(10 nodes) Behavioral response to cocaine network (Oryzias melastigma)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSOMEP00000024352	Protein kinase domain-containing protein. (104 aa)
	ENSOMEP00000020723	Protein phosphatase 1, regulatory (inhibitor) subunit 1B. (134 aa)
	LOC112148105	Homer scaffold protein 1b. (358 aa)
	drd4	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (456 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (178 aa)
	ENSOMEP00000014983	Protein kinase domain-containing protein. (137 aa)
	LOC112157078	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
	ENSOMEP00000029902	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (480 aa)

Your Current Organism:

Oryzias melastigma

NCBI taxonomy Id: 30732
Other names: Aplocheilus melastigmus, Indian medaka, Java medaka, O. melastigma, marine medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOMEP00000014983	ENSOMEP00000020723	ENSOMEP00000014983	ENSOMEP00000020723	Protein kinase domain-containing protein.	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	0.715
ENSOMEP00000014983	PPP1R1B	ENSOMEP00000014983	ENSOMEP00000013428	Protein kinase domain-containing protein.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.715
ENSOMEP00000020723	ENSOMEP00000014983	ENSOMEP00000020723	ENSOMEP00000014983	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	Protein kinase domain-containing protein.	0.715
ENSOMEP00000020723	ENSOMEP00000024352	ENSOMEP00000020723	ENSOMEP00000024352	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	Protein kinase domain-containing protein.	0.715
ENSOMEP00000020723	cdk5	ENSOMEP00000020723	ENSOMEP00000006243	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.715
ENSOMEP00000024352	ENSOMEP00000020723	ENSOMEP00000024352	ENSOMEP00000020723	Protein kinase domain-containing protein.	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	0.715
ENSOMEP00000024352	PPP1R1B	ENSOMEP00000024352	ENSOMEP00000013428	Protein kinase domain-containing protein.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.715
LOC112157078	drd3	ENSOMEP00000019096	ENSOMEP00000005673	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.746
PPP1R1B	ENSOMEP00000014983	ENSOMEP00000013428	ENSOMEP00000014983	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Protein kinase domain-containing protein.	0.715
PPP1R1B	ENSOMEP00000024352	ENSOMEP00000013428	ENSOMEP00000024352	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Protein kinase domain-containing protein.	0.715
PPP1R1B	cdk5	ENSOMEP00000013428	ENSOMEP00000006243	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.715
cdk5	ENSOMEP00000020723	ENSOMEP00000006243	ENSOMEP00000020723	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	0.715
cdk5	PPP1R1B	ENSOMEP00000006243	ENSOMEP00000013428	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.715
drd3	LOC112157078	ENSOMEP00000005673	ENSOMEP00000019096	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.746
drd3	drd4	ENSOMEP00000005673	ENSOMEP00000005478	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	0.746
drd4	drd3	ENSOMEP00000005478	ENSOMEP00000005673	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.746