CLUG_03712 | AAA domain-containing protein; Belongs to the AAA ATPase family. (427 aa) |
| | CLUG_03791 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2876 aa) |
| | CLUG_03697 | ERCC4 domain-containing protein. (515 aa) |
| | CLUG_03604 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (826 aa) |
| | CLUG_03580 | Sister chromatid cohesion protein. (1525 aa) |
| | CLUG_03532 | Rad60-SLD domain-containing protein. (386 aa) |
| | CLUG_03520 | Uncharacterized protein. (490 aa) |
| | CLUG_03517 | Uncharacterized protein. (1056 aa) |
| | CLUG_03507 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (288 aa) |
| | CLUG_03491 | Ku domain-containing protein. (705 aa) |
| | CLUG_03480 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (235 aa) |
| | CLUG_03478 | Uncharacterized protein. (519 aa) |
| | CLUG_03414 | Uncharacterized protein. (613 aa) |
| | CLUG_03348 | Nudix hydrolase domain-containing protein. (304 aa) |
| | CLUG_03289 | Uncharacterized protein. (810 aa) |
| | CLUG_03276 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (459 aa) |
| | CLUG_03241 | Actin. (360 aa) |
| | CLUG_03224 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (100 aa) |
| | CLUG_02622 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2384 aa) |
| | CLUG_02568 | Uncharacterized protein. (211 aa) |
| | CLUG_02530 | AAA domain-containing protein; Belongs to the AAA ATPase family. (399 aa) |
| | CLUG_02492 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | CLUG_02460 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (511 aa) |
| | CLUG_02422 | MRG domain-containing protein. (331 aa) |
| | CLUG_02411 | ENDO3c domain-containing protein. (327 aa) |
| | CLUG_02405 | Uncharacterized protein. (467 aa) |
| | CLUG_02401 | Structural maintenance of chromosomes protein. (1193 aa) |
| | CLUG_02400 | Uncharacterized protein. (748 aa) |
| | CLUG_02390 | Uncharacterized protein. (270 aa) |
| | CLUG_02337 | Structural maintenance of chromosomes protein. (1190 aa) |
| | CLUG_02334 | Uncharacterized protein. (340 aa) |
| | CLUG_03182 | Uncharacterized protein. (655 aa) |
| | CLUG_03181 | Uncharacterized protein. (375 aa) |
| | CLUG_03172 | Uncharacterized protein. (1284 aa) |
| | CLUG_03110 | Uncharacterized protein. (600 aa) |
| | CLUG_03029 | DNA helicase; Belongs to the MCM family. (859 aa) |
| | CLUG_02998 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa) |
| | CLUG_02983 | HSM3_C domain-containing protein. (545 aa) |
| | CLUG_02949 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (495 aa) |
| | CLUG_02932 | Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (806 aa) |
| | CLUG_02869 | Uncharacterized protein. (233 aa) |
| | CLUG_02865 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (345 aa) |
| | CLUG_02808 | Uncharacterized protein. (878 aa) |
| | CLUG_02807 | HORMA domain-containing protein. (221 aa) |
| | CLUG_02790 | Uncharacterized protein. (1009 aa) |
| | CLUG_02722 | DNA_binding_1 domain-containing protein. (185 aa) |
| | CLUG_02700 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (989 aa) |
| | CLUG_02261 | Uncharacterized protein. (2117 aa) |
| | CLUG_02253 | Uncharacterized protein. (188 aa) |
| | CLUG_02252 | Uncharacterized protein. (1063 aa) |
| | CLUG_02228 | AAA_23 domain-containing protein. (1277 aa) |
| | CLUG_02212 | Uncharacterized protein. (729 aa) |
| | CLUG_02158 | AAA domain-containing protein. (768 aa) |
| | CLUG_02152 | ENDO3c domain-containing protein. (494 aa) |
| | CLUG_02150 | Uncharacterized protein. (663 aa) |
| | CLUG_02129 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | DEF1 | RNA polymerase II degradation factor 1; RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation (By similarity); Belongs to the DEF1 family. (671 aa) |
| | CLUG_02117 | Uncharacterized protein. (1138 aa) |
| | CLUG_02066 | MutL_C domain-containing protein. (610 aa) |
| | CLUG_02058 | CDT1_C domain-containing protein. (299 aa) |
| | CLUG_02050 | Uncharacterized protein. (1186 aa) |
| | CLUG_01852 | Uncharacterized protein. (1019 aa) |
| | CLUG_01809 | zf-RING-like domain-containing protein. (241 aa) |
| | CLUG_01772 | DNA_mis_repair domain-containing protein. (711 aa) |
| | CLUG_01771 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (343 aa) |
| | CLUG_01705 | DRMBL domain-containing protein. (623 aa) |
| | CLUG_01630 | DNA helicase; Belongs to the MCM family. (728 aa) |
| | CLUG_01618 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (737 aa) |
| | CLUG_01599 | Uncharacterized protein. (242 aa) |
| | CLUG_01591 | Uncharacterized protein. (154 aa) |
| | CLUG_01590 | ERCC4 domain-containing protein. (212 aa) |
| | CLUG_01589 | ERCC4 domain-containing protein. (226 aa) |
| | CLUG_01569 | Uncharacterized protein. (435 aa) |
| | CLUG_01548 | Uncharacterized protein. (960 aa) |
| | CLUG_01541 | Uncharacterized protein. (409 aa) |
| | CLUG_01511 | ATP-dependent DNA helicase; Belongs to the helicase family. (221 aa) |
| | CLUG_01510 | Uncharacterized protein. (167 aa) |
| | CLUG_01476 | Uncharacterized protein. (321 aa) |
| | CLUG_01350 | DNA ligase. (780 aa) |
| | CLUG_01321 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1124 aa) |
| | NTG1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (384 aa) |
| | CLUG_01265 | TIMELESS domain-containing protein. (1245 aa) |
| | UNG1 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (375 aa) |
| | CLUG_01248 | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (1117 aa) |
| | CLUG_01245 | Uncharacterized protein. (237 aa) |
| | CLUG_01172 | Rep_fac_C domain-containing protein. (256 aa) |
| | CLUG_01075 | Replication factor C subunit 1. (876 aa) |
| | CLUG_01069 | Uncharacterized protein. (1061 aa) |
| | CLUG_01056 | Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family. (961 aa) |
| | CLUG_01054 | Uncharacterized protein. (962 aa) |
| | CLUG_01040 | Uncharacterized protein. (1616 aa) |
| | CLUG_01039 | SANT domain-containing protein. (623 aa) |
| | CLUG_00998 | XPA_C domain-containing protein. (230 aa) |
| | CLUG_00981 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (427 aa) |
| | CLUG_00901 | Uncharacterized protein. (1162 aa) |
| | CLUG_00847 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa) |
| | CLUG_00838 | AAA domain-containing protein. (784 aa) |
| | CLUG_00806 | MAGE domain-containing protein. (294 aa) |
| | CLUG_00798 | Uncharacterized protein. (886 aa) |
| | CLUG_00788 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa) |
| | CLUG_00766 | DNA_pol_E_B domain-containing protein. (670 aa) |
| | CLUG_00760 | Uncharacterized protein. (1489 aa) |
| | CLUG_00744 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (946 aa) |
| | CLUG_00743 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1337 aa) |
| | CLUG_00709 | Uncharacterized protein. (1970 aa) |
| | CLUG_00559 | Uncharacterized protein. (729 aa) |
| | CLUG_00558 | Uncharacterized protein. (106 aa) |
| | CLUG_00547 | Uncharacterized protein. (469 aa) |
| | CLUG_00526 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (157 aa) |
| | CLUG_00514 | Rad51 domain-containing protein. (315 aa) |
| | CLUG_00513 | RECA_2 domain-containing protein. (211 aa) |
| | CLUG_00462 | Uncharacterized protein. (364 aa) |
| | CLUG_00441 | Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (410 aa) |
| | CLUG_00368 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (488 aa) |
| | CLUG_00367 | Uncharacterized protein. (1029 aa) |
| | CLUG_00336 | Helicase C-terminal domain-containing protein. (187 aa) |
| | CLUG_00335 | Uncharacterized protein. (964 aa) |
| | CLUG_00249 | Uncharacterized protein. (451 aa) |
| | CLUG_00213 | U-box domain-containing protein. (473 aa) |
| | CLUG_00201 | Uncharacterized protein. (1408 aa) |
| | CLUG_00138 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (538 aa) |
| | CLUG_00135 | SAC3 domain-containing protein. (1358 aa) |
| | CLUG_00127 | Uncharacterized protein. (266 aa) |
| | CLUG_00085 | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. (240 aa) |
| | CLUG_00068 | Uncharacterized protein. (416 aa) |
| | CLUG_00007 | Ku domain-containing protein. (440 aa) |
| | CLUG_00002 | Uncharacterized protein; Belongs to the actin family. (474 aa) |
