(8 nodes) Tricarboxylic acid cycle enzyme complex network (Clavispora lusitaniae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	CLUG_01495	Lipoyl-binding domain-containing protein. (436 aa)
	CLUG_01686	Dihydrolipoyl dehydrogenase. (504 aa)
	CLUG_02473	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (425 aa)
	CLUG_03520	Uncharacterized protein. (490 aa)
	CLUG_03602	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (324 aa)
	CLUG_04220	Transket_pyr domain-containing protein. (999 aa)
	CLUG_05795	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (364 aa)
	CLUG_05434	Iso_dh domain-containing protein. (194 aa)

Your Current Organism:

Clavispora lusitaniae

NCBI taxonomy Id: 306902
Other names: C. lusitaniae ATCC 42720, Candida lusitaniae ATCC 42720, Clavispora lusitaniae ATCC 42720

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLUG_01495	CLUG_01686	C4XZW3	C4Y0F4	Lipoyl-binding domain-containing protein.	Dihydrolipoyl dehydrogenase.	0.999
CLUG_01495	CLUG_02473	C4XZW3	C4Y4A1	Lipoyl-binding domain-containing protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.992
CLUG_01495	CLUG_03520	C4XZW3	C4Y5T6	Lipoyl-binding domain-containing protein.	Uncharacterized protein.	0.815
CLUG_01495	CLUG_03602	C4XZW3	C4Y618	Lipoyl-binding domain-containing protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.991
CLUG_01495	CLUG_04220	C4XZW3	C4Y7P2	Lipoyl-binding domain-containing protein.	Transket_pyr domain-containing protein.	0.999
CLUG_01495	CLUG_05434	C4XZW3	C4YAW9	Lipoyl-binding domain-containing protein.	Iso_dh domain-containing protein.	0.727
CLUG_01495	CLUG_05795	C4XZW3	C4YCF6	Lipoyl-binding domain-containing protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.740
CLUG_01686	CLUG_01495	C4Y0F4	C4XZW3	Dihydrolipoyl dehydrogenase.	Lipoyl-binding domain-containing protein.	0.999
CLUG_01686	CLUG_02473	C4Y0F4	C4Y4A1	Dihydrolipoyl dehydrogenase.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.959
CLUG_01686	CLUG_03520	C4Y0F4	C4Y5T6	Dihydrolipoyl dehydrogenase.	Uncharacterized protein.	0.863
CLUG_01686	CLUG_03602	C4Y0F4	C4Y618	Dihydrolipoyl dehydrogenase.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.884
CLUG_01686	CLUG_04220	C4Y0F4	C4Y7P2	Dihydrolipoyl dehydrogenase.	Transket_pyr domain-containing protein.	0.998
CLUG_01686	CLUG_05434	C4Y0F4	C4YAW9	Dihydrolipoyl dehydrogenase.	Iso_dh domain-containing protein.	0.805
CLUG_01686	CLUG_05795	C4Y0F4	C4YCF6	Dihydrolipoyl dehydrogenase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.780
CLUG_02473	CLUG_01495	C4Y4A1	C4XZW3	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Lipoyl-binding domain-containing protein.	0.992
CLUG_02473	CLUG_01686	C4Y4A1	C4Y0F4	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Dihydrolipoyl dehydrogenase.	0.959
CLUG_02473	CLUG_03520	C4Y4A1	C4Y5T6	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Uncharacterized protein.	0.766
CLUG_02473	CLUG_03602	C4Y4A1	C4Y618	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.999
CLUG_02473	CLUG_04220	C4Y4A1	C4Y7P2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Transket_pyr domain-containing protein.	0.993
CLUG_02473	CLUG_05434	C4Y4A1	C4YAW9	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Iso_dh domain-containing protein.	0.670