STRINGSTRING
ENSOMEP00000006056 ENSOMEP00000006056 LOC112136949 LOC112136949 LOC112136593 LOC112136593 ILK ILK ENSOMEP00000023058 ENSOMEP00000023058 LOC112148176 LOC112148176 ENSOMEP00000020557 ENSOMEP00000020557 cited1 cited1 tcf21 tcf21 LOC112142591 LOC112142591 wnt6 wnt6 ENSOMEP00000010252 ENSOMEP00000010252 gdnf gdnf wt1 wt1 LOC112152632 LOC112152632 fgf1 fgf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSOMEP00000006056Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (201 aa)
LOC112136949Transmembrane protein 59-like. (338 aa)
LOC112136593Mothers against decapentaplegic homolog. (536 aa)
ILKIntegrin linked kinase. (452 aa)
ENSOMEP00000023058Mothers against decapentaplegic homolog. (493 aa)
LOC112148176Mothers against decapentaplegic homolog. (510 aa)
ENSOMEP00000020557Catenin, beta interacting protein 1. (81 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (162 aa)
tcf21Transcription factor 21. (172 aa)
LOC112142591Uncharacterized protein. (452 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
ENSOMEP00000010252Growth regulating estrogen receptor binding 1. (1882 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (266 aa)
wt1WT1 transcription factor b. (419 aa)
LOC112152632WT1 transcription factor a. (438 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (268 aa)
Your Current Organism:
Oryzias melastigma
NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka
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