STRINGSTRING
CLUG_01406 CLUG_01406 CLUG_00085 CLUG_00085 CLUG_00107 CLUG_00107 CLUG_00192 CLUG_00192 CLUG_00298 CLUG_00298 CLUG_00334 CLUG_00334 CLUG_00367 CLUG_00367 CLUG_00441 CLUG_00441 CLUG_00465 CLUG_00465 CLUG_00486 CLUG_00486 CLUG_00609 CLUG_00609 CLUG_00615 CLUG_00615 CLUG_00704 CLUG_00704 CLUG_00745 CLUG_00745 CLUG_00756 CLUG_00756 CLUG_00841 CLUG_00841 CLUG_00901 CLUG_00901 CLUG_00953 CLUG_00953 CLUG_01069 CLUG_01069 CLUG_01237 CLUG_01237 CLUG_01277 CLUG_01277 CLUG_01334 CLUG_01334 CLUG_03772 CLUG_03772 CLUG_03775 CLUG_03775 CLUG_03798 CLUG_03798 CLUG_03799 CLUG_03799 CLUG_03800 CLUG_03800 CLUG_03859 CLUG_03859 CLUG_03884 CLUG_03884 CLUG_03939 CLUG_03939 CLUG_04113 CLUG_04113 MCM7 MCM7 CLUG_04550 CLUG_04550 CLUG_04582 CLUG_04582 CLUG_04620 CLUG_04620 CLUG_04773 CLUG_04773 CLUG_04783 CLUG_04783 CLUG_04799 CLUG_04799 CLUG_04834 CLUG_04834 CLUG_04905 CLUG_04905 CLUG_05163 CLUG_05163 CLUG_04992 CLUG_04992 CLUG_05524 CLUG_05524 CLUG_05895 CLUG_05895 CLUG_05920 CLUG_05920 CLUG_05921 CLUG_05921 CLUG_05931 CLUG_05931 CLUG_01459 CLUG_01459 CLUG_01532 CLUG_01532 CLUG_01630 CLUG_01630 CLUG_01659 CLUG_01659 CLUG_01726 CLUG_01726 CLUG_01808 CLUG_01808 CLUG_02117 CLUG_02117 CLUG_02129 CLUG_02129 CLUG_02700 CLUG_02700 CLUG_02769 CLUG_02769 CLUG_02881 CLUG_02881 CLUG_02967 CLUG_02967 CLUG_03161 CLUG_03161 CLUG_02382 CLUG_02382 CLUG_02493 CLUG_02493 CLUG_03299 CLUG_03299 CLUG_03436 CLUG_03436 CLUG_03515 CLUG_03515 CLUG_03532 CLUG_03532 CLUG_03734 CLUG_03734
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLUG_01406Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CLUG_00085Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. (240 aa)
CLUG_00107CBFD_NFYB_HMF domain-containing protein. (229 aa)
CLUG_00192USP domain-containing protein; Belongs to the peptidase C19 family. (650 aa)
CLUG_00298Rtt106 domain-containing protein. (511 aa)
CLUG_00334Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (319 aa)
CLUG_00367Uncharacterized protein. (1029 aa)
CLUG_00441Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (410 aa)
CLUG_00465RFX-type winged-helix domain-containing protein. (617 aa)
CLUG_00486Uncharacterized protein. (330 aa)
CLUG_00609ANK_REP_REGION domain-containing protein. (1111 aa)
CLUG_00615Histone H2A; Belongs to the histone H2A family. (154 aa)
CLUG_00704SHNi-TPR domain-containing protein. (347 aa)
CLUG_00745Uncharacterized protein. (471 aa)
CLUG_00756ORC_WH_C domain-containing protein. (744 aa)
CLUG_00841AAA domain-containing protein. (967 aa)
CLUG_00901Uncharacterized protein. (1162 aa)
CLUG_00953FK506-binding protein. (425 aa)
CLUG_01069Uncharacterized protein. (1061 aa)
CLUG_01237Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (399 aa)
CLUG_01277Deacetylase sirtuin-type domain-containing protein. (522 aa)
CLUG_01334WD_REPEATS_REGION domain-containing protein. (437 aa)
CLUG_03772GATA-type domain-containing protein. (729 aa)
CLUG_03775Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (976 aa)
CLUG_03798WAC domain-containing protein. (569 aa)
CLUG_03799Uncharacterized protein. (339 aa)
CLUG_03800WSD domain-containing protein. (248 aa)
CLUG_03859Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (718 aa)
CLUG_03884PHD-type domain-containing protein. (389 aa)
CLUG_03939Uncharacterized protein. (369 aa)
CLUG_04113DNA helicase; Belongs to the MCM family. (831 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (759 aa)
CLUG_04550Checkpoint protein; Belongs to the HUS1 family. (320 aa)
CLUG_04582NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (366 aa)
CLUG_04620Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1163 aa)
CLUG_04773Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (249 aa)
CLUG_04783Uncharacterized protein. (274 aa)
CLUG_04799Deacetylase sirtuin-type domain-containing protein. (462 aa)
CLUG_04834Uncharacterized protein. (559 aa)
CLUG_04905MRC1 domain-containing protein. (1119 aa)
CLUG_05163AAA domain-containing protein. (788 aa)
CLUG_04992Uncharacterized protein. (662 aa)
CLUG_05524J domain-containing protein. (276 aa)
CLUG_05895Zf-primase domain-containing protein. (551 aa)
CLUG_05920Uncharacterized protein. (806 aa)
CLUG_05921Uncharacterized protein. (361 aa)
CLUG_05931Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1432 aa)
CLUG_01459DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (764 aa)
CLUG_01532WD_REPEATS_REGION domain-containing protein. (356 aa)
CLUG_01630DNA helicase; Belongs to the MCM family. (728 aa)
CLUG_01659Isochorismatase domain-containing protein. (242 aa)
CLUG_01726tRNA dimethylallyltransferase. (419 aa)
CLUG_01808B30.2/SPRY domain-containing protein. (286 aa)
CLUG_02117Uncharacterized protein. (1138 aa)
CLUG_02129Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
CLUG_02700DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (989 aa)
CLUG_02769Uncharacterized protein. (728 aa)
CLUG_02881RanBD1 domain-containing protein. (754 aa)
CLUG_02967Uncharacterized protein. (616 aa)
CLUG_03161Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (332 aa)
CLUG_02382Uncharacterized protein. (345 aa)
CLUG_02493Histone H2B; Belongs to the histone H2B family. (130 aa)
CLUG_03299WD_REPEATS_REGION domain-containing protein. (596 aa)
CLUG_03436Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (250 aa)
CLUG_03515Uncharacterized protein. (1841 aa)
CLUG_03532Rad60-SLD domain-containing protein. (386 aa)
CLUG_03734Uncharacterized protein. (150 aa)
Your Current Organism:
Clavispora lusitaniae
NCBI taxonomy Id: 306902
Other names: C. lusitaniae ATCC 42720, Candida lusitaniae ATCC 42720, Clavispora lusitaniae ATCC 42720
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