(9 nodes) Very-low-density lipoprotein particle network (Oryzias melastigma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112157799	Apolipoprotein Bb, tandem duplicate 2. (3796 aa)
	LOC112137180	Uncharacterized protein. (364 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (514 aa)
	LOC112150654	PLAT domain-containing protein. (510 aa)
	LOC112142808	Apolipoprotein Ba. (4400 aa)
	LOC112143596	Apolipoprotein Eb. (265 aa)
	apom	Uncharacterized protein. (191 aa)
	ENSOMEP00000004933	Vitellogenin domain-containing protein. (774 aa)
	LOC112137153	Apolipoprotein H. (362 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000004933	LOC112137153	ENSOMEP00000004933	ENSOMEP00000007728	Vitellogenin domain-containing protein.	Apolipoprotein H.	0.692
ENSOMEP00000004933	LOC112137180	ENSOMEP00000004933	ENSOMEP00000007769	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.692
ENSOMEP00000004933	LOC112143596	ENSOMEP00000004933	ENSOMEP00000032147	Vitellogenin domain-containing protein.	Apolipoprotein Eb.	0.862
LOC112137153	ENSOMEP00000004933	ENSOMEP00000007728	ENSOMEP00000004933	Apolipoprotein H.	Vitellogenin domain-containing protein.	0.692
LOC112137153	LOC112142808	ENSOMEP00000007728	ENSOMEP00000025846	Apolipoprotein H.	Apolipoprotein Ba.	0.692
LOC112137153	LOC112150654	ENSOMEP00000007728	ENSOMEP00000007979	Apolipoprotein H.	PLAT domain-containing protein.	0.667
LOC112137153	LOC112157799	ENSOMEP00000007728	ENSOMEP00000005033	Apolipoprotein H.	Apolipoprotein Bb, tandem duplicate 2.	0.692
LOC112137153	lpl	ENSOMEP00000007728	ENSOMEP00000007951	Apolipoprotein H.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.667
LOC112137180	ENSOMEP00000004933	ENSOMEP00000007769	ENSOMEP00000004933	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.692
LOC112137180	LOC112142808	ENSOMEP00000007769	ENSOMEP00000025846	Uncharacterized protein.	Apolipoprotein Ba.	0.692
LOC112137180	LOC112150654	ENSOMEP00000007769	ENSOMEP00000007979	Uncharacterized protein.	PLAT domain-containing protein.	0.667
LOC112137180	LOC112157799	ENSOMEP00000007769	ENSOMEP00000005033	Uncharacterized protein.	Apolipoprotein Bb, tandem duplicate 2.	0.692
LOC112137180	lpl	ENSOMEP00000007769	ENSOMEP00000007951	Uncharacterized protein.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.667
LOC112142808	LOC112137153	ENSOMEP00000025846	ENSOMEP00000007728	Apolipoprotein Ba.	Apolipoprotein H.	0.692
LOC112142808	LOC112137180	ENSOMEP00000025846	ENSOMEP00000007769	Apolipoprotein Ba.	Uncharacterized protein.	0.692
LOC112142808	LOC112143596	ENSOMEP00000025846	ENSOMEP00000032147	Apolipoprotein Ba.	Apolipoprotein Eb.	0.862
LOC112143596	ENSOMEP00000004933	ENSOMEP00000032147	ENSOMEP00000004933	Apolipoprotein Eb.	Vitellogenin domain-containing protein.	0.862
LOC112143596	LOC112142808	ENSOMEP00000032147	ENSOMEP00000025846	Apolipoprotein Eb.	Apolipoprotein Ba.	0.862
LOC112143596	LOC112157799	ENSOMEP00000032147	ENSOMEP00000005033	Apolipoprotein Eb.	Apolipoprotein Bb, tandem duplicate 2.	0.862
LOC112150654	LOC112137153	ENSOMEP00000007979	ENSOMEP00000007728	PLAT domain-containing protein.	Apolipoprotein H.	0.667