(15 nodes) Regulation of insulin-like growth factor receptor signaling pathway network (Oryzias melastigma)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSOMEP00000030108	Insulin-like growth factor binding protein 6b. (199 aa)
	LOC112139901	Androgen receptor. (718 aa)
	LOC112148633	NK3 homeobox 1. (185 aa)
	LOC112153467	Uncharacterized protein. (678 aa)
	LOC112156694	Insulin-like growth factor binding protein 5a. (251 aa)
	igfbp2	Insulin-like growth factor binding protein 2a. (287 aa)
	LOC112150930	Insulin-like growth factor binding protein 1a. (262 aa)
	ghsr	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	ENSOMEP00000018886	Insulin-like growth factor binding protein 2b. (248 aa)
	inppl1	Inositol polyphosphate phosphatase-like 1a. (1249 aa)
	LOC112142636	Inositol polyphosphate phosphatase-like 1b. (1221 aa)
	IGFBP4	Insulin like growth factor binding protein 4. (261 aa)
	ENSOMEP00000034181	IGFBP N-terminal domain-containing protein. (151 aa)
	LOC112155410	Insulin-like growth factor binding protein 5a. (266 aa)
	LOC112145457	Uncharacterized protein. (179 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000030108	LOC112150930	ENSOMEP00000030108	ENSOMEP00000013377	Insulin-like growth factor binding protein 6b.	Insulin-like growth factor binding protein 1a.	0.538
LOC112139901	LOC112148633	ENSOMEP00000004685	ENSOMEP00000007563	Androgen receptor.	NK3 homeobox 1.	0.575
LOC112139901	LOC112153467	ENSOMEP00000004685	ENSOMEP00000012388	Androgen receptor.	Uncharacterized protein.	0.897
LOC112142636	inppl1	ENSOMEP00000032145	ENSOMEP00000022976	Inositol polyphosphate phosphatase-like 1b.	Inositol polyphosphate phosphatase-like 1a.	0.896
LOC112145457	LOC112150930	ENSOMEP00000035026	ENSOMEP00000013377	Uncharacterized protein.	Insulin-like growth factor binding protein 1a.	0.511
LOC112148633	LOC112139901	ENSOMEP00000007563	ENSOMEP00000004685	NK3 homeobox 1.	Androgen receptor.	0.575
LOC112148633	LOC112153467	ENSOMEP00000007563	ENSOMEP00000012388	NK3 homeobox 1.	Uncharacterized protein.	0.575
LOC112150930	ENSOMEP00000030108	ENSOMEP00000013377	ENSOMEP00000030108	Insulin-like growth factor binding protein 1a.	Insulin-like growth factor binding protein 6b.	0.538
LOC112150930	LOC112145457	ENSOMEP00000013377	ENSOMEP00000035026	Insulin-like growth factor binding protein 1a.	Uncharacterized protein.	0.511
LOC112153467	LOC112139901	ENSOMEP00000012388	ENSOMEP00000004685	Uncharacterized protein.	Androgen receptor.	0.897
LOC112153467	LOC112148633	ENSOMEP00000012388	ENSOMEP00000007563	Uncharacterized protein.	NK3 homeobox 1.	0.575
inppl1	LOC112142636	ENSOMEP00000022976	ENSOMEP00000032145	Inositol polyphosphate phosphatase-like 1a.	Inositol polyphosphate phosphatase-like 1b.	0.896