(5 nodes) PCI/PINT associated module, and Proteasome storage granule network (Oryzias melastigma)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	psmd11	Proteasome 26S subunit, non-ATPase 11b. (422 aa)
	usp14	Ubiquitin carboxyl-terminal hydrolase. (491 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	ENSOMEP00000019316	Proteasome 26S subunit, non-ATPase 3. (567 aa)
	psmd2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000019316	psmc1	ENSOMEP00000019316	ENSOMEP00000012724	Proteasome 26S subunit, non-ATPase 3.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.999
ENSOMEP00000019316	psmd11	ENSOMEP00000019316	ENSOMEP00000003166	Proteasome 26S subunit, non-ATPase 3.	Proteasome 26S subunit, non-ATPase 11b.	0.999
ENSOMEP00000019316	psmd2	ENSOMEP00000019316	ENSOMEP00000033421	Proteasome 26S subunit, non-ATPase 3.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
ENSOMEP00000019316	usp14	ENSOMEP00000019316	ENSOMEP00000007166	Proteasome 26S subunit, non-ATPase 3.	Ubiquitin carboxyl-terminal hydrolase.	0.999
psmc1	ENSOMEP00000019316	ENSOMEP00000012724	ENSOMEP00000019316	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 3.	0.999
psmc1	psmd11	ENSOMEP00000012724	ENSOMEP00000003166	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 11b.	0.999
psmc1	psmd2	ENSOMEP00000012724	ENSOMEP00000033421	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
psmc1	usp14	ENSOMEP00000012724	ENSOMEP00000007166	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Ubiquitin carboxyl-terminal hydrolase.	0.999
psmd11	ENSOMEP00000019316	ENSOMEP00000003166	ENSOMEP00000019316	Proteasome 26S subunit, non-ATPase 11b.	Proteasome 26S subunit, non-ATPase 3.	0.999
psmd11	psmc1	ENSOMEP00000003166	ENSOMEP00000012724	Proteasome 26S subunit, non-ATPase 11b.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.999
psmd11	psmd2	ENSOMEP00000003166	ENSOMEP00000033421	Proteasome 26S subunit, non-ATPase 11b.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
psmd11	usp14	ENSOMEP00000003166	ENSOMEP00000007166	Proteasome 26S subunit, non-ATPase 11b.	Ubiquitin carboxyl-terminal hydrolase.	0.999
psmd2	ENSOMEP00000019316	ENSOMEP00000033421	ENSOMEP00000019316	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Proteasome 26S subunit, non-ATPase 3.	0.999
psmd2	psmc1	ENSOMEP00000033421	ENSOMEP00000012724	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.999
psmd2	psmd11	ENSOMEP00000033421	ENSOMEP00000003166	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Proteasome 26S subunit, non-ATPase 11b.	0.999
psmd2	usp14	ENSOMEP00000033421	ENSOMEP00000007166	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Ubiquitin carboxyl-terminal hydrolase.	0.999
usp14	ENSOMEP00000019316	ENSOMEP00000007166	ENSOMEP00000019316	Ubiquitin carboxyl-terminal hydrolase.	Proteasome 26S subunit, non-ATPase 3.	0.999
usp14	psmc1	ENSOMEP00000007166	ENSOMEP00000012724	Ubiquitin carboxyl-terminal hydrolase.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.999
usp14	psmd11	ENSOMEP00000007166	ENSOMEP00000003166	Ubiquitin carboxyl-terminal hydrolase.	Proteasome 26S subunit, non-ATPase 11b.	0.999
usp14	psmd2	ENSOMEP00000007166	ENSOMEP00000033421	Ubiquitin carboxyl-terminal hydrolase.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999