(35 nodes) Mixed, incl. Fatty acid biosynthesis, and Palmitoyl hydrolase activity network (Oryzias melastigma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kiaa1107	Si:ch73-389b16.2. (1521 aa)
	lipc	Lipase, hepatic a. (494 aa)
	acacb	Acetyl-CoA carboxylase beta. (2423 aa)
	LOC112142411	AMP-binding domain-containing protein. (722 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (304 aa)
	ENSOMEP00000005634	Uncharacterized protein. (309 aa)
	ENSOMEP00000006185	Hydrolase_4 domain-containing protein. (323 aa)
	ENSOMEP00000006358	Monoglyceride lipase. (295 aa)
	LOC112157163	Acyl-CoA synthetase long chain family member 1a. (698 aa)
	LOC112148245	Acyl-CoA synthetase long chain family member 2. (711 aa)
	LOC112152828	Carnitine palmitoyltransferase 1B (muscle); Belongs to the carnitine/choline acetyltransferase family. (784 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (514 aa)
	cmbl	Carboxymethylenebutenolidase homolog (Pseudomonas). (245 aa)
	acsl4	Acyl-CoA synthetase long chain family member 4a. (676 aa)
	ENSOMEP00000012439	Coiled-coil domain containing 57. (2510 aa)
	lipg	Lipase, endothelial. (496 aa)
	mecr	Mitochondrial trans-2-enoyl-CoA reductase. (379 aa)
	LOC112152272	Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	acsl3	Uncharacterized protein. (719 aa)
	ENSOMEP00000017395	Si:ch73-95l15.5. (645 aa)
	ENSOMEP00000017437	Uncharacterized protein. (311 aa)
	ENSOMEP00000017532	Uncharacterized protein. (321 aa)
	LOC112136510	Uncharacterized protein. (289 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (732 aa)
	ENSOMEP00000018071	Uncharacterized protein. (234 aa)
	ENSOMEP00000020228	Uncharacterized protein. (140 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (526 aa)
	acsl5	Acyl-CoA synthetase long chain family member 5. (707 aa)
	acsbg2	Acyl-CoA synthetase bubblegum family member 2. (770 aa)
	ENSOMEP00000026411	Palmitoyl-protein thioesterase 2. (277 aa)
	LOC112146686	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (786 aa)
	LOC112148647	AMP-binding domain-containing protein. (717 aa)
	CEL-2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)
	LOC112154614	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (785 aa)
	LOC112147079	Acyl-CoA synthetase long chain family member 3b. (711 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSL1	CEL	ENSOMEP00000017825	ENSOMEP00000024095	Acyl-CoA synthetase long chain family member 1.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.858
ACSL1	CEL-2	ENSOMEP00000017825	ENSOMEP00000030670	Acyl-CoA synthetase long chain family member 1.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.858
ACSL1	ENSOMEP00000005634	ENSOMEP00000017825	ENSOMEP00000005634	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein.	0.796
ACSL1	ENSOMEP00000006185	ENSOMEP00000017825	ENSOMEP00000006185	Acyl-CoA synthetase long chain family member 1.	Hydrolase_4 domain-containing protein.	0.766
ACSL1	ENSOMEP00000006358	ENSOMEP00000017825	ENSOMEP00000006358	Acyl-CoA synthetase long chain family member 1.	Monoglyceride lipase.	0.766
ACSL1	ENSOMEP00000012439	ENSOMEP00000017825	ENSOMEP00000012439	Acyl-CoA synthetase long chain family member 1.	Coiled-coil domain containing 57.	0.909
ACSL1	ENSOMEP00000017395	ENSOMEP00000017825	ENSOMEP00000017395	Acyl-CoA synthetase long chain family member 1.	Si:ch73-95l15.5.	0.456
ACSL1	ENSOMEP00000017437	ENSOMEP00000017825	ENSOMEP00000017437	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein.	0.796
ACSL1	ENSOMEP00000017532	ENSOMEP00000017825	ENSOMEP00000017532	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein.	0.796
ACSL1	ENSOMEP00000026411	ENSOMEP00000017825	ENSOMEP00000026411	Acyl-CoA synthetase long chain family member 1.	Palmitoyl-protein thioesterase 2.	0.797
ACSL1	LOC112136510	ENSOMEP00000017825	ENSOMEP00000017793	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein.	0.796
ACSL1	LOC112142411	ENSOMEP00000017825	ENSOMEP00000003246	Acyl-CoA synthetase long chain family member 1.	AMP-binding domain-containing protein.	0.852
ACSL1	LOC112146686	ENSOMEP00000017825	ENSOMEP00000028150	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family.	0.867
ACSL1	LOC112147079	ENSOMEP00000017825	ENSOMEP00000035683	Acyl-CoA synthetase long chain family member 1.	Acyl-CoA synthetase long chain family member 3b.	0.883
ACSL1	LOC112148245	ENSOMEP00000017825	ENSOMEP00000007796	Acyl-CoA synthetase long chain family member 1.	Acyl-CoA synthetase long chain family member 2.	0.853
ACSL1	LOC112148647	ENSOMEP00000017825	ENSOMEP00000029325	Acyl-CoA synthetase long chain family member 1.	AMP-binding domain-containing protein.	0.868
ACSL1	LOC112152272	ENSOMEP00000017825	ENSOMEP00000017375	Acyl-CoA synthetase long chain family member 1.	Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family.	0.868
ACSL1	LOC112152828	ENSOMEP00000017825	ENSOMEP00000007910	Acyl-CoA synthetase long chain family member 1.	Carnitine palmitoyltransferase 1B (muscle); Belongs to the carnitine/choline acetyltransferase family.	0.872
ACSL1	LOC112154614	ENSOMEP00000017825	ENSOMEP00000032948	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family.	0.868
ACSL1	LOC112157163	ENSOMEP00000017825	ENSOMEP00000006381	Acyl-CoA synthetase long chain family member 1.	Acyl-CoA synthetase long chain family member 1a.	0.774